Protein Information

Cytoscape View


UniProt AC / UniProt ID O14841 / OPLA_HUMAN
Protein Name 5-oxoprolinase
Gene Name Name: OPLAH
Organism Homo sapiens (Human)

PRO ID PR:O14841
DAG View
PRO Name 5-oxoprolinase (human)
Definition A 5-oxoprolinase that is encoded in the genome of human.
Short Label hOPLAH
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species


O14841 (OPLAH) as Substrate



Site PTM Type PTM Enzyme Score Source PMID
T81 Phosphorylation PhosphoSitePlus
T82 Phosphorylation PhosphoSitePlus
T149 Phosphorylation PhosphoSitePlus
T151 Phosphorylation PhosphoSitePlus   UniProt 23186163
K385 Ubiquitination PhosphoSitePlus
S419 Phosphorylation PhosphoSitePlus
T639 Phosphorylation PhosphoSitePlus
S642 Phosphorylation PhosphoSitePlus
T654 Phosphorylation PhosphoSitePlus
T763 Phosphorylation PhosphoSitePlus
K906 Ubiquitination PhosphoSitePlus
S1065 Phosphorylation HPRD 20068231
K1222 Acetylation PhosphoSitePlus
K1232 Acetylation PhosphoSitePlus
S1265 Phosphorylation PhosphoSitePlus


PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
T151 K151 Biomuta DOID:3571 / liver cancer [ icgc ]
S419 F419 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
K906 N906 Biomuta DOID:1324 / lung cancer [ cosmic, tcga ]
S1265 * Biomuta DOID:363 / uterine cancer [ tcga ]