Protein Information

Cytoscape View

UniProt AC / UniProt ID O14613 / BORG1_HUMAN
Protein Name Cdc42 effector protein 2
Gene Name Name: CDC42EP2
Organism Homo sapiens (Human)

PRO ID PR:O14613
DAG View
PRO Name cdc42 effector protein 2 (human)
Definition A cdc42 effector protein 2 that is encoded in the genome of human.
Short Label hCDC42EP2
Category organism-gene

Interactive Sequence View

Select/align proteoforms across species

O14613 (CDC42EP2) as Substrate

Site PTM Type PTM Enzyme Score Source PMID
Phosphorylation PRO
S2 Acetylation UniProt 22814378
S2 Phosphorylation PhosphoSitePlus
Y8 Phosphorylation PhosphoSitePlus
S26 Phosphorylation PhosphoSitePlus
S31 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976
T88 Phosphorylation PhosphoSitePlus
T90 Phosphorylation PhosphoSitePlus
S101 Phosphorylation P28482 (MAPK1) HPRD   neXtProt   PhosphoSitePlus 18691976, 22028470
S109 Phosphorylation PhosphoSitePlus
T137 Phosphorylation PhosphoSitePlus
S141 Phosphorylation HPRD   PhosphoSitePlus   UniProt 18691976, 20068231


PRO ID (Short Label) Sites PTM Enzyme Source PMID
PR:000046662 (hCDC42EP2/PhosRes+) p PRO

PTM sites affected in variants

Site Variant Source PMID Disease [Sample source]
S101 F101 Biomuta DOID:1909 / melanoma [ icgc, tcga ]
S109 F109 Biomuta DOID:1909 / melanoma [ tcga ]
S141 F141 Biomuta DOID:1909 / melanoma [ icgc, tcga ]