TI - Transport and Metabolism . AB - Gene content analyses of M.massiliensis revealed that 432/3697 genes ( 12% ) encode transporters ( Table S2 ) . This transport capacity is much larger than that in any of the 179 bacteria listed in http : [10] , which have an average fraction of transport genes of 5.5% + - 1.7% . The M.massiliensis genome encodes a particularly large number of genes for the transport of ions , amino acids , and sugars . This high transport capacity is in contrast with the constrained metabolism of M.massiliensis , illustrated by the lack of a gene encoding Glk , a glucokinase involved in the metabolism of unPHOSphorylated intracellular glucose ; this enzyme is widespread , as it is present in 200/282 bacteria and 14/19 beta-proteobacteria in the Kegg database [11] . Although pathways for the synthesis of purines , pyrimidines and amino acids are identified in M.massiliensis , the choice of enzymatic route appears to be limited with respect to what is observed in R.solanaceraum , as illustrated by purine metabolism (Figure S1) . In particular , the PHOSphorylation capacities of sugars and nucleotides are strongly reduced .