PR:000000471	smad2 sequence variant L440R (human)	hSMAD2/var:L440R|smad2 sequence variant 2 (human)|UniProtKB:Q15796-1, Leu-440, CHEBI:29952		associated_with_disease_progression	DOID:5672	large intestine cancer			PMID:8752209	EXP	NCBITaxon:9606		UniProtKB_VAR:VAR_011377	20080301	PRO:CNA