PR:000000052	TGF-beta receptor type-2 sequence variant R460C (human)	hTGFBR2/var:R460C|TGF-beta receptor type-2 sequence variant 11 (human)|UniProtKB:P37173-1, Arg-460, CHEBI:29950		associated_with_disease_progression	DOID:0050466	Loeys-Dietz syndrome			PMID:15731757	EXP	NCBITaxon:9606		UniProtKB_VAR:VAR_029760	20080301	PRO:CNA