[Term]
id: PR:P28700-1
name: retinoic acid receptor RXR-alpha isoform 1 (mouse)
def: "A retinoic acid receptor RXR-alpha (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P28700-1." [PMID:1312497, PMID:8954108, PRO:KRC, UniProtKB:P28700]
comment: Category=organism-sequence. Note: PMID:1312497 shows sloning of cDNAs for three RXR genes, alpha, beta, and gamma. PMID:8954108 shows that RNAse protection identified the presence of the full length Rxr-alpha transcript in all tissues assayed, and a smaller transcript present in testis and at a low level in liver. RACE-PCR followed by cloning and sequencing identified the full length cDNA encoding protein isoform 1, and also two shorter cDNAs with differing 5' ends, 1 clone of Rxr-alpha-2 and 15 clones of Rxr-alpha-3. Analysis of the sequence of the alpha-2 and alpha-3 transcripts indicated that they both code for the same protein with an ATG start codon present in the sequence of exon 2.
synonym: "mRXRA/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "RXR-alpha1 (mouse)" EXACT []
xref: UniProtKB:P28700-1
is_a: PR:P28700 ! retinoic acid receptor RXR-alpha (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus