[Term]
id: PR:P00382
name: dihydrofolate reductase type 1 (Escherichia coli)
def: "A protein that is a translation product of any of the plasmid-encoded copies of the dhfrI gene in Escherichia coli." [PRO:DAN, UniProtKB:P00382]
comment: Category=organism-gene. Requested by=PubChem. Note: The plasmid R721 dhfrI, plasmid pAPEC-O2-R folA, and plasmid pECTm80 dhfrA1 genes encode identical proteins.
synonym: "dhfrI" RELATED Gene-based [UniProtKB:P00382]
synonym: "dhfrI (ECOLX)" EXACT PRO-short-label [PRO:DNx]
synonym: "dihydrofolate reductase type I (Escherichia coli)" EXACT [UniProtKB:P00382]
synonym: "trimethoprim resistance protein (Escherichia coli)" EXACT [UniProtKB:P00382]
xref: UniProtKB:P00382
is_a: PR:000000001 ! protein
relationship: has_gene_template NCBIGene:10549022 ! plasmid pECTm80 dhfrA1 (Escherichia coli)
relationship: has_gene_template NCBIGene:1238688 ! plasmid R721 dhfrI (Escherichia coli)
relationship: has_gene_template NCBIGene:3244885 ! plasmid pAPEC-O2-R folA (Escherichia coli)
relationship: only_in_taxon NCBITaxon:562 ! Escherichia coli