[Term]
id: PR:000050026
name: hemoglobin subunit beta
def: "A beta-globin that is a translation product of the human HBB gene or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=gene.
synonym: "HBB" EXACT PRO-short-label [PRO:DNx]
synonym: "hemoglobin beta chain" RELATED []
is_a: PR:000008457 ! beta-globin

[Term]
id: PR:000020114
name: hemoglobin subunit beta, initiator methionine removed form
def: "A hemoglobin subunit beta that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "HBB/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:000050026 ! hemoglobin subunit beta

[Term]
id: PR:000020115
name: hemoglobin subunit beta proteolytic cleavage product
def: "A hemoglobin subunit beta that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "HBB/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000050026 ! hemoglobin subunit beta

[Term]
id: PR:000050468
name: hemoglobin subunit beta N-1-deoxyfructosylated 1
def: "A hemoglobin subunit beta, initiator methionine removed form that has been N-1-deoxyfructosylated at the position equivalent to Val-2 of the sequence represented by UniProtKB:P68871-1 or a 1:1 ortholog thereof." [PRO:DAN]
comment: Category=modification.
synonym: "HBB/InitMet-/dFruc:1" EXACT PRO-short-label [PRO:DAN]
synonym: "beta-N-1-deoxy fructosyl hemoglobin subunit" BROAD [PRO:DAN]
is_a: PR:000020114 ! hemoglobin subunit beta, initiator methionine removed form

[Term]
id: PR:P68871
name: hemoglobin subunit beta (human)
def: "A hemoglobin subunit beta that is encoded in the genome of human." [PRO:DNx, UniProtKB:P68871]
comment: Category=organism-gene.
synonym: "HBB" RELATED Gene-based [UniProtKB:P68871]
synonym: "hHBB" EXACT PRO-short-label [PRO:DNx]
synonym: "beta-globin (human)" EXACT [UniProtKB:P68871]
synonym: "hemoglobin beta chain (human)" EXACT [UniProtKB:P68871]
xref: UniProtKB:P68871
intersection_of: has_gene_template HGNC:4827 ! HBB (human)
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000050026 ! hemoglobin subunit beta

[Term]
id: PR:P02112
name: hemoglobin subunit beta (chicken)
def: "A hemoglobin subunit beta that is a translation product of the HBB gene in chicken." [PRO:DAN, UniProtKB:P02112]
comment: Category=organism-gene.
synonym: "HBB" RELATED Gene-based [UniProtKB:P02112]
synonym: "chick-HBB" EXACT PRO-short-label [PRO:DNx]
synonym: "beta-globin (chicken)" EXACT [UniProtKB:P02112]
synonym: "hemoglobin beta chain (chicken)" EXACT [UniProtKB:P02112]
xref: UniProtKB:P02112
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000050026 ! hemoglobin subunit beta
relationship: has_gene_template NCBIGene:396485 ! HBB (chicken)

[Term]
id: PR:000056675
name: hemoglobin subunit beta O-glycosylated 1 (human)
def: "A hemoglobin subunit beta (human) that has been O-glycosylated at the residue equivalent to Ser-45 of the amino acid sequence represented by UniProtKB:P68871-1, in which the glycan composition is represented by GlyTouCan:G27391WQ. Example: UniProtKB:P68871-1, Ser-45, MOD:00002~GNO:G27391WQ." [GlyGen:P68871-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hHBB/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P68871-1, Ser-45, MOD:00002~GNO:G27391WQ" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P68871 ! hemoglobin subunit beta (human)
relationship: has_part GNO:G27391WQ ! G27391WQ
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000047681
name: hemoglobin subunit beta, initiator methionine removed form (human)
def: "A hemoglobin subunit beta (human) that has had the initiator methionine removed. UniProtKB:P68871, 2-147." [PRO:DNx, Reactome:R-HSA-1008196, Reactome:R-HSA-2168872, Reactome:R-HSA-2230936]
comment: Category=organism-modification.
synonym: "hHBB/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000052976" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P68871, 2-147" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1008196 "PR:000047681 located_in GO:0005829"
xref: Reactome:R-HSA-2168872 "PR:000047681 located_in GO:0005576"
xref: Reactome:R-HSA-2230936 "PR:000047681 located_in GO:0071682"
xref: Reactome:R-HSA-6800191 "PR:000047681 located_in GO:1904724"
xref: Reactome:R-HSA-6801015 "PR:000047681 located_in GO:1904813"
xref: Reactome:R-HSA-9625193 "PR:000047681 located_in GO:0043202"
xref: Reactome:R-HSA-9631108 "PR:000047681 located_in GO:0031906"
xref: TDR:5507
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P68871 ! hemoglobin subunit beta (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens