[Term]
id: PR:000049133
name: ribosomal protein S6 kinase alpha-6 phosphorylated 1 (human)
def: "A ribosomal protein S6 kinase alpha-6 (human) that has been post-translationally modified to include phosphoserine at positions 232, 372 and 389, and phosphothreonine at position 581 of the amino acid sequence represented by UniProtKB:Q9UK32-1. Example: UniProtKB:Q9UK32-1, Ser-232/Ser-372/Ser-389, MOD:00046|Thr-581, MOD:00047." [PMID:15632195, PRO:DNx, PRO:KER, Reactome:R-HSA-444293]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:15632195). Kinase=("RPS6KA6"; PR:Q9UK32-1; Ser-232/Ser-389). Kinase=("MAPK"; PR:000000019; Ser-372/Thr-581).
synonym: "hRPS6KA6/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9UK32-1, Ser-232/Ser-372/Ser-389, MOD:00046|Thr-581, MOD:00047" NARROW PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-444293 "PR:000049133 located_in GO:0005654"
is_a: PR:Q9UK32 ! ribosomal protein S6 kinase alpha-6 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens