[Term]
id: PR:000044818
name: serine/threonine-protein kinase PLK1 phosphorylated 1 (human)
def: "A serine/threonine-protein kinase PLK1 (human) that has been phosphorylated on a Ser residue that is within a 14-3-3 recognition motif, and a Thr residue that is in the activation loop and is an Aurora kinase phosphorylation site. UniProtKB:P53350, Ser-99, MOD:00046|Thr-210, MOD:00047." [PMID:23695676, PRO:CNA]
comment: Category=organism-modification. Evidence=(ECO:0000006, PMID:23695676). Kinase=("AKT"; PR:000029189; Ser-99). Kinase=("AURKA"; PR:O14965; Thr-210). Note: Proteoform created based on papers selected via the eFIP text mining tool.
synonym: "hPLK1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P53350, Ser-99, MOD:00046|Thr-210, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P53350 ! serine/threonine-protein kinase PLK1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens