[Term]
id: PR:000037245
name: chymotrypsin-like elastase family member 2A, mature form (mouse)
def: "A chymotrypsin-like elastase family member 2A, pro-form (mouse) that has had the activation peptide removed by proteolytic cleavage. UniProtKB:P05208, 31-271." [PMID:20179351, PMID:3641189, PRO:KRC]
comment: Category=organism-modification. Note: Figure 3C in PMID:20179351 shows the Western blot analysis of WT and Tg-ELA2 (Tg) epidermal and dermal extracts, using an anti-FLAG antibody, revealing exogenous ELA2flag as pro-forms and active forms in the epidermis of transgenic animals. Figure 1 in PMID:3641189 shows sequence of mRNA corresponding to preproenzyme and presumes start site of active enzyme based on homology with porcine enzyme.
synonym: "Ela2 (mouse)" RELATED []
synonym: "Cela2a (mouse)" RELATED []
synonym: "PRO_0000027688" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "mCELA2A/mature" EXACT PRO-short-label [PRO:DAN]
synonym: "elastase 2 (mouse)" RELATED []
synonym: "UniProtKB:P05208, 31-271" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: PR:000037244 ! chymotrypsin-like elastase family member 2A, pro-form (mouse)
intersection_of: lacks_part SO:0001062 ! propeptide
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus