[Term]
id: PR:P17763
name: genome polyprotein (Dengue virus 1 Nauru/West Pac/1974)
def: "A dengue virus genome polyprotein that is encoded in the genome of Dengue virus 1 Nauru/West Pac/1974." [PRO:ES]
comment: Category=organism-gene.
synonym: "polyprot" RELATED Gene-based [UniProtKB:P17763]
synonym: "polyprot (DEN1W)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P17763
intersection_of: only_in_taxon NCBITaxon:11059 ! Dengue virus 1 Nauru/West Pac/1974
intersection_of: PR:000036816 ! dengue virus genome polyprotein
relationship: has_gene_template NCBIGene:5075725 ! polyprot (Dengue virus 1 Nauru/West Pac/1974)

[Term]
id: PR:000036816
name: dengue virus genome polyprotein
def: "A protein that is a translation product of the dengue virus serotype 2 genomic RNA or a 1:1 ortholog thereof." [PRO:ES]
comment: Category=gene. Requested by=IDODEN. The dengue virus contains a 10.7 kb single-stranded RNA genome of positive strand polarity with a type I cap at the 5' terminus. The RNA genome is translated into a large glycosylated polyprotein precursor with proteins that are arranged in the order NH2-C-prM-E-NS1-NS2A-NS2B-NS3-NS4A-NS4B-NS5-COOH. Proteolytic processing in the region of the structural proteins is mediated by a host cell signal peptidase that is located within the endoplasmic reticulum. [PMID:12297031, PRO:ES]
synonym: "DenV-polyprot" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000000001 ! protein