[Term] id: PR:000035849 name: histone-lysine N-methyltransferase MECOM def: "A protein that is a translation product of the human MECOM gene or a 1:1 ortholog thereof." [PRO:DAN] comment: Category=gene. synonym: "EVI1" RELATED Gene-based [] synonym: "MDS1" RELATED Gene-based [] synonym: "EVI-1" EXACT [] synonym: "MECOM" EXACT PRO-short-label [PRO:DNx] synonym: "PRDM3" RELATED Gene-based [] synonym: "MDS1 and EVI1 complex locus protein" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:Q03112-8 name: histone-lysine N-methyltransferase MECOM isoform h8 (human) def: "A histone-lysine N-methyltransferase MECOM (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q03112-8." [PRO:DNx, UniProtKB:Q03112] comment: Category=organism-sequence. synonym: "hMECOM/iso:h8" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q03112-8 is_a: PR:Q03112 ! histone-lysine N-methyltransferase MECOM (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q03112-9 name: histone-lysine N-methyltransferase MECOM isoform MDS1 (human) def: "A histone-lysine N-methyltransferase MECOM isoform MDS1 that is encoded in the genome of human." [PRO:DAN] comment: Category=organism-sequence. synonym: "hMECOM/iso:MDS1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q03112-9 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000010271 ! histone-lysine N-methyltransferase MECOM isoform MDS1 [Term] id: PR:Q03112-3 name: histone-lysine N-methyltransferase MECOM isoform Evi-1c (human) def: "A histone-lysine N-methyltransferase MECOM isoform Evi-1c that is encoded in the genome of human." [PRO:DAN] comment: Category=organism-sequence. synonym: "hMECOM/iso:Evi-1c" EXACT PRO-short-label [PRO:DNx] synonym: "MDS1 and EVI1 complex locus protein EVI1 isoform 2 (human)" EXACT [UniProtKB:Q03112] synonym: "MDS1 and EVI1 complex locus protein EVI1 isoform Mds1/Evi1 (human)" EXACT [UniProtKB:Q03112] xref: UniProtKB:Q03112-3 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035851 ! histone-lysine N-methyltransferase MECOM isoform Evi-1c [Term] id: PR:Q03112-1 name: histone-lysine N-methyltransferase MECOM isoform Evi-1a (human) def: "A histone-lysine N-methyltransferase MECOM isoform Evi-1a that is encoded in the genome of human." [PRO:DAN] comment: Category=organism-sequence. synonym: "hMECOM/iso:Evi-1a" EXACT PRO-short-label [PRO:DNx] synonym: "MDS1 and EVI1 complex locus protein EVI1 isoform 1 (human)" EXACT [UniProtKB:Q03112] synonym: "MDS1 and EVI1 complex locus protein EVI1 isoform Long (human)" EXACT [UniProtKB:Q03112] xref: UniProtKB:Q03112-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000007234 ! histone-lysine N-methyltransferase MECOM isoform Evi-1a [Term] id: PR:Q03112-6 name: histone-lysine N-methyltransferase MECOM isoform 6 (human) def: "A histone-lysine N-methyltransferase MECOM isoform 6 that is encoded in the genome of human." [PRO:DAN] comment: Category=organism-sequence. synonym: "hMECOM/iso:6" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q03112-6 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035854 ! histone-lysine N-methyltransferase MECOM isoform 6 [Term] id: PR:Q03112-7 name: histone-lysine N-methyltransferase MECOM isoform 7 (human) def: "A histone-lysine N-methyltransferase MECOM isoform 7 that is encoded in the genome of human." [PRO:DAN] comment: Category=organism-sequence. synonym: "hMECOM/iso:7" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q03112-7 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000044536 ! histone-lysine N-methyltransferase MECOM isoform 7 [Term] id: PR:Q03112-4 name: histone-lysine N-methyltransferase MECOM isoform 4 (human) def: "A histone-lysine N-methyltransferase MECOM isoform 4 that is encoded in the genome of human." [PRO:DAN] comment: Category=organism-sequence. synonym: "hMECOM/iso:4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q03112-4 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035852 ! histone-lysine N-methyltransferase MECOM isoform 4 [Term] id: PR:Q03112-5 name: histone-lysine N-methyltransferase MECOM isoform 5 (human) def: "A histone-lysine N-methyltransferase MECOM isoform 5 that is encoded in the genome of human." [PRO:DAN] comment: Category=organism-sequence. synonym: "hMECOM/iso:5" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q03112-5 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035853 ! histone-lysine N-methyltransferase MECOM isoform 5 [Term] id: PR:Q03112 name: histone-lysine N-methyltransferase MECOM (human) def: "A histone-lysine N-methyltransferase MECOM that is encoded in the genome of human." [PRO:DAN] comment: Category=organism-gene. synonym: "EVI1" RELATED Gene-based [UniProtKB:Q03112] synonym: "MDS1" RELATED Gene-based [UniProtKB:Q03112] synonym: "MECOM" RELATED Gene-based [UniProtKB:Q03112] synonym: "PRDM3" RELATED Gene-based [UniProtKB:Q03112] synonym: "hMECOM" EXACT PRO-short-label [PRO:DNx] synonym: "EVI-1 (human)" EXACT [UniProtKB:Q03112] synonym: "myelodysplasia syndrome 1 protein (human)" EXACT [UniProtKB:Q03112] synonym: "MDS1 and EVI1 complex locus protein (human)" EXACT [UniProtKB:Q03112] synonym: "myelodysplasia syndrome-associated protein 1 (human)" EXACT [UniProtKB:Q03112] synonym: "ecotropic virus integration site 1 protein homolog (human)" EXACT [UniProtKB:Q03112] xref: Reactome:R-HSA-5634790 "PR:Q03112 located_in GO:0005829" xref: UniProtKB:Q03112 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000035849 ! histone-lysine N-methyltransferase MECOM relationship: has_gene_template HGNC:3498 ! MECOM (human)