[Term]
id: PR:000035501
name: spindle assembly checkpoint component MAD3 phosphorylated 1 (yeast)
def: "A spindle assembly checkpoint component MAD3 phosphorylated 1 in yeast. UniProtKB:P47074, Ser-268 and (Ser-466 and/or Ser-504), MOD:00046." [PMID:15970700, PRO:DAN, PRO:KER]
comment: Category=organism-modification. Note: Ser-268 is the major site phosphorylated by CDC5; Sites phosphorylated by IPL1 are unknown. Kinase=("CDC5"; PR:000029227). Kinase=("IPL1"; PR:000029237).
synonym: "yMAD3/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P47074, Ser-268 and (Ser-466 and/or Ser-504), MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000035500 ! spindle assembly checkpoint component MAD3 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:P47074
name: spindle assembly checkpoint component MAD3 (yeast)
def: "A spindle assembly checkpoint component MAD3 that is encoded in the genome of yeast." [PMID:15970700, PRO:KER]
comment: Category=organism-gene.
synonym: "MAD3" RELATED Gene-based [UniProtKB:P47074]
synonym: "J1341" RELATED Gene-based [UniProtKB:P47074]
synonym: "yMAD3" EXACT PRO-short-label [PRO:DNx]
synonym: "YJL013C" RELATED Gene-based [UniProtKB:P47074]
synonym: "Mitotic MAD3 protein" BROAD [PRO:DNx]
synonym: "mitotic MAD3 protein (yeast)" EXACT [UniProtKB:P47074]
xref: UniProtKB:P47074
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000035499 ! spindle assembly checkpoint component MAD3
relationship: has_gene_template SGD:S000003550 ! MAD3 (yeast)

[Term]
id: PR:000035499
name: spindle assembly checkpoint component MAD3
def: "A protein that is a translation product of the yeast MAD3 gene or a 1:1 ortholog thereof. MAD3 is related to BUB1 and BUB1B, all of which contain the Mad3/BUB1 homology region 1 (Pfam:PF00831), but MAD3 lacks the C-terminal Protein kinase domain (Pfam:PF00069)." [PMID:15970700, PMID:22698286, PRO:KER]
comment: Category=gene.
synonym: "MAD3" EXACT PRO-short-label [PRO:DNx]
synonym: "Mitotic MAD3 protein" BROAD [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000035503
name: spindle assembly checkpoint component MAD3 phosphorylated 2 (yeast)
def: "A spindle assembly checkpoint component MAD3 phosphorylated 2 in yeast. Phosphorylation is necessary for normal response to a lack of kinetochore tension but not for response to lack of microtubule binding to kinetochores. In addition to the phosphorylation annotated, this form might also be phosphorylated on Ser-10 and Ser-486. UniProtKB:P47074, Ser-303/Ser-337, MOD:00046." [PMID:17504936, PRO:KER]
comment: Category=organism-modification. Kinase=("Ipl1"; PR:000029237).
synonym: "yMAD3/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P47074, Ser-303/Ser-337, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000035502 ! spindle assembly checkpoint component MAD3 phosphorylated 2
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000035506
name: spindle assembly checkpoint component MAD3 unphosphorylated form (yeast)
def: "A spindle assembly checkpoint component MAD3 unphosphorylated form in yeast." [PRO:KER]
comment: Category=organism-modification.
synonym: "yMAD3/PhosRes-" EXACT PRO-short-label [PRO:DNx]
synonym: "yMAD3 unphosphorylated" RELATED []
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000035505 ! spindle assembly checkpoint component MAD3 unphosphorylated form