[Term]
id: PR:P06612
name: DNA topoisomerase 1 (Escherichia coli K-12)
def: "A type 1A DNA topoisomerase 1 that is encoded in the genome of Escherichia coli K-12." [PRO:DNx, UniProtKB:P06612]
comment: Category=organism-gene.
synonym: "supX" RELATED Gene-based [UniProtKB:P06612]
synonym: "topA" RELATED Gene-based [UniProtKB:P06612]
synonym: "b1274" RELATED Gene-based [UniProtKB:P06612]
synonym: "JW1266" RELATED Gene-based [UniProtKB:P06612]
synonym: "Ec-topA" EXACT PRO-short-label [PRO:DNx]
synonym: "omega protein" EXACT [PRO:DAN]
synonym: "swivelase (Escherichia coli K-12)" EXACT [UniProtKB:P06612]
synonym: "omega-protein (Escherichia coli K-12)" EXACT [UniProtKB:P06612]
synonym: "relaxing enzyme (Escherichia coli K-12)" EXACT [UniProtKB:P06612]
synonym: "untwisting enzyme (Escherichia coli K-12)" EXACT [UniProtKB:P06612]
synonym: "DNA topoisomerase I (Escherichia coli K-12)" EXACT [UniProtKB:P06612]
xref: EcoCyc:EG11013-MONOMER
xref: UniProtKB:P06612
intersection_of: only_in_taxon NCBITaxon:83333 ! Escherichia coli K-12
intersection_of: PR:000033803 ! type 1A DNA topoisomerase 1
relationship: has_gene_template EcoGene:EG11013 ! topA (Escherichia coli K-12)

[Term]
id: PR:000033803
name: type 1A DNA topoisomerase 1
def: "A protein that is a translation product of the Escherichia coli K-12 topA gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "supX" RELATED []
synonym: "topA" EXACT PRO-short-label [PRO:DNx]
synonym: "swivelase" EXACT []
synonym: "omega-protein" EXACT []
synonym: "relaxing enzyme" EXACT []
synonym: "untwisting enzyme" EXACT []
synonym: "DNA topoisomerase I" BROAD [PRO:DNx]
is_a: PR:000000001 ! protein