[Term]
id: PR:000032212
name: immunoglobulin superfamily containing leucine-rich repeat protein
def: "A protein that is a translation product of the human ISLR gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ISLR" EXACT PRO-short-label [PRO:DNx]
synonym: "UNQ189/PRO215" RELATED Gene-based []
is_a: PR:000000001 ! protein

[Term]
id: PR:O14498
name: immunoglobulin superfamily containing leucine-rich repeat protein (human)
def: "An immunoglobulin superfamily containing leucine-rich repeat protein that is encoded in the genome of human." [PRO:DNx, UniProtKB:O14498]
comment: Category=organism-gene.
synonym: "ISLR" RELATED Gene-based [UniProtKB:O14498]
synonym: "hISLR" EXACT PRO-short-label [PRO:DNx]
synonym: "UNQ189/PRO215" RELATED Gene-based [UniProtKB:O14498]
xref: UniProtKB:O14498
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000032212 ! immunoglobulin superfamily containing leucine-rich repeat protein
relationship: has_gene_template HGNC:6133 ! ISLR (human)

[Term]
id: PR:000050694
name: immunoglobulin superfamily containing leucine-rich repeat protein O-glycosylated 1 (human)
def: "An immunoglobulin superfamily containing leucine-rich repeat protein (human) that has been O-glycosylated at the residue equivalent to Ser-379 of the amino acid sequence represented by UniProtKB:O14498-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O14498-1, Ser-379, MOD:00002~GNO:G43417UB." [GlyGen:O14498-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hISLR/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O14498-1, Ser-379, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O14498 ! immunoglobulin superfamily containing leucine-rich repeat protein (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00002 ! O-glycosyl-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000050695
name: immunoglobulin superfamily containing leucine-rich repeat protein O-glycosylated 2 (human)
def: "An immunoglobulin superfamily containing leucine-rich repeat protein (human) that has been O-glycosylated at the residue equivalent to Thr-371 of the amino acid sequence represented by UniProtKB:O14498-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O14498-1, Thr-371, MOD:00005~GNO:G43417UB." [GlyGen:O14498-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hISLR/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O14498-1, Thr-371, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O14498 ! immunoglobulin superfamily containing leucine-rich repeat protein (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000048055
name: immunoglobulin superfamily containing leucine-rich repeat protein, signal peptide removed form (human)
def: "An immunoglobulin superfamily containing leucine-rich repeat protein (human) that has had the signal peptide removed. UniProtKB:O14498, 19-428." [PRO:DNx, Reactome:R-HSA-8848912, Reactome:R-HSA-8848919]
comment: Category=organism-modification.
synonym: "hISLR/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000312208" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:O14498, 19-428" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-8848912 "PR:000048055 located_in GO:0031093"
xref: Reactome:R-HSA-8848919 "PR:000048055 located_in GO:0005576"
intersection_of: PR:O14498 ! immunoglobulin superfamily containing leucine-rich repeat protein (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens