[Term]
id: PR:000047174
name: probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial, lipoylated 1 (human)
def: "A probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (human) that has been post-translationally modified to include lipoylated lysine at positions 183, 188, 800 and 818 of the amino acid sequence represented by UniProtKB:Q96HY7. UniProtKB:Q96HY7, Lys-183/Lys-188/Lys-800/Lys-818, MOD:00127." [PRO:DNx, Reactome:R-HSA-6792672]
comment: Category=organism-modification.
synonym: "hDHTKD1/Lipo:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q96HY7, Lys-183/Lys-188/Lys-800/Lys-818, MOD:00127" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-6792672 "PR:000047174 located_in GO:0005759"
is_a: PR:Q96HY7 ! probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (human)
relationship: has_part MOD:00127 ! N6-lipoyl-L-lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q96HY7
name: probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial (human)
def: "A probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q96HY7]
comment: Category=organism-gene.
synonym: "DHTKD1" RELATED Gene-based [UniProtKB:Q96HY7]
synonym: "hDHTKD1" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1630" RELATED Gene-based [UniProtKB:Q96HY7]
synonym: "dehydrogenase E1 and transketolase domain-containing protein 1 (human)" EXACT [UniProtKB:Q96HY7]
xref: UniProtKB:Q96HY7
xref: Reactome:R-HSA-6792669 "PR:Q96HY7 located_in GO:0005759"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000031142 ! probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial
relationship: has_gene_template HGNC:23537 ! DHTKD1 (human)

[Term]
id: PR:000031142
name: probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial
def: "A protein that is a translation product of the human DHTKD1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "DHTKD1" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA1630" RELATED Gene-based []
synonym: "dehydrogenase E1 and transketolase domain-containing protein 1" EXACT []
is_a: PR:000000001 ! protein