[Term] id: PR:000024866 name: osteocalcin pre-pro-protein def: "An osteocalcin that has not been proteolytically processed." [PRO:DAN] comment: Category=modification. synonym: "OC-prepro" EXACT PRO-short-label [PRO:DAN] intersection_of: PR:000030444 ! osteocalcin intersection_of: has_part SO:0000418 ! signal_peptide intersection_of: has_part SO:0001062 ! propeptide [Term] id: PR:000024926 name: osteocalcin peptide, undercarboyxylated form def: "An osteocalcin peptide that has been carboxylated on 1-2 of the three eligible residues, corresponding to Glu-17, Glu-21, and Glu-24 of the human mature peptide UniProtKB:P02818." [PRO:DAN] comment: Category=modification. synonym: "ucOC" EXACT PRO-short-label [PRO:DAN] intersection_of: has_component MOD:00041 ! L-gamma-carboxyglutamic acid intersection_of: has_component MOD:00041 ! L-gamma-carboxyglutamic acid intersection_of: PR:000024920 ! osteocalcin peptide [Term] id: PR:000024920 name: osteocalcin peptide def: "An osteocalcin that has had both the signal peptide and the propeptide removed." [PRO:DAN] comment: Category=modification. synonym: "OC" EXACT PRO-short-label [PRO:DAN] intersection_of: PR:000030444 ! osteocalcin intersection_of: lacks_part SO:0000418 ! signal_peptide intersection_of: lacks_part SO:0001062 ! propeptide [Term] id: PR:000024871 name: osteocalcin pro-protein def: "An osteocalcin that has had the signal peptide removed but retains the propeptide." [PRO:DAN] comment: Category=modification. synonym: "OCpro" EXACT PRO-short-label [PRO:DAN] intersection_of: PR:000030444 ! osteocalcin intersection_of: lacks_part SO:0000418 ! signal_peptide intersection_of: has_part SO:0001062 ! propeptide [Term] id: PR:000024914 name: osteocalcin pro-protein, uncarboyxylated form def: "An osteocalcin pro-protein that has not been carboxylated on any of the three eligible residues, corresponding to Glu-17, Glu-21, and Glu-24 of the human mature peptide UniProtKB:P02818. Example: UniProtKB:P02818, 24-100, Glu-68/Glu-72/Glu-75, PR:000026291." [PRO:DAN] comment: Category=modification. synonym: "OCuc-pro" EXACT PRO-short-label [PRO:DAN] intersection_of: lacks_part MOD:00041 ! L-gamma-carboxyglutamic acid intersection_of: PR:000024871 ! osteocalcin pro-protein [Term] id: PR:000024883 name: osteocalcin pro-protein, fully carboyxylated form def: "An osteocalcin pro-protein that has been carboxylated on all three eligible residues, corresponding to Glu-17, Glu-21, and Glu-24 of the human mature peptide UniProtKB:P02818. Example: UniProtKB:P02818, 24-100, Glu-68/Glu-72/Glu-75, MOD:00041." [PRO:DAN] comment: Category=modification. synonym: "cOC-pro" EXACT PRO-short-label [PRO:DAN] intersection_of: has_component MOD:00041 ! L-gamma-carboxyglutamic acid intersection_of: PR:000024871 ! osteocalcin pro-protein [Term] id: PR:000024901 name: osteocalcin pro-protein, undercarboyxylated form def: "An osteocalcin pro-protein that has been carboxylated on 1-2 of the three eligible residues, corresponding to Glu-17, Glu-21, and Glu-24 of the human mature peptide UniProtKB:P02818." [PRO:DAN] comment: Category=modification. synonym: "ucOC-pro" EXACT PRO-short-label [PRO:DAN] intersection_of: has_component MOD:00041 ! L-gamma-carboxyglutamic acid intersection_of: has_component MOD:00041 ! L-gamma-carboxyglutamic acid intersection_of: PR:000024871 ! osteocalcin pro-protein [Term] id: PR:000024932 name: osteocalcin peptide, uncarboyxylated form def: "An osteocalcin peptide that has not been carboxylated on any of the three eligible residues, corresponding to Glu-17, Glu-21, and Glu-24 of the human mature peptide UniProtKB:P02818. Example: UniProtKB:P02818, 52-100, Glu-68/Glu-72/Glu-75, PR:000026291." [PRO:DAN] comment: Category=modification. synonym: "OCuc" EXACT PRO-short-label [PRO:DAN] intersection_of: lacks_part MOD:00041 ! L-gamma-carboxyglutamic acid intersection_of: PR:000024920 ! osteocalcin peptide [Term] id: PR:000046480 name: osteocalcin, signal peptide removed form (human) def: "An osteocalcin (human) that has had the signal peptide removed. UniProtKB:P02818, 24-100." [PRO:DNx, Reactome:R-HSA-6807212] comment: Category=organism-modification. synonym: "hBGLAP/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P02818, 24-100" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-6807212 "PR:000046480 located_in GO:0005788" intersection_of: PR:P02818 ! osteocalcin (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000030444 name: osteocalcin def: "A protein that is a translation product of the human BGLAP gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "BGP" EXACT [] synonym: "BGLAP" EXACT PRO-short-label [PRO:DNx] synonym: "bone Gla protein" EXACT [] synonym: "gamma-carboxyglutamic acid-containing protein" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000024923 name: osteocalcin peptide, fully carboyxylated form def: "An osteocalcin peptide that has been carboxylated on all three eligible residues, corresponding to Glu-17, Glu-21, and Glu-24 of the human mature peptide UniProtKB:P02818. Example: UniProtKB:P02818, 52-100, Glu-68/Glu-72/Glu-75, MOD:00041." [PRO:DAN] comment: Category=modification. synonym: "cOC" EXACT PRO-short-label [PRO:DAN] intersection_of: has_component MOD:00041 ! L-gamma-carboxyglutamic acid intersection_of: PR:000024920 ! osteocalcin peptide [Term] id: PR:P04640 name: osteocalcin (rat) def: "An osteocalcin that is encoded in the genome of rat." [OMA:P04640, PRO:DNx] comment: Category=organism-gene. synonym: "Bglap" RELATED Gene-based [UniProtKB:P04640] synonym: "Bglap2" RELATED Gene-based [UniProtKB:P04640] synonym: "rBGLAP" EXACT PRO-short-label [PRO:DNx] synonym: "BGP (rat)" EXACT [UniProtKB:P04640] synonym: "bone Gla protein (rat)" EXACT [UniProtKB:P04640] synonym: "gamma-carboxyglutamic acid-containing protein (rat)" EXACT [UniProtKB:P04640] xref: UniProtKB:P04640 intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus intersection_of: PR:000030444 ! osteocalcin relationship: has_gene_template RGD:2206 ! Bglap (rat) [Term] id: PR:P02818 name: osteocalcin (human) def: "An osteocalcin that is encoded in the genome of human." [PRO:DNx, UniProtKB:P02818] comment: Category=organism-gene. synonym: "BGLAP" RELATED Gene-based [UniProtKB:P02818] synonym: "hBGLAP" EXACT PRO-short-label [PRO:DNx] synonym: "BGP (human)" EXACT [UniProtKB:P02818] synonym: "bone Gla protein (human)" EXACT [UniProtKB:P02818] synonym: "gamma-carboxyglutamic acid-containing protein (human)" EXACT [UniProtKB:P02818] xref: UniProtKB:P02818 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000030444 ! osteocalcin relationship: has_gene_template HGNC:1043 ! BGLAP (human)