[Term]
id: PR:000044837
name: neuregulin-1 type I-beta4a (mouse)
def: "A neuregulin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein described as NRG type I-beta4 in PMID:11116142." [PMID:11116142, PRO:KRC]
comment: Category=organism-sequence.
synonym: "NRG-beta4 (mouse)" RELATED [PMID:11116142]
synonym: "mNRG1/iso:Ibeta4a" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG type I-beta4a (mouse)" RELATED []
is_a: PR:Q6DR99 ! neuregulin-1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P43322
name: pro-neuregulin-1, membrane-bound isoform (rat)
def: "A pro-neuregulin-1, membrane-bound isoform that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-gene.
synonym: "Ndf" RELATED Gene-based [UniProtKB:P43322]
synonym: "Nrg1" RELATED Gene-based [UniProtKB:P43322]
synonym: "rNRG1" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-NRG1 (rat)" EXACT [UniProtKB:P43322]
xref: UniProtKB:P43322
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000029649 ! pro-neuregulin-1, membrane-bound isoform
relationship: has_gene_template RGD:621341 ! Nrg1 (rat)

[Term]
id: PR:000044839
name: neuregulin-1 type I-beta4a mature form (mouse)
def: "A neuregulin-1 type I-beta4a (mouse) that has been proteolytically processed by the Meltrin beta/ADAM19 metalloprotease to produced a soluble form consisting of the ectodomain." [PMID:11116142, PRO:KRC]
comment: Category=organism-modification.
synonym: "mNRG1/iso:Ibeta4a/mature" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG beta4a mature form (mouse)" RELATED []
synonym: "neuregulin beta4a mature form (mouse)" RELATED []
is_a: PR:000044837 ! neuregulin-1 type I-beta4a (mouse)
relationship: output_of GO:0016485 ! protein processing
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044838
name: neuregulin-1 type I-beta4a precursor (mouse)
def: "A neuregulin-1 type I-beta4a (mouse) that is a transmembrane protein which has not been proteolytically processed." [PMID:11116142, PRO:KRC]
comment: Category=organism-modification.
synonym: "mNRG1/iso:Ibeta4a/precursor" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG type I-beta4a precursor (mouse)" RELATED []
is_a: PR:000044837 ! neuregulin-1 type I-beta4a (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q05199-1
name: pro-neuregulin-1, membrane-bound isoform isoform 1 (chicken)
def: "A pro-neuregulin-1, membrane-bound isoform (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05199-1." [PRO:DNx, UniProtKB:Q05199]
comment: Category=organism-sequence.
synonym: "chick-NRG1/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform ARIA (chicken)" EXACT [UniProtKB:Q05199]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform Ig-NRG (chicken)" EXACT [UniProtKB:Q05199]
xref: UniProtKB:Q05199-1
is_a: PR:Q05199 ! pro-neuregulin-1, membrane-bound isoform (chicken)
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus

[Term]
id: PR:Q6DR99-1
name: neuregulin-1 type III-beta1a (mouse)
def: "A neuregulin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6DR99-1." [PMID:12648463, PMID:24083437, PRO:KRC, UniProtKB:Q6DR99]
comment: Category=organism-sequence.
synonym: "mNRG1/iso:IIIbeta1a" EXACT PRO-short-label [PRO:DAN]
synonym: "neuregulin-1 type III beta1-a (mouse)" EXACT [PRO:DAN, UniProtKB:Q6DR99]
xref: UniProtKB:Q6DR99-1
is_a: PR:Q6DR99 ! neuregulin-1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q05199-4
name: pro-neuregulin-1, membrane-bound isoform isoform 4 (chicken)
def: "A pro-neuregulin-1, membrane-bound isoform (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05199-4." [PRO:DNx, UniProtKB:Q05199]
comment: Category=organism-sequence.
synonym: "chick-NRG1/iso:4" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform CRD-NRG-BETA2B (chicken)" EXACT [UniProtKB:Q05199]
xref: UniProtKB:Q05199-4
is_a: PR:Q05199 ! pro-neuregulin-1, membrane-bound isoform (chicken)
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus

[Term]
id: PR:Q3URY7
name: neuregulin-1 type III-beta1c (mouse)
def: "A neuregulin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3URY7." [PMID:12648463, PMID:24083437, PRO:KRC, UniProtKB:Q3URY7]
comment: Category=organism-sequence.
synonym: "mNRG1/iso:IIIbeta1c" EXACT PRO-short-label [PRO:DAN]
xref: UniProtKB:Q3URY7
is_a: PR:Q6DR99 ! neuregulin-1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q02297-9
name: pro-neuregulin-1, membrane-bound isoform isoform h9 (human)
def: "A pro-neuregulin-1, membrane-bound isoform (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02297-9." [PRO:DNx, UniProtKB:Q02297]
comment: Category=organism-sequence.
synonym: "hNRG1/iso:h9" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform GGF2 (human)" EXACT [UniProtKB:Q02297]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform GGFHPP2 (human)" EXACT [UniProtKB:Q02297]
xref: UniProtKB:Q02297-9
is_a: PR:Q02297 ! pro-neuregulin-1, membrane-bound isoform (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q02297-8
name: pro-neuregulin-1, membrane-bound isoform isoform h8 (human)
def: "A pro-neuregulin-1, membrane-bound isoform (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02297-8." [PRO:DNx, UniProtKB:Q02297]
comment: Category=organism-sequence.
synonym: "hNRG1/iso:h8" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform Beta3 (human)" EXACT [UniProtKB:Q02297]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform GGFHFB1 (human)" EXACT [UniProtKB:Q02297]
xref: UniProtKB:Q02297-8
is_a: PR:Q02297 ! pro-neuregulin-1, membrane-bound isoform (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000029650
name: pro-neuregulin-1, membrane-bound isoform, initiator methionine removed form
def: "A pro-neuregulin-1, membrane-bound isoform that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "NRG1/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:000029649 ! pro-neuregulin-1, membrane-bound isoform

[Term]
id: PR:000029651
name: pro-neuregulin-1, membrane-bound isoform proteolytic cleavage product
def: "A pro-neuregulin-1, membrane-bound isoform that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "NRG1/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000029649 ! pro-neuregulin-1, membrane-bound isoform

[Term]
id: PR:Q8BX76
name: neuregulin-1 type III-beta3 (mouse)
def: "A neuregulin-1 type III-beta3 that is encoded in the genome of mouse." [PMID:12648463, PMID:24083437, PRO:KRC, UniProtKB:Q8BX76]
comment: Category=organism-sequence.
synonym: "mNRG1/iso:IIIbeta3" EXACT PRO-short-label [PRO:DAN]
xref: UniProtKB:Q8BX76
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000044822 ! neuregulin-1 type III-beta3

[Term]
id: PR:Q02297-12
name: pro-neuregulin-1, membrane-bound isoform isoform h12 (human)
def: "A pro-neuregulin-1, membrane-bound isoform (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02297-12." [PRO:DNx, UniProtKB:Q02297]
comment: Category=organism-sequence.
synonym: "hNRG1/iso:h12" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q02297-12
is_a: PR:Q02297 ! pro-neuregulin-1, membrane-bound isoform (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q02297-11
name: pro-neuregulin-1, membrane-bound isoform isoform h11 (human)
def: "A pro-neuregulin-1, membrane-bound isoform (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02297-11." [PRO:DNx, UniProtKB:Q02297]
comment: Category=organism-sequence.
synonym: "hNRG1/iso:h11" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform Type IV-beta1a (human)" EXACT [UniProtKB:Q02297]
xref: UniProtKB:Q02297-11
is_a: PR:Q02297 ! pro-neuregulin-1, membrane-bound isoform (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q02297-10
name: pro-neuregulin-1, membrane-bound isoform isoform 10 (human)
def: "A neuregulin-1 type III-beta3 that is encoded in the genome of human." [PMID:7782315, PRO:DNx, UniProtKB:Q02297]
comment: Category=organism-sequence.
synonym: "hNRG1/iso:10" EXACT PRO-short-label [PRO:DNx]
synonym: "neuregulin-1 type III-beta3 (human)" EXACT [PRO:KRC]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform SMDF (human)" EXACT [UniProtKB:Q02297]
xref: UniProtKB:Q02297-10
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000044822 ! neuregulin-1 type III-beta3

[Term]
id: PR:Q05199-2
name: pro-neuregulin-1, membrane-bound isoform isoform 2 (chicken)
def: "A pro-neuregulin-1, membrane-bound isoform (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05199-2." [PRO:DNx, UniProtKB:Q05199]
comment: Category=organism-sequence.
synonym: "chick-NRG1/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform CRD-NRG-BETA1A (chicken)" EXACT [UniProtKB:Q05199]
xref: UniProtKB:Q05199-2
is_a: PR:Q05199 ! pro-neuregulin-1, membrane-bound isoform (chicken)
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus

[Term]
id: PR:Q3S2T6
name: neuregulin-1 type III-beta3 (rat)
def: "A neuregulin-1 type III-beta3 that is encoded in the genome of rat." [PRO:CNA, UniProtKB:P43322]
comment: Category=organism-sequence.
synonym: "rNRG1/iso:IIIbeta3" EXACT PRO-short-label [PRO:DAN]
xref: UniProtKB:Q3S2T6
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000044822 ! neuregulin-1 type III-beta3

[Term]
id: PR:000044824
name: neuregulin-1 type III-beta1a precursor (mouse)
def: "A neuregulin-1 type III-beta1a (mouse) that has not been proteolytically processed." [PMID:12648463, PMID:24083437, PRO:KRC, UniProtKB:Q6DR99]
comment: Category=organism-modification.
synonym: "mNRG1/iso:IIIbeta1a/precursor" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG type III-beta1a precursor (mouse)" RELATED []
synonym: "neuregulin type III-beta1a precursor (mouse)" RELATED []
is_a: PR:Q6DR99-1 ! neuregulin-1 type III-beta1a (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044825
name: neuregulin-1 type III-beta1c precursor (mouse)
def: "A neuregulin-1 type III-beta1c (mouse) that has not been proteolytically processed." [PMID:12648463, PMID:24083437, PRO:KRC, UniProtKB:Q3URY7]
comment: Category=organism-modification.
synonym: "mNRG1/iso:IIIbeta1c/precursor" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG type III-beta1a precursor (mouse)" RELATED []
synonym: "neuregulin type III-beta1c precursor (mouse)" RELATED []
is_a: PR:Q3URY7 ! neuregulin-1 type III-beta1c (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044822
name: neuregulin-1 type III-beta3
def: "A pro-neuregulin-1, membrane-bound isoform that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02297-10 or a 1:1 ortholog thereof." [PMID:12648463, PMID:7782315, PRO:KRC]
comment: Category=sequence.
synonym: "NRG beta3" RELATED []
synonym: "NRG1/iso:IIIbeta3" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000029649 ! pro-neuregulin-1, membrane-bound isoform

[Term]
id: PR:000044823
name: neuregulin-1 type I-beta1a transmembrane precursor (mouse)
def: "A neuregulin-1 type I-beta1a (mouse) that has not been proteolytically processed." [PMID:11116142, PRO:KRC]
comment: Category=organism-modification.
synonym: "mNRG1/iso:Ibeta1a/precursor" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG beta1a precursor (mouse)" RELATED []
synonym: "neuregulin beta1a precursor (mouse)" RELATED []
is_a: PR:Q6DR98 ! neuregulin-1 type I-beta1a (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044820
name: neuregulin-1 type I-beta1a
def: "A pro-neuregulin-1, membrane-bound isoform that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02297-6 or a 1:1 ortholog thereof." [PMID:12648463, PRO:KRC]
comment: Category=sequence.
synonym: "NRG beta1" RELATED []
synonym: "NRG beta1a" RELATED []
synonym: "NRG1/iso:Ibeta1a" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000029649 ! pro-neuregulin-1, membrane-bound isoform

[Term]
id: PR:000044821
name: neuregulin-1 type I-beta1a mature form (mouse)
def: "A neuregulin-1 type I-beta1a (mouse) that has been proteolytically processed by the Meltrin beta/ADAM19 metalloprotease to produce a soluble form consisting of the ectodomain." [PMID:11116142, PRO:KRC]
comment: Category=organism-modification.
synonym: "mNRG1/iso:Ibeta1a/mature" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG beta1a mature form (mouse)" RELATED []
synonym: "neuregulin beta1a mature form (mouse)" RELATED []
is_a: PR:Q6DR98 ! neuregulin-1 type I-beta1a (mouse)
relationship: output_of GO:0016485 ! protein processing
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q02297-7
name: pro-neuregulin-1, membrane-bound isoform isoform h7 (human)
def: "A pro-neuregulin-1, membrane-bound isoform (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02297-7." [PRO:DNx, UniProtKB:Q02297]
comment: Category=organism-sequence.
synonym: "hNRG1/iso:h7" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform Beta2 (human)" EXACT [UniProtKB:Q02297]
xref: UniProtKB:Q02297-7
is_a: PR:Q02297 ! pro-neuregulin-1, membrane-bound isoform (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q02297-6
name: neuregulin-1 type I-beta1a (human)
def: "A neuregulin-1 type I-beta1a that is encoded in the genome of human." [PRO:CNA, UniProtKB:Q02297]
comment: Category=organism-sequence.
synonym: "hNRG1/iso:6" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform Beta1 (human)" EXACT [UniProtKB:Q02297]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform Beta1A (human)" EXACT [UniProtKB:Q02297]
xref: UniProtKB:Q02297-6
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000044820 ! neuregulin-1 type I-beta1a

[Term]
id: PR:Q02297-4
name: pro-neuregulin-1, membrane-bound isoform isoform h4 (human)
def: "A pro-neuregulin-1, membrane-bound isoform (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02297-4." [PRO:DNx, UniProtKB:Q02297]
comment: Category=organism-sequence.
synonym: "hNRG1/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform Alpha3 (human)" EXACT [UniProtKB:Q02297]
xref: UniProtKB:Q02297-4
is_a: PR:Q02297 ! pro-neuregulin-1, membrane-bound isoform (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q02297-3
name: pro-neuregulin-1, membrane-bound isoform isoform h3 (human)
def: "A pro-neuregulin-1, membrane-bound isoform (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02297-3." [PRO:DNx, UniProtKB:Q02297]
comment: Category=organism-sequence.
synonym: "hNRG1/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform Alpha2B (human)" EXACT [UniProtKB:Q02297]
xref: UniProtKB:Q02297-3
is_a: PR:Q02297 ! pro-neuregulin-1, membrane-bound isoform (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q02297-2
name: pro-neuregulin-1, membrane-bound isoform isoform h2 (human)
def: "A pro-neuregulin-1, membrane-bound isoform (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02297-2." [PRO:DNx, UniProtKB:Q02297]
comment: Category=organism-sequence.
synonym: "hNRG1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform Alpha1A (human)" EXACT [UniProtKB:Q02297]
xref: UniProtKB:Q02297-2
is_a: PR:Q02297 ! pro-neuregulin-1, membrane-bound isoform (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q02297-1
name: pro-neuregulin-1, membrane-bound isoform isoform h1 (human)
def: "A pro-neuregulin-1, membrane-bound isoform (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q02297-1." [PRO:DNx, UniProtKB:Q02297]
comment: Category=organism-sequence.
synonym: "hNRG1/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform Alpha (human)" EXACT [UniProtKB:Q02297]
xref: UniProtKB:Q02297-1
is_a: PR:Q02297 ! pro-neuregulin-1, membrane-bound isoform (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q02297
name: pro-neuregulin-1, membrane-bound isoform (human)
def: "A pro-neuregulin-1, membrane-bound isoform that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q02297]
comment: Category=organism-gene.
synonym: "GGF" RELATED Gene-based [UniProtKB:Q02297]
synonym: "HGL" RELATED Gene-based [UniProtKB:Q02297]
synonym: "NDF" RELATED Gene-based [UniProtKB:Q02297]
synonym: "HRGA" RELATED Gene-based [UniProtKB:Q02297]
synonym: "NRG1" RELATED Gene-based [UniProtKB:Q02297]
synonym: "SMDF" RELATED Gene-based [UniProtKB:Q02297]
synonym: "hNRG1" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-NRG1 (human)" EXACT [UniProtKB:Q02297]
xref: UniProtKB:Q02297
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000029649 ! pro-neuregulin-1, membrane-bound isoform
relationship: has_gene_template HGNC:7997 ! NRG1 (human)

[Term]
id: PR:000044840
name: neuregulin-1 type III (mouse)
def: "A neuregulin-1 (mouse) that has an N-terminal cystein-rich domain (CRD)." [PMID:15044753, PRO:KRC]
comment: Category=union.
synonym: "mNRG1/iso:IIIbeta[1a/1c/3]" EXACT PRO-short-label [PRO:DAN]
is_a: PR:Q6DR99 ! neuregulin-1 (mouse)
union_of: PR:Q3URY7 ! neuregulin-1 type III-beta1c (mouse)
union_of: PR:Q6DR99-1 ! neuregulin-1 type III-beta1a (mouse)
union_of: PR:Q8BX76 ! neuregulin-1 type III-beta3 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044841
name: neuregulin-1 type I-alpha2a (mouse)
def: "A neuregulin-1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein described as NRG type I-alpha2 in PMID:11116142." [PMID:11116142, PRO:KRC]
comment: Category=organism-sequence.
synonym: "NRG-alpha2 (mouse)" RELATED [PMID:11116142]
synonym: "mNRG1/iso:Ialpha2a" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG type I-alpha2a (mouse)" RELATED []
is_a: PR:Q6DR99 ! neuregulin-1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044842
name: neuregulin-1 type I-alpha2a precursor (mouse)
def: "A neuregulin-1 type I-alpha2a (mouse) that is a transmembrane protein which has not been proteolytically processed." [PMID:11116142, PRO:KRC]
comment: Category=organism-modification.
synonym: "mNRG1/iso:Ialpha2a/precursor" EXACT PRO-short-label [PRO:DAN]
synonym: "NRG type I-alpha2a precursor (mouse)" RELATED []
is_a: PR:000044841 ! neuregulin-1 type I-alpha2a (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000044843
name: neuregulin-1 intracellular domain (mouse)
def: "A neuregulin-1 (mouse) that corresponds to the intracellular domain after proteolytic cleavage. UniProtKB:Q6DR99, 326-700." [PMID:20610754, PMID:24083437, PRO:KRC]
comment: Category=organism-modification. Evidence=(ECO:0000205, based on PMID:24083437).
synonym: "NRG1 ICD (mouse)" RELATED []
synonym: "mNRG1/Clv:intracellular" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:Q6DR99, 326-700" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:Q6DR99 ! neuregulin-1 (mouse)
relationship: output_of GO:0016485 ! protein processing
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q6DR99
name: neuregulin-1 (mouse)
def: "A pro-neuregulin-1, membrane-bound isoform that is encoded in the genome of mouse." [OMA:Q6DR99, PRO:DNx]
comment: Category=organism-gene.
synonym: "mNRG1" EXACT PRO-short-label [PRO:DNx]
synonym: "protein Nrg1 (mouse)" EXACT [UniProtKB:Q6DR99]
xref: UniProtKB:Q6DR99
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000029649 ! pro-neuregulin-1, membrane-bound isoform
relationship: has_gene_template MGI:96083 ! Nrg1 (mouse)

[Term]
id: PR:Q6DR98
name: neuregulin-1 type I-beta1a (mouse)
def: "A neuregulin-1 type I-beta1a that is encoded in the genome of mouse." [PMID:11116142, PRO:KRC]
comment: Category=organism-sequence.
synonym: "NRG beta1 (mouse)" RELATED []
synonym: "mNRG1/iso:Ibeta1a" EXACT PRO-short-label [PRO:DAN]
xref: UniProtKB:Q6DR98
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000044820 ! neuregulin-1 type I-beta1a

[Term]
id: PR:P43322-8
name: pro-neuregulin-1, membrane-bound isoform isoform rBeta3 (rat)
def: "A pro-neuregulin-1, membrane-bound isoform (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43322-8." [PRO:DNx, UniProtKB:P43322]
comment: Category=organism-sequence.
synonym: "rNRG1/iso:rBeta3" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform NDF4 (rat)" EXACT [UniProtKB:P43322]
xref: UniProtKB:P43322-8
is_a: PR:P43322 ! pro-neuregulin-1, membrane-bound isoform (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:000029649
name: pro-neuregulin-1, membrane-bound isoform
def: "A protein that is a translation product of the human NRG1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "GGF" RELATED Gene-based []
synonym: "HGL" RELATED Gene-based []
synonym: "NDF" RELATED Gene-based []
synonym: "HRGA" RELATED Gene-based []
synonym: "NRG1" EXACT PRO-short-label [PRO:DNx]
synonym: "SMDF" RELATED Gene-based []
synonym: "pro-NRG1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P43322-6
name: pro-neuregulin-1, membrane-bound isoform isoform rBeta2 (rat)
def: "A pro-neuregulin-1, membrane-bound isoform (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43322-6." [PRO:DNx, UniProtKB:P43322]
comment: Category=organism-sequence.
synonym: "rNRG1/iso:rBeta2" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform NDF40 (rat)" EXACT [UniProtKB:P43322]
xref: UniProtKB:P43322-6
is_a: PR:P43322 ! pro-neuregulin-1, membrane-bound isoform (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P43322-7
name: pro-neuregulin-1, membrane-bound isoform isoform rBetA2A (rat)
def: "A pro-neuregulin-1, membrane-bound isoform (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43322-7." [PRO:DNx, UniProtKB:P43322]
comment: Category=organism-sequence.
synonym: "rNRG1/iso:rBetA2A" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform NDF22 (rat)" EXACT [UniProtKB:P43322]
xref: UniProtKB:P43322-7
is_a: PR:P43322 ! pro-neuregulin-1, membrane-bound isoform (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P43322-4
name: pro-neuregulin-1, membrane-bound isoform isoform rAlpha2C (rat)
def: "A pro-neuregulin-1, membrane-bound isoform (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43322-4." [PRO:DNx, UniProtKB:P43322]
comment: Category=organism-sequence.
synonym: "rNRG1/iso:rAlpha2C" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform NDF44 (rat)" EXACT [UniProtKB:P43322]
xref: UniProtKB:P43322-4
is_a: PR:P43322 ! pro-neuregulin-1, membrane-bound isoform (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P43322-5
name: neuregulin-1 type I-beta1a (rat)
def: "A neuregulin-1 type I-beta1a that is encoded in the genome of rat." [PRO:CNA, UniProtKB:P43322]
comment: Category=organism-sequence.
synonym: "rNRG1/iso:Ibeta1a" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P43322-5
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000044820 ! neuregulin-1 type I-beta1a

[Term]
id: PR:P43322-2
name: pro-neuregulin-1, membrane-bound isoform isoform rAlpha2A (rat)
def: "A pro-neuregulin-1, membrane-bound isoform (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43322-2." [PRO:DNx, UniProtKB:P43322]
comment: Category=organism-sequence.
synonym: "rNRG1/iso:rAlpha2A" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform NDF38 (rat)" EXACT [UniProtKB:P43322]
xref: UniProtKB:P43322-2
is_a: PR:P43322 ! pro-neuregulin-1, membrane-bound isoform (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P43322-3
name: pro-neuregulin-1, membrane-bound isoform isoform rAlpha2B (rat)
def: "A pro-neuregulin-1, membrane-bound isoform (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43322-3." [PRO:DNx, UniProtKB:P43322]
comment: Category=organism-sequence.
synonym: "rNRG1/iso:rAlpha2B" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform NDF19 (rat)" EXACT [UniProtKB:P43322]
xref: UniProtKB:P43322-3
is_a: PR:P43322 ! pro-neuregulin-1, membrane-bound isoform (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:P43322-1
name: pro-neuregulin-1, membrane-bound isoform isoform rBeta4 (rat)
def: "A pro-neuregulin-1, membrane-bound isoform (rat) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P43322-1." [PRO:DNx, UniProtKB:P43322]
comment: Category=organism-sequence.
synonym: "rNRG1/iso:rBeta4" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform NDF42A (rat)" EXACT [UniProtKB:P43322]
xref: UniProtKB:P43322-1
is_a: PR:P43322 ! pro-neuregulin-1, membrane-bound isoform (rat)
relationship: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus

[Term]
id: PR:Q05199-3
name: pro-neuregulin-1, membrane-bound isoform isoform 3 (chicken)
def: "A pro-neuregulin-1, membrane-bound isoform (chicken) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q05199-3." [PRO:DNx, UniProtKB:Q05199]
comment: Category=organism-sequence.
synonym: "chick-NRG1/iso:3" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-neuregulin-1, membrane-bound isoform isoform CRD-NRG-BETA2A (chicken)" EXACT [UniProtKB:Q05199]
xref: UniProtKB:Q05199-3
is_a: PR:Q05199 ! pro-neuregulin-1, membrane-bound isoform (chicken)
relationship: only_in_taxon NCBITaxon:9031 ! Gallus gallus

[Term]
id: PR:Q05199
name: pro-neuregulin-1, membrane-bound isoform (chicken)
def: "A pro-neuregulin-1, membrane-bound isoform that is encoded in the genome of chicken." [OMA:Q05199, PRO:DNx]
comment: Category=organism-gene.
synonym: "ARIA" RELATED Gene-based [UniProtKB:Q05199]
synonym: "NRG1" RELATED Gene-based [UniProtKB:Q05199]
synonym: "chick-NRG1" EXACT PRO-short-label [PRO:DNx]
synonym: "pro-NRG1 (chicken)" EXACT [UniProtKB:Q05199]
xref: UniProtKB:Q05199
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000029649 ! pro-neuregulin-1, membrane-bound isoform
relationship: has_gene_template NCBIGene:373906 ! NRG1 (chicken)