[Term]
id: PR:Q91XQ0-2
name: dynein axonemal heavy chain 8 isoform 2 (mouse)
def: "A dynein axonemal heavy chain 8 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q91XQ0-2." [PMID:12297094, PRO:KRC]
comment: Category=organism-sequence. Note: PMID:12297094 demonstrates the existence of at least two alternatively spliced, testis-specific Dnahc8 mRNAs transcribed from both the wild type and the mutant t allele.
synonym: "mDNAH8/iso:2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q91XQ0-2
is_a: PR:Q91XQ0 ! dynein axonemal heavy chain 8 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q91XQ0-1
name: dynein axonemal heavy chain 8 isoform 1 (mouse)
def: "A dynein axonemal heavy chain 8 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q91XQ0-1." [PMID:12297094, PMID:16054618, PRO:KRC]
comment: Category=organism-sequence. Note: PMID:16054618, a combination of affinity-purified polyclonal antisera generated against epitopes from various parts of the longest possible Dnah8 coding region were used to determine that the only significant form in testis and spermatozoa is the longest form (isoform 1). Some of the profusion of mRNA species is due to variation of the 5'-UTR that does not change the coding sequence. PMID:12297094 demonstrates the existence of at least two alternatively spliced, testis-specific Dnahc8 mRNAs transcribed from both the wild type and the mutant t allele.
synonym: "mDNAH8/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q91XQ0-1
is_a: PR:Q91XQ0 ! dynein axonemal heavy chain 8 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000029434
name: dynein axonemal heavy chain 8
def: "A protein that is a translation product of the human DNAH8 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "DNAH8" EXACT PRO-short-label [PRO:DNx]
synonym: "Dnahc8" RELATED Gene-based [PRO:DNx]
synonym: "ciliary dynein heavy chain 8" BROAD [PRO:DNx]
synonym: "dynein heavy chain 8, axonemal" EXACT []
synonym: "axonemal beta dynein heavy chain 8" BROAD [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:Q91XQ0
name: dynein axonemal heavy chain 8 (mouse)
def: "A dynein axonemal heavy chain 8 that is encoded in the genome of mouse." [OMA:Q91XQ0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Dnah8" RELATED Gene-based [UniProtKB:Q91XQ0]
synonym: "Dnahc8" RELATED Gene-based [UniProtKB:Q91XQ0]
synonym: "mDNAH8" EXACT PRO-short-label [PRO:DNx]
synonym: "ciliary dynein heavy chain 8 (mouse)" EXACT [UniProtKB:Q91XQ0]
synonym: "axonemal beta dynein heavy chain 8 (mouse)" EXACT [UniProtKB:Q91XQ0]
xref: UniProtKB:Q91XQ0
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000029434 ! dynein axonemal heavy chain 8
relationship: has_gene_template MGI:107714 ! Dnah8 (mouse)