[Term]
id: PR:000028678
name: ticam2:activated TLR4 complex (human)
def: "A ticam2:activated TLR4 complex whose components are encoded in the genome of human." [Reactome:R-HSA-166163]
comment: Category=organism-complex.
synonym: "TRAM:activated TLR4 (human)" EXACT [Reactome:R-HSA-166163]
synonym: "TRAM:TLR4:MD2:LPS:CD14 (human)" EXACT [Reactome:R-HSA-166163]
xref: Reactome:R-HSA-166163 "PR:000028678 located_in GO:0010008"
is_a: PR:000027202 ! ticam2:activated TLR4 complex
relationship: has_component CHEBI:16412 {cardinality="2"} ! lipopolysaccharide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_component PR:000025786 {cardinality="2"} ! lymphocyte antigen 96 isoform 1, signal peptide removed N-glycosylated 1 (human)
relationship: has_component PR:000025787 {cardinality="2"} ! Toll-like receptor 4 isoform 1, signal peptide removed N-glycosylated 1 (human)
relationship: has_component PR:000040891 {cardinality="2"} ! TIR domain-containing adapter molecule 2 isoform 1, initiator methionine removed myristoylated and phosphorylated 1 (human)