[Term]
id: PR:000028434
name: TRAF2:TRADD:RIP1 complex (human)
def: "A death-inducing signaling complex that is composed of three molecules of TNF receptor-associated factor 2, initiator methionine removed form (human), one molecule of receptor-interacting serine/threonine-protein kinase 1 (human), and three molecules of tumor necrosis factor receptor type 1-associated DEATH domain protein (human)." [PRO:DAN, PRO:PDE, Reactome:R-HSA-140935]
comment: Category=organism-complex.
xref: Reactome:R-HSA-140935 "PR:000028434 located_in GO:0005829"
is_a: GO:0031264 ! death-inducing signaling complex
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: has_component PR:000028382 {cardinality="3"} ! TNF receptor-associated factor 2, initiator methionine removed form (human)
relationship: has_component PR:Q13546 {cardinality="1"} ! receptor-interacting serine/threonine-protein kinase 1 (human)
relationship: has_component PR:Q15628 {cardinality="3"} ! tumor necrosis factor receptor type 1-associated DEATH domain protein (human)