[Term]
id: PR:O35876
name: survival motor neuron protein (rat)
def: "A survival motor neuron protein that is encoded in the genome of rat." [PANTHER:PTHR12664:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Smn" RELATED Gene-based [UniProtKB:O35876]
synonym: "Smn1" RELATED Gene-based [UniProtKB:O35876]
synonym: "rSMN" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O35876
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000026269 ! survival motor neuron protein
relationship: has_gene_template RGD:620755 ! Smn1 (rat)

[Term]
id: PR:Q98SU9
name: survival motor neuron protein (chicken)
def: "A survival motor neuron protein that is encoded in the genome of chicken." [OMA:Q98SU9, PRO:DNx]
comment: Category=organism-gene.
synonym: "chick-SMN" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q98SU9
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000026269 ! survival motor neuron protein
relationship: has_gene_template NCBIGene:374025 ! SMN (chicken)

[Term]
id: PR:Q9VV74
name: survival motor neuron protein (fruit fly)
def: "A survival motor neuron protein that is encoded in the genome of fruit fly." [OMA:Q9VV74, PANTHER:PTHR12664:SF0, PRO:DNx]
comment: Category=organism-gene.
synonym: "Smn" RELATED Gene-based [UniProtKB:Q9VV74]
synonym: "CG16725" RELATED Gene-based [UniProtKB:Q9VV74]
synonym: "fly-SMN" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9VV74
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000026269 ! survival motor neuron protein
relationship: has_gene_template FlyBase:FBgn0036641 ! Smn (fruit fly)

[Term]
id: PR:Q16637
name: survival motor neuron protein (human)
def: "A survival motor neuron protein that is encoded in the genome of human." [PRO:DAN, UniProtKB:Q16637]
comment: Category=organism-gene. Note: The SMN1 and SMN2 genes encode identical proteins.
synonym: "SMN" RELATED Gene-based [UniProtKB:Q16637]
synonym: "SMN1" RELATED Gene-based [UniProtKB:Q16637]
synonym: "SMN2" RELATED Gene-based [UniProtKB:Q16637]
synonym: "SMNC" RELATED Gene-based [UniProtKB:Q16637]
synonym: "SMNT" RELATED Gene-based [UniProtKB:Q16637]
synonym: "hSMN" EXACT PRO-short-label [PRO:DAN]
synonym: "gemin-1 (human)" EXACT [UniProtKB:Q16637]
synonym: "component of gems 1 (human)" EXACT [UniProtKB:Q16637]
xref: UniProtKB:Q16637
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026269 ! survival motor neuron protein
relationship: has_gene_template HGNC:11117 ! SMN1 (human)
relationship: has_gene_template HGNC:11118 ! SMN2 (human)

[Term]
id: PR:P97801
name: survival motor neuron protein (mouse)
def: "A survival motor neuron protein that is encoded in the genome of mouse." [OMA:P97801, PRO:DNx]
comment: Category=organism-gene.
synonym: "Smn" RELATED Gene-based [UniProtKB:P97801]
synonym: "Smn1" RELATED Gene-based [UniProtKB:P97801]
synonym: "mSMN" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P97801
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000026269 ! survival motor neuron protein
relationship: has_gene_template MGI:109257 ! Smn1 (mouse)

[Term]
id: PR:Q9W6S8
name: survival motor neuron protein 1 (zebrafish)
def: "A survival motor neuron protein that is encoded in the genome of zebrafish." [OMA:Q9W6S8, PRO:DNx]
comment: Category=organism-gene.
synonym: "smn" RELATED Gene-based [UniProtKB:Q9W6S8]
synonym: "smn1" RELATED Gene-based [UniProtKB:Q9W6S8]
synonym: "z-SMN" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9W6S8
intersection_of: only_in_taxon NCBITaxon:7955 ! Danio rerio
intersection_of: PR:000026269 ! survival motor neuron protein
relationship: has_gene_template ZFIN:ZDB-GENE-990715-16 ! smn1 (zebrafish)

[Term]
id: PR:Q16637-3
name: survival motor neuron protein isoform 3 (human)
def: "A survival motor neuron protein isoform 3 that is encoded in the genome of human." [PMID:15494309]
comment: Category=organism-sequence.
synonym: "hSMN/iso:3" EXACT PRO-short-label [PRO:DNx]
synonym: "SMN-delta7 (human)" EXACT []
xref: UniProtKB:Q16637-3
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026276 ! survival motor neuron protein isoform 3

[Term]
id: PR:000049296
name: survival motor neuron protein, initiator methionine removed form (human)
def: "A survival motor neuron protein (human) that has had the initiator methionine removed. UniProtKB:Q16637, 2-294." [PRO:DNx, Reactome:R-HSA-191839, Reactome:R-HSA-191892]
comment: Category=organism-modification.
synonym: "hSMN/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000218903" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q16637, 2-294" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-191839 "PR:000049296 located_in GO:0005829"
xref: Reactome:R-HSA-191892 "PR:000049296 located_in GO:0005654"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q16637 ! survival motor neuron protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16637-4
name: survival motor neuron protein isoform hSMN-delta57 (human)
def: "A survival motor neuron protein (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16637-4." [PRO:DNx, UniProtKB:Q16637]
comment: Category=organism-sequence.
synonym: "hSMN/iso:hSMN-delta57" EXACT PRO-short-label [PRO:DNx]
synonym: "survival motor neuron protein isoform Iso57-SMN (human)" EXACT [UniProtKB:Q16637]
xref: UniProtKB:Q16637-4
is_a: PR:Q16637 ! survival motor neuron protein (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000026269
name: survival motor neuron protein
def: "A protein that is a translation product of the human SMN1 or SMN2 genes, 1:1 orthologs thereof, or a semi-ortholog thereof." [PRO:DAN]
comment: Category=gene. Note: The human SMN1 and SMN2 genes encode identical proteins.
synonym: "SMN" EXACT PRO-short-label [PRO:DAN]
synonym: "SMN1" RELATED Gene-based []
synonym: "SMN2" RELATED Gene-based []
synonym: "SMNC" RELATED Gene-based []
synonym: "SMNT" RELATED Gene-based []
synonym: "Gemin-1" EXACT []
synonym: "Component of gems 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q16637-1
name: survival motor neuron protein isoform 1 (human)
def: "A survival motor neuron protein isoform 1 that is encoded in the genome of human." [PRO:CNx]
comment: Category=organism-sequence.
synonym: "full-SMN" RELATED []
synonym: "hSMN/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16637-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026270 ! survival motor neuron protein isoform 1

[Term]
id: PR:Q16637-2
name: survival motor neuron protein isoform 2 (human)
def: "A survival motor neuron protein isoform 2 that is encoded in the genome of human." [PRO:CNx]
comment: Category=organism-sequence.
synonym: "hSMN/iso:2" EXACT PRO-short-label [PRO:DNx]
synonym: "SMN-delta5 (human)" EXACT []
xref: UniProtKB:Q16637-2
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000026273 ! survival motor neuron protein isoform 2

[Term]
id: PR:000026714
name: survival motor neuron protein, initiator methionine removed form
def: "A survival motor neuron protein that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "SMN/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:000026269 ! survival motor neuron protein

[Term]
id: PR:000026273
name: survival motor neuron protein isoform 2
def: "A survival motor neuron protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16637-2 or a 1:1 ortholog thereof." [PRO:CNx]
comment: Category=sequence.
synonym: "SMN/iso:2" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000026269 ! survival motor neuron protein

[Term]
id: PR:000026715
name: survival motor neuron protein isoform 1, initiator methionine removed form
def: "A survival motor neuron protein isoform 1 that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "SMN/iso:1/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:000026270 ! survival motor neuron protein isoform 1

[Term]
id: PR:000026270
name: survival motor neuron protein isoform 1
def: "A survival motor neuron protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16637-1 or a 1:1 ortholog thereof." [PRO:CNx]
comment: Category=sequence.
synonym: "SMN/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000026269 ! survival motor neuron protein

[Term]
id: PR:000026276
name: survival motor neuron protein isoform 3
def: "A survival motor neuron protein that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16637-3 or a 1:1 ortholog thereof." [PRO:CNx]
comment: Category=sequence.
synonym: "SMN/iso:3" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000026269 ! survival motor neuron protein