[Term]
id: PR:P76340
name: transcriptional regulatory protein HprR (Escherichia coli K-12)
def: "A transcriptional regulatory protein yedW that is encoded in the genome of Escherichia coli K-12." []
comment: Category=organism-gene.
synonym: "hprR" RELATED Gene-based [UniProtKB:P76340]
synonym: "yedW" RELATED Gene-based [UniProtKB:P76340]
synonym: "b1969" RELATED Gene-based [UniProtKB:P76340]
synonym: "JW5322" RELATED Gene-based [UniProtKB:P76340]
synonym: "Ec-yedW" EXACT PRO-short-label [PRO:DNx]
synonym: "hydrogen peroxide response regulator (Escherichia coli K-12)" EXACT [UniProtKB:P76340]
xref: EcoCyc:G7057-MONOMER
xref: UniProtKB:P76340
intersection_of: only_in_taxon NCBITaxon:83333 ! Escherichia coli K-12
intersection_of: PR:000025088 ! transcriptional regulatory protein yedW
relationship: has_gene_template EcoGene:EG14045 ! yedW (Escherichia coli K-12)

[Term]
id: PR:000025089
name: transcriptional regulatory protein yedW isoform 1
def: "A transcriptional regulatory protein yedW that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P76340-1 or a 1:1 ortholog thereof." [PRO:CNA]
comment: Category=sequence.
synonym: "yedW/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000025088 ! transcriptional regulatory protein yedW

[Term]
id: PR:000025088
name: transcriptional regulatory protein yedW
def: "A protein that is a translation product of the Escherichia coli K-12 yedW gene or a 1:1 ortholog thereof. YedV and yedW are predicted to function as a histidine kinase/response regulator pair of a two-component signal transduction system. The cytoplasmic histidine kinase domain of YedV was purified and showed autocatalytic self-phosphorylation activity. A small amount of trans-phosphorylation of YedW and non-cognate response regulators was also observed." [EcoCyc:G7057-MONOMER]
comment: Category=gene.
synonym: "yedW" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:000036717
name: transcriptional regulatory protein yedW isoform 1 phosphorylated 1 (Escherichia coli K-12)
def: "A transcriptional regulatory protein yedW isoform 1 phosphorylated 1 in Escherichia coli K-12. UniProtKB:P76340-1, Asp-51, MOD:00042." [EcoCyc:G7057-MONOMER, PRO:CNA, UniProtKB:P76340]
comment: Category=organism-modification. Evidence=(ECO:0000255, for modified site, based on UniProtKB:P76340).
synonym: "YedW-P" BROAD [PRO:DNx]
synonym: "Ec-yedW/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P76340-1, Asp-51, MOD:00042" EXACT PRO-proteoform-std [PRO:DAN]
intersection_of: only_in_taxon NCBITaxon:83333 ! Escherichia coli K-12
intersection_of: PR:000025091 ! transcriptional regulatory protein yedW isoform 1 phosphorylated 1
relationship: has_part MOD:00042 ! L-aspartic 4-phosphoric anhydride

[Term]
id: PR:P76340-1
name: transcriptional regulatory protein YedW isoform 1 (Escherichia coli K-12)
def: "A transcriptional regulatory protein yedW isoform 1 that is encoded in the genome of Escherichia coli K-12." [PRO:CNA]
comment: Category=organism-sequence.
synonym: "Ec-yedW/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P76340-1
intersection_of: only_in_taxon NCBITaxon:83333 ! Escherichia coli K-12
intersection_of: PR:000025089 ! transcriptional regulatory protein yedW isoform 1

[Term]
id: PR:000025090
name: transcriptional regulatory protein yedW isoform 1 unmodified form
def: "A transcriptional regulatory protein yedW isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [EcoCyc:G7057-MONOMER]
comment: Category=modification.
synonym: "yedW/iso:1/UnMod" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part PR:000021935 ! immature protein part
intersection_of: PR:000025089 ! transcriptional regulatory protein yedW isoform 1
intersection_of: lacks_part PR:000025513 ! modified amino-acid residue
disjoint_from: PR:000018264 ! proteolytic cleavage product

[Term]
id: PR:000025091
name: transcriptional regulatory protein yedW isoform 1 phosphorylated 1
def: "A transcriptional regulatory protein yedW isoform 1 that has been phosphorylated by phosphorylated yedV on an Asp residue within the receiver domain. Example: UniProtKB:P76340-1, Asp-51, MOD:00042." [EcoCyc:G7057-MONOMER, PMID:15522865]
comment: Category=modification.
synonym: "yedW/iso:1/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000025089 ! transcriptional regulatory protein yedW isoform 1
relationship: has_part MOD:00042 ! L-aspartic 4-phosphoric anhydride