[Term]
id: PR:P0A853-1
name: tryptophanase isoform 1 (Escherichia coli K-12)
def: "A tryptophanase isoform 1 that is encoded in the genome of Escherichia coli K-12." [PRO:DNx, UniProtKB:P0A853]
comment: Category=organism-sequence.
synonym: "Ec-tnaA/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P0A853-1
intersection_of: only_in_taxon NCBITaxon:83333 ! Escherichia coli K-12
intersection_of: PR:000025239 ! tryptophanase isoform 1

[Term]
id: PR:000025239
name: tryptophanase isoform 1
def: "A tryptophanase that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P0A853-1 or a 1:1 ortholog thereof." [EcoCyc:TRYPTOPHAN-MONOMER]
comment: Category=sequence.
synonym: "tnaA/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000024075 ! tryptophanase

[Term]
id: PR:000024075
name: tryptophanase
def: "A protein that is a translation product of the Escherichia coli K-12 tnaA gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ind" RELATED []
synonym: "tnaA" EXACT PRO-short-label [PRO:DNx]
synonym: "TNase" EXACT []
synonym: "L-tryptophan indole-lyase" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000036760
name: tryptophanase isoform 1 pyridoxal phosphate lysine 1 (Escherichia coli K-12)
def: "A tryptophanase isoform 1 pyridoxal phosphate lysine 1 in Escherichia coli K-12. UniProtKB:P0A853-1, Lys-270, MOD:00128." [PRO:CNA]
comment: Category=organism-modification.
synonym: "Ec-tnaA/iso:1/Pyrdox:1" EXACT PRO-short-label [PRO:DAN]
synonym: "UniProtKB:P0A853-1, Lys-270, MOD:00128" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:83333 ! Escherichia coli K-12
intersection_of: PR:000025242 ! tryptophanase isoform 1 pyridoxal phosphate lysine 1
relationship: has_part MOD:00128 ! N6-pyridoxal phosphate-L-lysine

[Term]
id: PR:000036759
name: tryptophanase isoform 1 acetylated 1 (Escherichia coli K-12)
def: "A tryptophanase isoform 1 acetylated 1 in Escherichia coli K-12. UniProtKB:P0A853-1, Lys-5/Lys-115/Lys-156/Lys-450, MOD:00064." [EcoCyc:TRYPTOPHAN-MONOMER, PRO:CNA]
comment: Category=organism-modification.
synonym: "Ec-tnaA/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P0A853-1, Lys-5/Lys-115/Lys-156/Lys-450, MOD:00064" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:83333 ! Escherichia coli K-12
intersection_of: PR:000025241 ! tryptophanase isoform 1 acetylated 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:P0A853
name: tryptophanase (Escherichia coli K-12)
def: "A tryptophanase that is encoded in the genome of Escherichia coli K-12." [PRO:DNx, UniProtKB:P0A853]
comment: Category=organism-gene.
synonym: "ind" RELATED Gene-based [UniProtKB:P0A853]
synonym: "tnaA" RELATED Gene-based [UniProtKB:P0A853]
synonym: "b3708" RELATED Gene-based [UniProtKB:P0A853]
synonym: "JW3686" RELATED Gene-based [UniProtKB:P0A853]
synonym: "Ec-tnaA" EXACT PRO-short-label [PRO:DNx]
synonym: "TNase (Escherichia coli K-12)" EXACT [UniProtKB:P0A853]
synonym: "L-tryptophan indole-lyase (Escherichia coli K-12)" EXACT [UniProtKB:P0A853]
xref: EcoCyc:TRYPTOPHAN-MONOMER
xref: UniProtKB:P0A853
intersection_of: only_in_taxon NCBITaxon:83333 ! Escherichia coli K-12
intersection_of: PR:000024075 ! tryptophanase
relationship: has_gene_template EcoGene:EG11005 ! tnaA (Escherichia coli K-12)

[Term]
id: PR:000025242
name: tryptophanase isoform 1 pyridoxal phosphate lysine 1
def: "A tryptophanase isoform 1 that has pyridoxal 5'-phosphate covalently bound to the active site Lys residue at the position equivalent to Lys-270 of the amino acid sequence represented by UniProtKB:P0A853-1. Example: UniProtKB:P0A853-1, Lys-270, MOD:00128." [PMID:16790938]
comment: Category=modification.
synonym: "tnaA/iso:1/Pyrdox:1" EXACT PRO-short-label [PRO:DAN]
is_a: PR:000025239 ! tryptophanase isoform 1
relationship: has_part MOD:00128 ! N6-pyridoxal phosphate-L-lysine

[Term]
id: PR:000025241
name: tryptophanase isoform 1 acetylated 1
def: "A tryptophanase isoform 1 that has been post-translationally modified to include N6-acetyllysine residues. Example: UniProtKB:P0A853-1, Lys-5/Lys-115/Lys-156/Lys-450, MOD:00064." [EcoCyc:TRYPTOPHAN-MONOMER]
comment: Category=modification.
synonym: "tnaA/iso:1/Ac:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000025239 ! tryptophanase isoform 1
relationship: has_part MOD:00064 ! N6-acetyl-L-lysine

[Term]
id: PR:000025240
name: tryptophanase isoform 1 unmodified form
def: "A tryptophanase isoform 1 that has not been subjected to any co- or post-translational residue modification or peptide bond cleavage." [EcoCyc:TRYPTOPHAN-MONOMER]
comment: Category=modification.
synonym: "tnaA/iso:1/UnMod" EXACT PRO-short-label [PRO:DNx]
intersection_of: has_part PR:000021935 ! immature protein part
intersection_of: PR:000025239 ! tryptophanase isoform 1
intersection_of: lacks_part PR:000025513 ! modified amino-acid residue
disjoint_from: PR:000018264 ! proteolytic cleavage product