[Term]
id: PR:P24186
name: bifunctional protein FolD (Escherichia coli K-12)
def: "A bifunctional protein FolD that is encoded in the genome of Escherichia coli K-12." [PRO:DNx, UniProtKB:P24186]
comment: Category=organism-gene.
synonym: "ads" RELATED Gene-based [UniProtKB:P24186]
synonym: "folD" RELATED Gene-based [UniProtKB:P24186]
synonym: "b0529" RELATED Gene-based [UniProtKB:P24186]
synonym: "JW0518" RELATED Gene-based [UniProtKB:P24186]
synonym: "Ec-folD" EXACT PRO-short-label [PRO:DNx]
xref: EcoCyc:FOLD-MONOMER
xref: UniProtKB:P24186
intersection_of: only_in_taxon NCBITaxon:83333 ! Escherichia coli K-12
intersection_of: PR:000022679 ! bifunctional protein FolD
relationship: has_gene_template EcoGene:EG10328 ! folD (Escherichia coli K-12)

[Term]
id: PR:Q04448-2
name: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform A (fruit fly)
def: "A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04448-2." [PRO:DNx, UniProtKB:Q04448]
comment: Category=organism-sequence.
synonym: "fly-folD/iso:A" EXACT PRO-short-label [PRO:DNx]
synonym: "bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform Hedengren-B (fruit fly)" EXACT [UniProtKB:Q04448]
xref: UniProtKB:Q04448-2
is_a: PR:Q04448 ! bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:Q04448-1
name: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform B (fruit fly)
def: "A bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q04448-1." [PRO:DNx, UniProtKB:Q04448]
comment: Category=organism-sequence.
synonym: "fly-folD/iso:B" EXACT PRO-short-label [PRO:DNx]
synonym: "bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial isoform Hedengren-A (fruit fly)" EXACT [UniProtKB:Q04448]
xref: UniProtKB:Q04448-1
is_a: PR:Q04448 ! bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:000022679
name: bifunctional protein FolD
def: "A protein that is a translation product of the Escherichia coli K-12 folD gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ads" RELATED []
synonym: "folD" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000000001 ! protein

[Term]
id: PR:Q2FZJ6
name: bifunctional protein FolD (Staphylococcus aureus subsp. aureus NCTC 8325)
def: "A bifunctional protein FolD that is encoded in the genome of Staphylococcus aureus subsp. aureus NCTC 8325." [OMA:Q2FZJ6, PRO:DNx]
comment: Category=organism-gene.
synonym: "folD" RELATED Gene-based [UniProtKB:Q2FZJ6]
synonym: "folD (STAA8)" EXACT PRO-short-label [PRO:DNx]
synonym: "SAOUHSC_01007" RELATED Gene-based [UniProtKB:Q2FZJ6]
xref: UniProtKB:Q2FZJ6
intersection_of: only_in_taxon NCBITaxon:93061 ! Staphylococcus aureus subsp. aureus NCTC 8325
intersection_of: PR:000022679 ! bifunctional protein FolD
relationship: has_gene_template EnsemblBacteria:SAOUHSC_01007 ! folD (Staphylococcus aureus subsp. aureus NCTC 8325)

[Term]
id: PR:Q02046
name: methylenetetrahydrofolate dehydrogenase [NAD(+)] (yeast)
def: "A bifunctional protein FolD that is encoded in the genome of yeast." [OMA:Q02046, PRO:DNx]
comment: Category=organism-gene.
synonym: "MTD1" RELATED Gene-based [UniProtKB:Q02046]
synonym: "yfolD" EXACT PRO-short-label [PRO:DNx]
synonym: "YKR400" RELATED Gene-based [UniProtKB:Q02046]
synonym: "YKR080W" RELATED Gene-based [UniProtKB:Q02046]
xref: UniProtKB:Q02046
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000022679 ! bifunctional protein FolD
relationship: has_gene_template SGD:S000001788 ! MTD1 (yeast)

[Term]
id: PR:Q04448
name: bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (fruit fly)
def: "A bifunctional protein FolD that is encoded in the genome of fruit fly." [OMA:Q04448, PRO:DNx]
comment: Category=organism-gene.
synonym: "Nmdmc" RELATED Gene-based [UniProtKB:Q04448]
synonym: "CG18466" RELATED Gene-based [UniProtKB:Q04448]
synonym: "fly-folD" EXACT PRO-short-label [PRO:DNx]
synonym: "DNMDMC (fruit fly)" EXACT [UniProtKB:Q04448]
xref: UniProtKB:Q04448
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000022679 ! bifunctional protein FolD
relationship: has_gene_template FlyBase:FBgn0010222 ! Nmdmc (fruit fly)

[Term]
id: PR:Q54RI8
name: methenyl tetrahydrofolate cyclohydrolase / NADP-dependent methylene H4F dehydrogenase (Dictyostelium discoideum)
def: "A bifunctional protein FolD that is encoded in the genome of Dictyostelium discoideum." [PRO:DNx]
comment: Category=organism-gene.
synonym: "Dicty-folD" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q54RI8
intersection_of: only_in_taxon NCBITaxon:44689 ! Dictyostelium discoideum
intersection_of: PR:000022679 ! bifunctional protein FolD
relationship: has_gene_template dictyBase:DDB_G0283121 ! DDB_G0283121 (Dictyostelium discoideum)

[Term]
id: PR:A5I112
name: bifunctional protein FolD (Clostridium botulinum A str. Hall)
def: "A bifunctional protein FolD that is encoded in the genome of Clostridium botulinum A str. Hall." [OMA:A5I112, PRO:DNx]
comment: Category=organism-gene. Note: Additional NCBIGenes (GeneIDs) listed in the UniProtKB entry have been reviewed and removed by PRO:DNx.
synonym: "folD" RELATED Gene-based [UniProtKB:A5I112]
synonym: "CBO1172" RELATED Gene-based [UniProtKB:A5I112]
synonym: "CLC_1215" RELATED Gene-based [UniProtKB:A5I112]
synonym: "folD (CLOBH)" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:A5I112
intersection_of: only_in_taxon NCBITaxon:441771 ! Clostridium botulinum A str. Hall
intersection_of: PR:000022679 ! bifunctional protein FolD
relationship: has_gene_template NCBIGene:5400489 ! folD (Clostridium botulinum A str. Hall)

[Term]
id: PR:000024435
name: bifunctional protein FolD, initiator methionine removed form
def: "A bifunctional protein FolD that has had the initiator methionine removed." [PRO:DNx]
comment: Category=modification.
synonym: "folD/InitMet-" EXACT PRO-short-label [PRO:DNx]
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:000022679 ! bifunctional protein FolD