[Term]
id: PR:P40383
name: 5'-3' exoribonuclease 1 (Schizosaccharomyces pombe 972h-)
def: "A 5'-3' exoribonuclease 1 that is encoded in the genome of Schizosaccharomyces pombe 972h-." [OMA:P40383, PANTHER:PTHR12341:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "exo2" RELATED Gene-based [UniProtKB:P40383]
synonym: "SPAC17A5.14" RELATED Gene-based [UniProtKB:P40383]
synonym: "Spom972h-XRN1" EXACT PRO-short-label [PRO:DNx]
synonym: "p140 (Schizosaccharomyces pombe 972h-)" BROAD [UniProtKB:P40383]
synonym: "Exo II (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P40383]
synonym: "exonuclease 2 (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P40383]
synonym: "exonuclease II (Schizosaccharomyces pombe 972h-)" EXACT [UniProtKB:P40383]
xref: UniProtKB:P40383
intersection_of: only_in_taxon NCBITaxon:284812 ! Schizosaccharomyces pombe 972h-
intersection_of: PR:000017511 ! 5'-3' exoribonuclease 1
relationship: has_gene_template PomBase:SPAC17A5.14 ! exo2 (Schizosaccharomyces pombe)

[Term]
id: PR:Q8IZH2-3
name: 5'-3' exoribonuclease 1 isoform h3 (human)
def: "A 5'-3' exoribonuclease 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IZH2-3." [PRO:DNx, UniProtKB:Q8IZH2]
comment: Category=organism-sequence.
synonym: "hXRN1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IZH2-3
is_a: PR:Q8IZH2 ! 5'-3' exoribonuclease 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P97789-2
name: 5'-3' exoribonuclease 1 isoform m2 (mouse)
def: "A 5'-3' exoribonuclease 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97789-2." [PRO:DNx, UniProtKB:P97789]
comment: Category=organism-sequence.
synonym: "mXRN1/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P97789-2
is_a: PR:P97789 ! 5'-3' exoribonuclease 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P97789-3
name: 5'-3' exoribonuclease 1 isoform m3 (mouse)
def: "A 5'-3' exoribonuclease 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97789-3." [PRO:DNx, UniProtKB:P97789]
comment: Category=organism-sequence.
synonym: "mXRN1/iso:m3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P97789-3
is_a: PR:P97789 ! 5'-3' exoribonuclease 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P97789-1
name: 5'-3' exoribonuclease 1 isoform m1 (mouse)
def: "A 5'-3' exoribonuclease 1 (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P97789-1." [PRO:DNx, UniProtKB:P97789]
comment: Category=organism-sequence.
synonym: "mXRN1/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P97789-1
is_a: PR:P97789 ! 5'-3' exoribonuclease 1 (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q8IZH2
name: 5'-3' exoribonuclease 1 (human)
def: "A 5'-3' exoribonuclease 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8IZH2]
comment: Category=organism-gene.
synonym: "SEP1" RELATED Gene-based [UniProtKB:Q8IZH2]
synonym: "XRN1" RELATED Gene-based [UniProtKB:Q8IZH2]
synonym: "hXRN1" EXACT PRO-short-label [PRO:DNx]
synonym: "strand-exchange protein 1 homolog (human)" EXACT [UniProtKB:Q8IZH2]
xref: UniProtKB:Q8IZH2
xref: Reactome:R-HSA-429835 "PR:Q8IZH2 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000017511 ! 5'-3' exoribonuclease 1
relationship: has_gene_template HGNC:30654 ! XRN1 (human)

[Term]
id: PR:P97789
name: 5'-3' exoribonuclease 1 (mouse)
def: "A 5'-3' exoribonuclease 1 that is encoded in the genome of mouse." [OMA:P97789, PRO:DNx]
comment: Category=organism-gene.
synonym: "Exo" RELATED Gene-based [UniProtKB:P97789]
synonym: "Dhm2" RELATED Gene-based [UniProtKB:P97789]
synonym: "Sep1" RELATED Gene-based [UniProtKB:P97789]
synonym: "Xrn1" RELATED Gene-based [UniProtKB:P97789]
synonym: "mXRN1" EXACT PRO-short-label [PRO:DNx]
synonym: "protein Dhm2 (mouse)" EXACT [UniProtKB:P97789]
synonym: "strand-exchange protein 1 homolog (mouse)" EXACT [UniProtKB:P97789]
xref: UniProtKB:P97789
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000017511 ! 5'-3' exoribonuclease 1
relationship: has_gene_template MGI:891964 ! Xrn1 (mouse)

[Term]
id: PR:P22147
name: 5'-3' exoribonuclease 1 (yeast)
def: "A 5'-3' exoribonuclease 1 that is encoded in the genome of yeast." [OMA:P22147, PANTHER:PTHR12341:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "DST2" RELATED Gene-based [UniProtKB:P22147]
synonym: "KEM1" RELATED Gene-based [UniProtKB:P22147]
synonym: "RAR5" RELATED Gene-based [UniProtKB:P22147]
synonym: "SEP1" RELATED Gene-based [UniProtKB:P22147]
synonym: "SKI1" RELATED Gene-based [UniProtKB:P22147]
synonym: "XRN1" RELATED Gene-based [UniProtKB:P22147]
synonym: "G1645" RELATED Gene-based [UniProtKB:P22147]
synonym: "yXRN1" EXACT PRO-short-label [PRO:DNx]
synonym: "YGL173C" RELATED Gene-based [UniProtKB:P22147]
synonym: "p175 (yeast)" BROAD [UniProtKB:P22147]
synonym: "STP-beta (yeast)" EXACT [UniProtKB:P22147]
synonym: "strand exchange protein 1 (yeast)" EXACT [UniProtKB:P22147]
synonym: "DNA strand transfer protein beta (yeast)" EXACT [UniProtKB:P22147]
synonym: "KAR(-)-enhancing mutation protein (yeast)" EXACT [UniProtKB:P22147]
xref: UniProtKB:P22147
intersection_of: only_in_taxon NCBITaxon:559292 ! Saccharomyces cerevisiae S288C
intersection_of: PR:000017511 ! 5'-3' exoribonuclease 1
relationship: has_gene_template SGD:S000003141 ! XRN1 (yeast)

[Term]
id: PR:Q8IZH2-1
name: 5'-3' exoribonuclease 1 isoform h1 (human)
def: "A 5'-3' exoribonuclease 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IZH2-1." [PRO:DNx, UniProtKB:Q8IZH2]
comment: Category=organism-sequence.
synonym: "hXRN1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IZH2-1
is_a: PR:Q8IZH2 ! 5'-3' exoribonuclease 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8IZH2-2
name: 5'-3' exoribonuclease 1 isoform h2 (human)
def: "A 5'-3' exoribonuclease 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IZH2-2." [PRO:DNx, UniProtKB:Q8IZH2]
comment: Category=organism-sequence.
synonym: "hXRN1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IZH2-2
is_a: PR:Q8IZH2 ! 5'-3' exoribonuclease 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000017511
name: 5'-3' exoribonuclease 1
def: "A protein that is a translation product of the human XRN1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Exo" RELATED Gene-based []
synonym: "Dhm2" RELATED Gene-based []
synonym: "SEP1" RELATED Gene-based []
synonym: "XRN1" EXACT PRO-short-label [PRO:DNx]
synonym: "protein Dhm2" EXACT []
synonym: "strand-exchange protein 1 homolog" EXACT []
is_a: PR:000000001 ! protein