[Term] id: PR:P56695 name: wolframin (mouse) def: "A wolframin that is encoded in the genome of mouse." [OMA:P56695, PRO:DNx] comment: Category=organism-gene. synonym: "Wfs1" RELATED Gene-based [UniProtKB:P56695] synonym: "mWFS1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:P56695 intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000017414 ! wolframin relationship: has_gene_template MGI:1328355 ! Wfs1 (mouse) [Term] id: PR:O76024 name: wolframin (human) def: "A wolframin that is encoded in the genome of human." [PRO:DNx, UniProtKB:O76024] comment: Category=organism-gene. synonym: "WFS1" RELATED Gene-based [UniProtKB:O76024] synonym: "hWFS1" EXACT PRO-short-label [PRO:DNx] xref: Reactome:R-HSA-535474 "PR:O76024 located_in GO:0005789" xref: Reactome:R-HSA-8956747 "PR:O76024 located_in GO:0005788" xref: UniProtKB:O76024 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000017414 ! wolframin relationship: has_gene_template HGNC:12762 ! WFS1 (human) [Term] id: PR:Q8IMZ9-2 name: wolframin isoform C (fruit fly) def: "A wolframin (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IMZ9-2." [PRO:DNx, UniProtKB:Q8IMZ9] comment: Category=organism-sequence. synonym: "fly-WFS1/iso:C" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8IMZ9-2 is_a: PR:Q8IMZ9 ! wolframin (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:000030179 name: wolframin phosphorylated 1 (mouse) def: "A wolframin phosphorylated 1 in mouse. UniProtKB:P56695, Ser-32, MOD:00046." [PMID:17114649, PRO:HJD] comment: Category=organism-modification. Note: Large-scale experiment. synonym: "mWFS1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:P56695, Ser-32, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx] intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus intersection_of: PR:000030178 ! wolframin phosphorylated 1 relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:000030178 name: wolframin phosphorylated 1 def: "A wolframin that has been phosphorylated at the position equivalent to Ser-32 of the amino acid sequence represented by UniProtKB:P56695. Example: UniProtKB:P56695, Ser-32, MOD:00046." [PMID:17114649, PRO:HJD] comment: Category=modification. Note: Large-scale experiment. synonym: "WFS1/Phos:1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000017414 ! wolframin relationship: has_part MOD:00046 ! O-phospho-L-serine [Term] id: PR:000017414 name: wolframin def: "A protein that is a translation product of the human WFS1 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "WFS1" EXACT PRO-short-label [PRO:DNx] is_a: PR:000000001 ! protein [Term] id: PR:Q8IMZ9-1 name: wolframin isoform A (fruit fly) def: "A wolframin (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IMZ9-1." [PRO:DNx, UniProtKB:Q8IMZ9] comment: Category=organism-sequence. synonym: "fly-WFS1/iso:A" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8IMZ9-1 is_a: PR:Q8IMZ9 ! wolframin (fruit fly) relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster [Term] id: PR:Q8IMZ9 name: wolframin (fruit fly) def: "A wolframin that is encoded in the genome of fruit fly." [OMA:Q8IMZ9, PRO:DNx] comment: Category=organism-gene. synonym: "wfs1" RELATED Gene-based [UniProtKB:Q8IMZ9] synonym: "CG4917" RELATED Gene-based [UniProtKB:Q8IMZ9] synonym: "fly-WFS1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q8IMZ9 intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster intersection_of: PR:000017414 ! wolframin relationship: has_gene_template FlyBase:FBgn0039003 ! wfs1 (fruit fly)