[Term]
id: PR:000048134
name: histone-lysine N-methyltransferase 2B, initiator methionine removed form (human)
def: "A histone-lysine N-methyltransferase 2B (human) that has had the initiator methionine removed. UniProtKB:Q9UMN6, 2-2715." [PRO:DNx, Reactome:R-HSA-1183216]
comment: Category=organism-modification.
synonym: "PRO_0000124881" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hKMT2B/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9UMN6, 2-2715" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-1183216 "PR:000048134 located_in GO:0005654"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q9UMN6 ! histone-lysine N-methyltransferase 2B (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9UMN6-1
name: histone-lysine N-methyltransferase 2B isoform 1 (human)
def: "A histone-lysine N-methyltransferase 2B (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9UMN6-1." [PRO:DNx, UniProtKB:Q9UMN6]
comment: Category=organism-sequence.
synonym: "hKMT2B/iso:1" EXACT PRO-short-label [PRO:DNx]
synonym: "histone-lysine N-methyltransferase 2B isoform Long (human)" EXACT [UniProtKB:Q9UMN6]
xref: UniProtKB:Q9UMN6-1
is_a: PR:Q9UMN6 ! histone-lysine N-methyltransferase 2B (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9UMN6
name: histone-lysine N-methyltransferase 2B (human)
def: "A histone-lysine N-methyltransferase 2B that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-gene.
synonym: "HRX2" RELATED Gene-based [UniProtKB:Q9UMN6]
synonym: "MLL2" RELATED Gene-based [UniProtKB:Q9UMN6]
synonym: "MLL4" RELATED Gene-based [UniProtKB:Q9UMN6]
synonym: "TRX2" RELATED Gene-based [UniProtKB:Q9UMN6]
synonym: "WBP7" RELATED Gene-based [UniProtKB:Q9UMN6]
synonym: "KMT2B" RELATED Gene-based [UniProtKB:Q9UMN6]
synonym: "hKMT2B" EXACT PRO-short-label [PRO:DNx]
synonym: "KIAA0304" RELATED Gene-based [UniProtKB:Q9UMN6]
synonym: "WBP-7 (human)" EXACT [UniProtKB:Q9UMN6]
synonym: "trithorax homolog 2 (human)" EXACT [UniProtKB:Q9UMN6]
synonym: "WW domain-binding protein 7 (human)" EXACT [UniProtKB:Q9UMN6]
synonym: "lysine N-methyltransferase 2B (human)" EXACT [UniProtKB:Q9UMN6]
synonym: "myeloid/lymphoid or mixed-lineage leukemia protein 4 (human)" EXACT [UniProtKB:Q9UMN6]
xref: UniProtKB:Q9UMN6
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000017379 ! histone-lysine N-methyltransferase 2B
relationship: has_gene_template HGNC:15840 ! KMT2B (human)

[Term]
id: PR:000017379
name: histone-lysine N-methyltransferase 2B
def: "A protein that is a translation product of the human KMT2B gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "HRX2" RELATED Gene-based []
synonym: "MLL2" RELATED Gene-based []
synonym: "MLL4" RELATED Gene-based []
synonym: "TRX2" RELATED Gene-based []
synonym: "WBP7" RELATED Gene-based []
synonym: "KMT2B" EXACT PRO-short-label [PRO:DNx]
synonym: "KMT2D" BROAD [PRO:DNx]
synonym: "WBP-7" EXACT []
synonym: "KIAA0304" RELATED Gene-based []
synonym: "trithorax homolog 2" EXACT []
synonym: "WW domain-binding protein 7" EXACT []
synonym: "lysine N-methyltransferase 2B" BROAD []
synonym: "lysine N-methyltransferase 2D" BROAD [PRO:DNx]
synonym: "histone-lysine N-methyltransferase MLL4" EXACT []
synonym: "myeloid/lymphoid or mixed-lineage leukemia protein 4" EXACT []
synonym: "myeloid/lymphoid or mixed-lineage leukemia protein 4 homolog" EXACT []
xref: IUPHARobj:2689
is_a: PR:000000001 ! protein