[Term]
id: PR:000017369
name: tryptophan--tRNA ligase, cytoplasmic
def: "A protein that is a translation product of the human WARS1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "WRS" RELATED Gene-based []
synonym: "WARS" RELATED Gene-based []
synonym: "IFI53" RELATED Gene-based []
synonym: "IFP53" EXACT []
synonym: "TrpRS" BROAD [PRO:DAN]
synonym: "WARS1" EXACT PRO-short-label [PRO:DNx]
synonym: "tryptophan--tRNA ligase" BROAD [PRO:DAN]
synonym: "tryptophanyl-tRNA synthetase" BROAD [PRO:DAN]
synonym: "interferon-induced protein 53" EXACT []
synonym: "tryptophanyl-tRNA synthetase, cytoplasmic" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000049667
name: tryptophan--tRNA ligase, cytoplasmic, initiator methionine removed form (human)
def: "A tryptophan--tRNA ligase, cytoplasmic (human) that has had the initiator methionine removed. UniProtKB:P23381, 2-471." [PRO:DNx, Reactome:R-HSA-379603]
comment: Category=organism-modification.
synonym: "PRO_0000136738" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hWARS/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P23381, 2-471" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-379603 "PR:000049667 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P23381 ! tryptophan--tRNA ligase, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P23381-2
name: tryptophan--tRNA ligase, cytoplasmic isoform h2 (human)
def: "A tryptophan--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23381-2." [PRO:DNx, UniProtKB:P23381]
comment: Category=organism-sequence.
synonym: "hWARS1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "tryptophan--tRNA ligase, cytoplasmic isoform mini TrpRS (human)" EXACT [UniProtKB:P23381]
xref: UniProtKB:P23381-2
is_a: PR:P23381 ! tryptophan--tRNA ligase, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P23381
name: tryptophan--tRNA ligase, cytoplasmic (human)
def: "A tryptophan--tRNA ligase, cytoplasmic that is encoded in the genome of human." [PRO:DNx, UniProtKB:P23381]
comment: Category=organism-gene.
synonym: "WRS" RELATED Gene-based [UniProtKB:P23381]
synonym: "WARS" RELATED Gene-based [UniProtKB:P23381]
synonym: "hWRS" EXACT [UniProtKB:P23381]
synonym: "IFI53" RELATED Gene-based [UniProtKB:P23381]
synonym: "WARS1" RELATED Gene-based [UniProtKB:P23381]
synonym: "hWARS1" EXACT PRO-short-label [PRO:DNx]
synonym: "IFP53 (human)" EXACT [UniProtKB:P23381]
synonym: "TrpRS (human)" BROAD [PRO:DAN]
synonym: "tryptophan--tRNA ligase (human)" BROAD [PRO:DAN]
synonym: "tryptophanyl-tRNA synthetase (human)" BROAD [PRO:DAN]
synonym: "interferon-induced protein 53 (human)" EXACT [UniProtKB:P23381]
synonym: "tryptophanyl-tRNA synthetase, cytoplasmic (human)" EXACT [PRO:DAN]
xref: UniProtKB:P23381
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000017369 ! tryptophan--tRNA ligase, cytoplasmic
relationship: has_gene_template HGNC:12729 ! WARS1 (human)

[Term]
id: PR:P23381-1
name: tryptophan--tRNA ligase, cytoplasmic isoform h1 (human)
def: "A tryptophan--tRNA ligase, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P23381-1." [PRO:DNx, UniProtKB:P23381]
comment: Category=organism-sequence.
synonym: "hWARS1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P23381-1
is_a: PR:P23381 ! tryptophan--tRNA ligase, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens