[Term]
id: PR:P63044-1
name: vesicle-associated membrane protein 2 isoform 1 (mouse)
def: "A vesicle-associated membrane protein 2 isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mVAMP2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P63044-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000040064 ! vesicle-associated membrane protein 2 isoform 1

[Term]
id: PR:P63027-1
name: vesicle-associated membrane protein 2 isoform 1 (human)
def: "A vesicle-associated membrane protein 2 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hVAMP2/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P63027-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000040064 ! vesicle-associated membrane protein 2 isoform 1

[Term]
id: PR:P18489
name: synaptobrevin (fruit fly)
def: "A vesicle-associated membrane protein 2 that is encoded in the genome of fruit fly." [PRO:DNx]
comment: Category=organism-gene.
synonym: "Syb" RELATED Gene-based [UniProtKB:P18489]
synonym: "CG12210" RELATED Gene-based [UniProtKB:P18489]
synonym: "fly-VAMP2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P18489
intersection_of: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster
intersection_of: PR:000017249 ! vesicle-associated membrane protein 2
relationship: has_gene_template FlyBase:FBgn0003660 ! Syb (fruit fly)

[Term]
id: PR:P63027
name: vesicle-associated membrane protein 2 (human)
def: "A vesicle-associated membrane protein 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:P63027]
comment: Category=organism-gene.
synonym: "SYB2" RELATED Gene-based [UniProtKB:P63027]
synonym: "VAMP2" RELATED Gene-based [UniProtKB:P63027]
synonym: "hVAMP2" EXACT PRO-short-label [PRO:DNx]
synonym: "VAMP-2 (human)" EXACT [UniProtKB:P63027]
synonym: "synaptobrevin-2 (human)" EXACT [UniProtKB:P63027]
xref: UniProtKB:P63027
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000017249 ! vesicle-associated membrane protein 2
relationship: has_gene_template HGNC:12643 ! VAMP2 (human)

[Term]
id: PR:P63044
name: vesicle-associated membrane protein 2 (mouse)
def: "A vesicle-associated membrane protein 2 that is encoded in the genome of mouse." [PRO:DNx, UniProtKB:P63044]
comment: Category=organism-gene.
synonym: "Syb2" RELATED Gene-based [UniProtKB:P63044]
synonym: "Vamp2" RELATED Gene-based [UniProtKB:P63044]
synonym: "mVAMP2" EXACT PRO-short-label [PRO:DNx]
synonym: "VAMP-2 (mouse)" EXACT [UniProtKB:P63044]
synonym: "synaptobrevin-2 (mouse)" EXACT [UniProtKB:P63044]
xref: UniProtKB:P63044
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000017249 ! vesicle-associated membrane protein 2
relationship: has_gene_template MGI:1313277 ! Vamp2 (mouse)

[Term]
id: PR:P18489-3
name: synaptobrevin isoform A (fruit fly)
def: "A synaptobrevin (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18489-3." [PRO:DNx, UniProtKB:P18489]
comment: Category=organism-sequence.
synonym: "fly-VAMP2/iso:A" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P18489-3
is_a: PR:P18489 ! synaptobrevin (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:000049635
name: vesicle-associated membrane protein 2, initiator methionine removed form (human)
def: "A vesicle-associated membrane protein 2 (human) that has had the initiator methionine removed. UniProtKB:P63027, 2-116." [PRO:DNx, Reactome:R-HSA-181517, Reactome:R-HSA-210516, Reactome:R-HSA-375425, Reactome:R-HSA-379363, Reactome:R-HSA-432703, Reactome:R-HSA-8869129, Reactome:R-HSA-917738]
comment: Category=organism-modification.
synonym: "PRO_0000206723" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hVAMP2/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P63027, 2-116" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-181517 "PR:000049635 located_in GO:0030672"
xref: Reactome:R-HSA-210365 "PR:000049635 located_in GO:0060203"
xref: Reactome:R-HSA-210516 "PR:000049635 located_in GO:0005886"
xref: Reactome:R-HSA-265198 "PR:000049635 located_in GO:0030667"
xref: Reactome:R-HSA-372517 "PR:000049635 located_in GO:0060203"
xref: Reactome:R-HSA-375425 "PR:000049635 located_in GO:0000139"
xref: Reactome:R-HSA-375436 "PR:000049635 located_in GO:0030659"
xref: Reactome:R-HSA-376363 "PR:000049635 located_in GO:0030667"
xref: Reactome:R-HSA-379363 "PR:000049635 located_in GO:0070083"
xref: Reactome:R-HSA-917738 "PR:000049635 located_in GO:0061202"
xref: Reactome:R-HSA-432703 "PR:000049635 located_in GO:0005765"
xref: Reactome:R-HSA-1449630 "PR:000049635 located_in GO:0030659"
xref: Reactome:R-HSA-9609882 "PR:000049635 located_in GO:0005829"
xref: Reactome:R-HSA-9609886 "PR:000049635 located_in GO:0005789"
xref: Reactome:R-HSA-8869129 "PR:000049635 located_in GO:0030665"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P63027 ! vesicle-associated membrane protein 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P18489-2
name: synaptobrevin isoform Syb-B (fruit fly)
def: "A synaptobrevin (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18489-2." [PRO:DNx, UniProtKB:P18489]
comment: Category=organism-sequence.
synonym: "fly-VAMP2/iso:Syb-B" EXACT PRO-short-label [PRO:DNx]
synonym: "synaptobrevin isoform B (fruit fly)" EXACT [UniProtKB:P18489]
xref: UniProtKB:P18489-2
is_a: PR:P18489 ! synaptobrevin (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:P18489-4
name: synaptobrevin isoform D (fruit fly)
def: "A synaptobrevin (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18489-4." [PRO:DNx, UniProtKB:P18489]
comment: Category=organism-sequence.
synonym: "fly-VAMP2/iso:D" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P18489-4
is_a: PR:P18489 ! synaptobrevin (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:000040064
name: vesicle-associated membrane protein 2 isoform 1
def: "A vesicle-associated membrane protein 2 that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P63027-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "VAMP2/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000017249 ! vesicle-associated membrane protein 2

[Term]
id: PR:000017249
name: vesicle-associated membrane protein 2
def: "A protein that is a translation product of the human VAMP2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "SYB2" RELATED Gene-based []
synonym: "VAMP2" EXACT PRO-short-label [PRO:DNx]
synonym: "VAMP-2" EXACT []
synonym: "synaptobrevin-2" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:P18489-1
name: synaptobrevin isoform Syb-A (fruit fly)
def: "A synaptobrevin (fruit fly) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P18489-1." [PRO:DNx, UniProtKB:P18489]
comment: Category=organism-sequence.
synonym: "fly-VAMP2/iso:Syb-A" EXACT PRO-short-label [PRO:DNx]
synonym: "synaptobrevin isoform C (fruit fly)" EXACT [UniProtKB:P18489]
xref: UniProtKB:P18489-1
is_a: PR:P18489 ! synaptobrevin (fruit fly)
relationship: only_in_taxon NCBITaxon:7227 ! Drosophila melanogaster

[Term]
id: PR:000030175
name: vesicle-associated membrane protein 2 phosphorylated 1 (mouse)
def: "A vesicle-associated membrane protein 2 phosphorylated 1 in mouse. UniProtKB:P63044, Ser-75, MOD:00046." [PMID:17114649, PRO:HJD]
comment: Category=organism-modification. Note: Large-scale experiment.
synonym: "mVAMP2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P63044, Ser-75, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000030174 ! vesicle-associated membrane protein 2 phosphorylated 1
relationship: has_part MOD:00046 ! O-phospho-L-serine

[Term]
id: PR:000030174
name: vesicle-associated membrane protein 2 phosphorylated 1
def: "A vesicle-associated membrane protein 2 that has been phosphorylated at the position equivalent to Ser-75 of the amino acid sequence represented by UniProtKB:P63044. Example: UniProtKB:P63044, Ser-75, MOD:00046." [PMID:17114649, PRO:HJD]
comment: Category=modification. Note: Large-scale experiment.
synonym: "VAMP2/Phos:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000017249 ! vesicle-associated membrane protein 2
relationship: has_part MOD:00046 ! O-phospho-L-serine