[Term]
id: PR:Q8TBC4-1
name: NEDD8-activating enzyme E1 catalytic subunit isoform h1 (human)
def: "A NEDD8-activating enzyme E1 catalytic subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TBC4-1." [PRO:DNx, UniProtKB:Q8TBC4]
comment: Category=organism-sequence.
synonym: "hUBA3/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8TBC4-1
is_a: PR:Q8TBC4 ! NEDD8-activating enzyme E1 catalytic subunit (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8TBC4-2
name: NEDD8-activating enzyme E1 catalytic subunit isoform h2 (human)
def: "A NEDD8-activating enzyme E1 catalytic subunit (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8TBC4-2." [PRO:DNx, UniProtKB:Q8TBC4]
comment: Category=organism-sequence.
synonym: "hUBA3/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8TBC4-2
is_a: PR:Q8TBC4 ! NEDD8-activating enzyme E1 catalytic subunit (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8TBC4
name: NEDD8-activating enzyme E1 catalytic subunit (human)
def: "A NEDD8-activating enzyme E1 catalytic subunit that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8TBC4]
comment: Category=organism-gene.
synonym: "UBA3" RELATED Gene-based [UniProtKB:Q8TBC4]
synonym: "UBE1C" RELATED Gene-based [UniProtKB:Q8TBC4]
synonym: "hUBA3" EXACT PRO-short-label [PRO:DNx]
synonym: "NEDD8-activating enzyme E1C (human)" EXACT [UniProtKB:Q8TBC4]
synonym: "ubiquitin-activating enzyme 3 (human)" EXACT [UniProtKB:Q8TBC4]
synonym: "ubiquitin-activating enzyme E1C (human)" EXACT [UniProtKB:Q8TBC4]
synonym: "ubiquitin-like modifier-activating enzyme 3 (human)" EXACT [UniProtKB:Q8TBC4]
xref: UniProtKB:Q8TBC4
xref: Reactome:R-HSA-947632 "PR:Q8TBC4 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016952 ! NEDD8-activating enzyme E1 catalytic subunit
relationship: has_gene_template HGNC:12470 ! UBA3 (human)

[Term]
id: PR:000016952
name: NEDD8-activating enzyme E1 catalytic subunit
def: "A protein that is a translation product of the human UBA3 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "UBA3" EXACT PRO-short-label [PRO:DNx]
synonym: "UBE1C" RELATED Gene-based []
synonym: "NEDD8-activating enzyme E1C" EXACT []
synonym: "ubiquitin-activating enzyme 3" EXACT []
synonym: "ubiquitin-activating enzyme E1C" EXACT []
synonym: "ubiquitin-like modifier-activating enzyme 3" EXACT []
is_a: PR:000000001 ! protein