[Term]
id: PR:Q9JMH6-2
name: thioredoxin reductase 1, cytoplasmic isoform m2 (mouse)
def: "A thioredoxin reductase 1, cytoplasmic (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JMH6-2." [PRO:DNx, UniProtKB:Q9JMH6]
comment: Category=organism-sequence.
synonym: "mTXNRD1/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9JMH6-2
is_a: PR:Q9JMH6 ! thioredoxin reductase 1, cytoplasmic (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q9JMH6-1
name: thioredoxin reductase 1, cytoplasmic isoform m1 (mouse)
def: "A thioredoxin reductase 1, cytoplasmic (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9JMH6-1." [PRO:DNx, UniProtKB:Q9JMH6]
comment: Category=organism-sequence.
synonym: "mTXNRD1/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9JMH6-1
is_a: PR:Q9JMH6 ! thioredoxin reductase 1, cytoplasmic (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q16881-5
name: thioredoxin reductase 1, cytoplasmic isoform h5 (human)
def: "A thioredoxin reductase 1, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16881-5." [PRO:DNx, UniProtKB:Q16881]
comment: Category=organism-sequence.
synonym: "hTXNRD1/iso:h5" EXACT PRO-short-label [PRO:DNx]
synonym: "thioredoxin reductase 1, cytoplasmic isoform I (human)" EXACT [UniProtKB:Q16881]
synonym: "thioredoxin reductase 1, cytoplasmic isoform TrxR1a (human)" EXACT [UniProtKB:Q16881]
synonym: "thioredoxin reductase 1, cytoplasmic isoform TXNRD1_v1 (human)" EXACT [UniProtKB:Q16881]
xref: UniProtKB:Q16881-5
is_a: PR:Q16881 ! thioredoxin reductase 1, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16881-4
name: thioredoxin reductase 1, cytoplasmic isoform h4 (human)
def: "A thioredoxin reductase 1, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16881-4." [PRO:DNx, UniProtKB:Q16881]
comment: Category=organism-sequence.
synonym: "hTXNRD1/iso:h4" EXACT PRO-short-label [PRO:DNx]
synonym: "thioredoxin reductase 1, cytoplasmic isoform IV (human)" EXACT [UniProtKB:Q16881]
synonym: "thioredoxin reductase 1, cytoplasmic isoform TrxR1b (human)" EXACT [UniProtKB:Q16881]
synonym: "thioredoxin reductase 1, cytoplasmic isoform TXNRD1_v2 (human)" EXACT [UniProtKB:Q16881]
xref: UniProtKB:Q16881-4
is_a: PR:Q16881 ! thioredoxin reductase 1, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16881-7
name: thioredoxin reductase 1, cytoplasmic isoform h7 (human)
def: "A thioredoxin reductase 1, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16881-7." [PRO:DNx, UniProtKB:Q16881]
comment: Category=organism-sequence.
synonym: "hTXNRD1/iso:h7" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q16881-7
is_a: PR:Q16881 ! thioredoxin reductase 1, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16881-6
name: thioredoxin reductase 1, cytoplasmic isoform h6 (human)
def: "A thioredoxin reductase 1, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16881-6." [PRO:DNx, UniProtKB:Q16881]
comment: Category=organism-sequence.
synonym: "hTXNRD1/iso:h6" EXACT PRO-short-label [PRO:DNx]
synonym: "thioredoxin reductase 1, cytoplasmic isoform VI (human)" EXACT [UniProtKB:Q16881]
xref: UniProtKB:Q16881-6
is_a: PR:Q16881 ! thioredoxin reductase 1, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16881-1
name: thioredoxin reductase 1, cytoplasmic isoform h1 (human)
def: "A thioredoxin reductase 1, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16881-1." [PRO:DNx, UniProtKB:Q16881]
comment: Category=organism-sequence.
synonym: "hTXNRD1/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "thioredoxin reductase 1, cytoplasmic isoform V (human)" EXACT [UniProtKB:Q16881]
synonym: "thioredoxin reductase 1, cytoplasmic isoform TXNRD1_v3 (human)" EXACT [UniProtKB:Q16881]
xref: UniProtKB:Q16881-1
is_a: PR:Q16881 ! thioredoxin reductase 1, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16881-3
name: thioredoxin reductase 1, cytoplasmic isoform h3 (human)
def: "A thioredoxin reductase 1, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16881-3." [PRO:DNx, UniProtKB:Q16881]
comment: Category=organism-sequence.
synonym: "hTXNRD1/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "thioredoxin reductase 1, cytoplasmic isoform III (human)" EXACT [UniProtKB:Q16881]
synonym: "thioredoxin reductase 1, cytoplasmic isoform TXNRD1_v5 (human)" EXACT [UniProtKB:Q16881]
xref: UniProtKB:Q16881-3
is_a: PR:Q16881 ! thioredoxin reductase 1, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q16881-2
name: thioredoxin reductase 1, cytoplasmic isoform h2 (human)
def: "A thioredoxin reductase 1, cytoplasmic (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q16881-2." [PRO:DNx, UniProtKB:Q16881]
comment: Category=organism-sequence.
synonym: "hTXNRD1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "thioredoxin reductase 1, cytoplasmic isoform II (human)" EXACT [UniProtKB:Q16881]
synonym: "thioredoxin reductase 1, cytoplasmic isoform TXNRD1_v4 (human)" EXACT [UniProtKB:Q16881]
xref: UniProtKB:Q16881-2
is_a: PR:Q16881 ! thioredoxin reductase 1, cytoplasmic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O89049
name: thioredoxin reductase 1, cytoplasmic (rat)
def: "A thioredoxin reductase 1, cytoplasmic that is encoded in the genome of rat." [OMA:O89049, PRO:DNx]
comment: Category=organism-gene. Requested by=PubChem.
synonym: "Trxr1" RELATED Gene-based [UniProtKB:O89049]
synonym: "Txnrd1" RELATED Gene-based [UniProtKB:O89049]
synonym: "rTXNRD1" EXACT PRO-short-label [PRO:DNx]
synonym: "TR (rat)" EXACT [UniProtKB:O89049]
synonym: "peroxidase TXNRD1 (rat)" EXACT [UniProtKB:O89049]
synonym: "thioredoxin reductase TR1 (rat)" EXACT [UniProtKB:O89049]
synonym: "NADPH-dependent thioredoxin reductase (rat)" EXACT [UniProtKB:O89049]
xref: UniProtKB:O89049
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000016871 ! thioredoxin reductase 1, cytoplasmic
relationship: has_gene_template RGD:61959 ! Txnrd1 (rat)

[Term]
id: PR:000016871
name: thioredoxin reductase 1, cytoplasmic
def: "A protein that is a translation product of the human TXNRD1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TR" RELATED []
synonym: "KDRF" RELATED Gene-based []
synonym: "Trxr1" RELATED Gene-based []
synonym: "GRIM12" RELATED Gene-based []
synonym: "TXNRD1" EXACT PRO-short-label [PRO:DNx]
synonym: "GRIM-12" EXACT []
synonym: "peroxidase TXNRD1" EXACT []
synonym: "thioredoxin reductase TR1" EXACT []
synonym: "KM-102-derived reductase-like factor" EXACT []
synonym: "gene associated with retinoic and IFN-induced mortality 12 protein" EXACT []
synonym: "gene associated with retinoic and interferon-induced mortality 12 protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000021759
name: thioredoxin reductase 1, cytoplasmic proteolytic cleavage product
def: "A thioredoxin reductase 1, cytoplasmic that has been processed by proteolytic cleavage." [PRO:DNx]
comment: Category=modification.
synonym: "TXNRD1/ClvPrd" EXACT PRO-short-label [PRO:DNx]
intersection_of: output_of GO:0016485 ! protein processing
intersection_of: PR:000016871 ! thioredoxin reductase 1, cytoplasmic

[Term]
id: PR:Q9JMH6
name: thioredoxin reductase 1, cytoplasmic (mouse)
def: "A thioredoxin reductase 1, cytoplasmic that is encoded in the genome of mouse." [OMA:Q9JMH6, PRO:DAN]
comment: Category=organism-gene.
synonym: "Trxr1" RELATED Gene-based [UniProtKB:Q9JMH6]
synonym: "Txnrd1" RELATED Gene-based [UniProtKB:Q9JMH6]
synonym: "mTXNRD1" EXACT PRO-short-label [PRO:DNx]
synonym: "TR (mouse)" EXACT [UniProtKB:Q9JMH6]
synonym: "peroxidase TXNRD1 (mouse)" EXACT [UniProtKB:Q9JMH6]
synonym: "thioredoxin reductase TR1 (mouse)" EXACT [UniProtKB:Q9JMH6]
xref: UniProtKB:Q9JMH6
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000016871 ! thioredoxin reductase 1, cytoplasmic
relationship: has_gene_template MGI:1354175 ! Txnrd1 (mouse)

[Term]
id: PR:Q16881
name: thioredoxin reductase 1, cytoplasmic (human)
def: "A thioredoxin reductase 1, cytoplasmic that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q16881]
comment: Category=organism-gene.
synonym: "KDRF" RELATED Gene-based [UniProtKB:Q16881]
synonym: "GRIM12" RELATED Gene-based [UniProtKB:Q16881]
synonym: "TXNRD1" RELATED Gene-based [UniProtKB:Q16881]
synonym: "hTXNRD1" EXACT PRO-short-label [PRO:DNx]
synonym: "TR (human)" BROAD [UniProtKB:Q16881]
synonym: "GRIM-12 (human)" EXACT [UniProtKB:Q16881]
synonym: "peroxidase TXNRD1 (human)" EXACT [UniProtKB:Q16881]
synonym: "thioredoxin reductase TR1 (human)" EXACT [UniProtKB:Q16881]
synonym: "KM-102-derived reductase-like factor (human)" EXACT [UniProtKB:Q16881]
synonym: "gene associated with retinoic and IFN-induced mortality 12 protein (human)" EXACT [UniProtKB:Q16881]
synonym: "gene associated with retinoic and interferon-induced mortality 12 protein (human)" EXACT [UniProtKB:Q16881]
xref: UniProtKB:Q16881
xref: Reactome:R-HSA-73531 "PR:Q16881 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016871 ! thioredoxin reductase 1, cytoplasmic
relationship: has_gene_template HGNC:12437 ! TXNRD1 (human)