[Term]
id: PR:000016801
name: transthyretin
def: "A protein that is a translation product of the human TTR gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TTR" EXACT PRO-short-label [PRO:DNx]
synonym: "ATTR" EXACT []
synonym: "PALB" RELATED Gene-based []
synonym: "TBPA" BROAD [PRO:DNx]
synonym: "prealbumin" EXACT []
xref: IUPHARobj:2851
is_a: PR:000000001 ! protein

[Term]
id: PR:P27731
name: transthyretin (chicken)
def: "A transthyretin that is encoded in the genome of chicken." [OMA:P27731, PANTHER:PTHR10395:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "TTR" RELATED Gene-based [UniProtKB:P27731]
synonym: "chick-TTR" EXACT PRO-short-label [PRO:DNx]
synonym: "TBPA (chicken)" EXACT [UniProtKB:P27731]
synonym: "prealbumin (chicken)" EXACT [UniProtKB:P27731]
xref: UniProtKB:P27731
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000016801 ! transthyretin
relationship: has_gene_template NCBIGene:396277 ! TTR (chicken)

[Term]
id: PR:P07309
name: transthyretin (mouse)
def: "A transthyretin that is encoded in the genome of mouse." [OMA:P07309, PRO:DNx]
comment: Category=organism-gene.
synonym: "Ttr" RELATED Gene-based [UniProtKB:P07309]
synonym: "mTTR" EXACT PRO-short-label [PRO:DNx]
synonym: "prealbumin (mouse)" EXACT [UniProtKB:P07309]
xref: UniProtKB:P07309
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000016801 ! transthyretin
relationship: has_gene_template MGI:98865 ! Ttr (mouse)

[Term]
id: PR:P02767-1
name: transthyretin isoform 1 (rat)
def: "A transthyretin isoform 1 that is encoded in the genome of rat." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "rTTR/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P02767-1
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000038639 ! transthyretin isoform 1

[Term]
id: PR:000021745
name: transthyretin, signal peptide removed form
def: "A transthyretin that has had the signal peptide removed." [PRO:DNx]
comment: Category=modification.
synonym: "TTR/SigPep-" EXACT PRO-short-label [PRO:DNx]
intersection_of: PR:000016801 ! transthyretin
intersection_of: lacks_part SO:0000418 ! signal_peptide

[Term]
id: PR:P02766-1
name: transthyretin isoform 1 (human)
def: "A transthyretin isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hTTR/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P02766-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038639 ! transthyretin isoform 1

[Term]
id: PR:000038639
name: transthyretin isoform 1
def: "A transthyretin that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P02766-1 or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=sequence.
synonym: "TTR/iso:1" EXACT PRO-short-label [PRO:DNx]
is_a: PR:000016801 ! transthyretin

[Term]
id: PR:P07309-1
name: transthyretin isoform 1 (mouse)
def: "A transthyretin isoform 1 that is encoded in the genome of mouse." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "mTTR/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P07309-1
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000038639 ! transthyretin isoform 1

[Term]
id: PR:P02766
name: transthyretin (human)
def: "A transthyretin that is encoded in the genome of human." [PRO:DNx, UniProtKB:P02766]
comment: Category=organism-gene.
synonym: "TTR" RELATED Gene-based [UniProtKB:P02766]
synonym: "PALB" RELATED Gene-based [UniProtKB:P02766]
synonym: "hTTR" EXACT PRO-short-label [PRO:DNx]
synonym: "ATTR (human)" EXACT [UniProtKB:P02766]
synonym: "TBPA (human)" EXACT [UniProtKB:P02766]
synonym: "prealbumin (human)" EXACT [UniProtKB:P02766]
xref: UniProtKB:P02766
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016801 ! transthyretin
relationship: has_gene_template HGNC:12405 ! TTR (human)

[Term]
id: PR:000049562
name: transthyretin, signal peptide removed form (human)
def: "A transthyretin (human) that has had the signal peptide removed. UniProtKB:P02766, 21-147." [PRO:DNx, Reactome:R-HSA-976883]
comment: Category=organism-modification.
synonym: "hTTR/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000035755" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P02766, 21-147" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-976883 "PR:000049562 located_in GO:0005576"
xref: Reactome:R-HSA-6799366 "PR:000049562 located_in GO:0035578"
xref: TDR:18653
intersection_of: PR:P02766 ! transthyretin (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P02767
name: transthyretin (rat)
def: "A transthyretin that is encoded in the genome of rat." [OMA:P02767, PANTHER:PTHR10395:SF7, PRO:DNx]
comment: Category=organism-gene.
synonym: "Tt" RELATED Gene-based [UniProtKB:P02767]
synonym: "Ttr" RELATED Gene-based [UniProtKB:P02767]
synonym: "rTTR" EXACT PRO-short-label [PRO:DNx]
synonym: "TBPA (rat)" EXACT [UniProtKB:P02767]
synonym: "prealbumin (rat)" EXACT [UniProtKB:P02767]
xref: UniProtKB:P02767
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000016801 ! transthyretin
relationship: has_gene_template RGD:3916 ! Ttr (rat)