[Term]
id: PR:P35761
name: dual specificity protein kinase TTK (mouse)
def: "A dual specificity protein kinase TTK that is encoded in the genome of mouse." [OMA:MOUSE23899, PRO:DNx]
comment: Category=organism-gene.
synonym: "Esk" RELATED Gene-based [UniProtKB:P35761]
synonym: "Ttk" RELATED Gene-based [UniProtKB:P35761]
synonym: "mTTK" EXACT PRO-short-label [PRO:DNx]
synonym: "ESK (mouse)" EXACT [UniProtKB:P35761]
synonym: "PYT (mouse)" EXACT [UniProtKB:P35761]
xref: UniProtKB:P35761
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000016787 ! dual specificity protein kinase TTK
relationship: has_gene_template MGI:1194921 ! Ttk (mouse)

[Term]
id: PR:000049886
name: dual specificity protein kinase TTK isoform m2 phosphorylated 2 (mouse)
def: "A dual specificity protein kinase TTK isoform m2 (mouse) that has been phosphorylated at the position equivalent to Ser-794 of the amino acid sequence represented by UniProtKB:P35761-2. UniProtKB:P35761-2, Ser-794, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079).
synonym: "mTTK/iso:m2/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35761-2, Ser-794, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P35761-2 ! dual specificity protein kinase TTK isoform m2 (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049885
name: dual specificity protein kinase TTK isoform m2 phosphorylated 1 (mouse)
def: "A dual specificity protein kinase TTK isoform m2 (mouse) that has been phosphorylated at the position equivalent to Thr-402 of the amino acid sequence represented by UniProtKB:P35761-2. UniProtKB:P35761-2, Thr-402, MOD:00047." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079).
synonym: "mTTK/iso:m2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35761-2, Thr-402, MOD:00047" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P35761-2 ! dual specificity protein kinase TTK isoform m2 (mouse)
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000049884
name: dual specificity protein kinase TTK phosphorylated 1 (mouse)
def: "A dual specificity protein kinase TTK (mouse) that has been phosphorylated at positions equivalent to Thr-284 and Ser-287 of the amino acid sequence represented by UniProtKB:P35761-1. Example: UniProtKB:P35761-1, Thr-284, MOD:00047|Ser-287, MOD:00046." [PMID:21183079, PRO:HJD]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:21183079).
synonym: "mTTK/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P35761-1, Thr-284, MOD:00047|Ser-287, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P35761 ! dual specificity protein kinase TTK (mouse)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: has_part MOD:00047 ! O-phospho-L-threonine
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P35761-1
name: dual specificity protein kinase TTK isoform m1 (mouse)
def: "A dual specificity protein kinase TTK (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35761-1." [PRO:DNx, UniProtKB:P35761]
comment: Category=organism-sequence.
synonym: "mTTK/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35761-1
is_a: PR:P35761 ! dual specificity protein kinase TTK (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:P35761-2
name: dual specificity protein kinase TTK isoform m2 (mouse)
def: "A dual specificity protein kinase TTK (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P35761-2." [PRO:DNx, UniProtKB:P35761]
comment: Category=organism-sequence.
synonym: "mTTK/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P35761-2
is_a: PR:P35761 ! dual specificity protein kinase TTK (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000016787
name: dual specificity protein kinase TTK
def: "A protein that is a translation product of the human TTK gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ESK" EXACT []
synonym: "PYT" EXACT []
synonym: "TTK" EXACT PRO-short-label [PRO:DNx]
synonym: "MPS1" RELATED Gene-based []
synonym: "RPK1" RELATED []
synonym: "MPS1L1" RELATED Gene-based []
synonym: "Monopolar spindle protein 1" EXACT []
synonym: "serine/threonine-protein kinase MPS1" RELATED []
synonym: "Regulatory cell proliferation kinase 1" EXACT []
synonym: "phosphotyrosine picked threonine-protein kinase" EXACT []
xref: IUPHARobj:2264
is_a: PR:000000001 ! protein