[Term]
id: PR:O14773
name: tripeptidyl-peptidase 1 (human)
def: "A tripeptidyl-peptidase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:O14773]
comment: Category=organism-gene.
synonym: "CLN2" RELATED Gene-based [UniProtKB:O14773]
synonym: "GIG1" RELATED Gene-based [UniProtKB:O14773]
synonym: "TPP1" RELATED Gene-based [UniProtKB:O14773]
synonym: "hTPP1" EXACT PRO-short-label [PRO:DNx]
synonym: "LPIC (human)" EXACT [UniProtKB:O14773]
synonym: "TPP-1 (human)" EXACT [UniProtKB:O14773]
synonym: "TPP-I (human)" EXACT [UniProtKB:O14773]
synonym: "UNQ267/PRO304" RELATED Gene-based [UniProtKB:O14773]
synonym: "tripeptidyl-peptidase I (human)" EXACT [UniProtKB:O14773]
synonym: "tripeptidyl aminopeptidase (human)" BROAD [UniProtKB:O14773]
synonym: "cell growth-inhibiting gene 1 protein (human)" EXACT [UniProtKB:O14773]
synonym: "lysosomal pepstatin-insensitive protease (human)" EXACT [UniProtKB:O14773]
xref: UniProtKB:O14773
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016585 ! tripeptidyl-peptidase 1
relationship: has_gene_template HGNC:2073 ! TPP1 (human)

[Term]
id: PR:O14773-1
name: tripeptidyl-peptidase 1 isoform 1 (human)
def: "A tripeptidyl-peptidase 1 isoform 1 that is encoded in the genome of human." [PRO:DNx]
comment: Category=organism-sequence.
synonym: "hTPP1/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14773-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000037999 ! tripeptidyl-peptidase 1 isoform 1

[Term]
id: PR:O14773-2
name: tripeptidyl-peptidase 1 isoform h2 (human)
def: "A tripeptidyl-peptidase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O14773-2." [PRO:DNx, UniProtKB:O14773]
comment: Category=organism-sequence.
synonym: "hTPP1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O14773-2
is_a: PR:O14773 ! tripeptidyl-peptidase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000050704
name: tripeptidyl-peptidase 1 N-glycosylated 1 (human)
def: "A tripeptidyl-peptidase 1 (human) that has been N-glycosylated at the residue equivalent to Asn-210 of the amino acid sequence represented by UniProtKB:O14773-1, in which the glycan composition is represented by GlyTouCan:G80735OA. Example: UniProtKB:O14773-1, Asn-210, MOD:00160~GNO:G80735OA." [GlyGen:O14773-1, PMID:29671580, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTPP1/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O14773-1, Asn-210, MOD:00160~GNO:G80735OA" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O14773 ! tripeptidyl-peptidase 1 (human)
relationship: has_part GNO:G80735OA ! G80735OA
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000016585
name: tripeptidyl-peptidase 1
def: "A protein that is a translation product of the human TPP1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "CLN2" RELATED Gene-based []
synonym: "GIG1" RELATED Gene-based []
synonym: "LPIC" EXACT []
synonym: "TPP1" EXACT PRO-short-label [PRO:DNx]
synonym: "TPP-1" EXACT []
synonym: "TPP-I" EXACT []
synonym: "UNQ267/PRO304" RELATED Gene-based []
synonym: "tripeptidyl-peptidase I" EXACT []
synonym: "tripeptidyl aminopeptidase" BROAD [PRO:DNx]
synonym: "cell growth-inhibiting gene 1 protein" EXACT []
synonym: "lysosomal pepstatin-insensitive protease" EXACT []
is_a: PR:000000001 ! protein