[Term]
id: PR:Q8IWU9-1
name: tryptophan 5-hydroxylase 2 isoform a (human)
def: "A tryptophan 5-hydroxylase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IWU9-1." [PRO:DNx, UniProtKB:Q8IWU9]
comment: Category=organism-sequence.
synonym: "hTPH2/iso:a" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IWU9-1
is_a: PR:Q8IWU9 ! tryptophan 5-hydroxylase 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045988
name: tryptophan 5-hydroxylase 2 phosphorylated 1 (human)
def: "A tryptophan 5-hydroxylase 2 (human) that has been phosphorylated at the position equivalent to Ser-19 of the amino acid sequence represented by UniProtKB:Q8IWU9-1. Example: UniProtKB:Q8IWU9-1, Ser-19, MOD:00046." [PMID:15663479, iPTMnet:Q8IWU9]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:15663479). Status=unreviewed.
synonym: "hTPH2/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q8IWU9-1, Ser-19, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q8IWU9 ! tryptophan 5-hydroxylase 2 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q8IWU9
name: tryptophan 5-hydroxylase 2 (human)
def: "A tryptophan 5-hydroxylase 2 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q8IWU9]
comment: Category=organism-gene.
synonym: "NTPH" RELATED Gene-based [UniProtKB:Q8IWU9]
synonym: "TPH2" RELATED Gene-based [UniProtKB:Q8IWU9]
synonym: "hTPH2" EXACT PRO-short-label [PRO:DNx]
synonym: "tryptophan 5-monooxygenase 2 (human)" EXACT [UniProtKB:Q8IWU9]
synonym: "neuronal tryptophan hydroxylase (human)" EXACT [UniProtKB:Q8IWU9]
xref: UniProtKB:Q8IWU9
xref: Reactome:R-HSA-976257 "PR:Q8IWU9 located_in GO:0005829"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016576 ! tryptophan 5-hydroxylase 2
relationship: has_gene_template HGNC:20692 ! TPH2 (human)

[Term]
id: PR:000016576
name: tryptophan 5-hydroxylase 2
def: "A protein that is a translation product of the human TPH2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "NTPH" RELATED Gene-based []
synonym: "TPH2" EXACT PRO-short-label [PRO:DNx]
synonym: "tryptophan 5-monooxygenase 2" EXACT []
synonym: "neuronal tryptophan hydroxylase" EXACT []
xref: IUPHARobj:1242
is_a: PR:000000001 ! protein

[Term]
id: PR:Q8IWU9-2
name: tryptophan 5-hydroxylase 2 isoform b (human)
def: "A tryptophan 5-hydroxylase 2 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q8IWU9-2." [PRO:DNx, UniProtKB:Q8IWU9]
comment: Category=organism-sequence.
synonym: "hTPH2/iso:b" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q8IWU9-2
is_a: PR:Q8IWU9 ! tryptophan 5-hydroxylase 2 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens