[Term]
id: PR:000049527
name: TP53-binding protein 1 phosphorylated 2 (human)
def: "A TP53-binding protein 1 (human) that has been post-translationally modified to include phosphoserine at positions 25 and 1778 of the amino acid sequence represented by UniProtKB:Q12888. UniProtKB:Q12888, Ser-25/Ser-1778, MOD:00046." [PRO:DNx, Reactome:R-HSA-5683418]
comment: Category=organism-modification.
synonym: "hTP53BP1/Phos:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q12888, Ser-25/Ser-1778, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-5683418 "PR:000049527 located_in GO:0005654"
is_a: PR:Q12888 ! TP53-binding protein 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049528
name: TP53-binding protein 1 sumoylated form (human)
def: "A TP53-binding protein 1 (human) that includes at least one sumoylated lysine. UniProtKB:Q12888, MOD:01149." [PRO:DNx, Reactome:R-HSA-2997591]
comment: Category=organism-modification.
synonym: "hTP53BP1/SumoLys+" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q12888, MOD:01149" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-2997591 "PR:000049528 located_in GO:0005654"
intersection_of: has_part MOD:01149 ! sumoylated lysine
intersection_of: PR:Q12888 ! TP53-binding protein 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q12888-1
name: TP53-binding protein 1 isoform h1 (human)
def: "A TP53-binding protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12888-1." [PRO:DNx, UniProtKB:Q12888]
comment: Category=organism-sequence.
synonym: "hTP53BP1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12888-1
is_a: PR:Q12888 ! TP53-binding protein 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q12888-2
name: TP53-binding protein 1 isoform h2 (human)
def: "A TP53-binding protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12888-2." [PRO:DNx, UniProtKB:Q12888]
comment: Category=organism-sequence.
synonym: "hTP53BP1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12888-2
is_a: PR:Q12888 ! TP53-binding protein 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q12888-3
name: TP53-binding protein 1 isoform h3 (human)
def: "A TP53-binding protein 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q12888-3." [PRO:DNx, UniProtKB:Q12888]
comment: Category=organism-sequence.
synonym: "hTP53BP1/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q12888-3
is_a: PR:Q12888 ! TP53-binding protein 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q12888
name: TP53-binding protein 1 (human)
def: "A TP53-binding protein 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q12888]
comment: Category=organism-gene.
synonym: "TP53BP1" RELATED Gene-based [UniProtKB:Q12888]
synonym: "hTP53BP1" EXACT PRO-short-label [PRO:DNx]
synonym: "53BP1 (human)" EXACT [UniProtKB:Q12888]
synonym: "p53BP1 (human)" EXACT [UniProtKB:Q12888]
synonym: "p53-binding protein 1 (human)" EXACT [UniProtKB:Q12888]
xref: UniProtKB:Q12888
xref: Reactome:R-HSA-61175 "PR:Q12888 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016558 ! TP53-binding protein 1
relationship: has_gene_template HGNC:11999 ! TP53BP1 (human)

[Term]
id: PR:000016558
name: TP53-binding protein 1
def: "A protein that is a translation product of the human TP53BP1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "53BP1" EXACT []
synonym: "p53BP1" EXACT []
synonym: "TP53BP1" EXACT PRO-short-label [PRO:DNx]
synonym: "Trp53bp1" RELATED Gene-based []
synonym: "p53-binding protein 1" EXACT []
synonym: "tumor suppressor p53-binding protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000045893
name: TP53-binding protein 1 phosphorylated 1 (human)
def: "A TP53-binding protein 1 (human) that has been phosphorylated at the position equivalent to Ser-1219 of the amino acid sequence represented by UniProtKB:Q12888-1. Example: UniProtKB:Q12888-1, Ser-1219, MOD:00046." [PMID:18996087, iPTMnet:Q12888]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:18996087). Status=unreviewed.
synonym: "hTP53BP1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q12888-1, Ser-1219, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q12888 ! TP53-binding protein 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens