[Term]
id: PR:O43508
name: tumor necrosis factor ligand superfamily member 12 (human)
def: "A tumor necrosis factor ligand superfamily member 12 that is encoded in the genome of human." [PRO:DAN, UniProtKB:O43508]
comment: Category=organism-gene.
synonym: "APO3L" RELATED Gene-based [UniProtKB:O43508]
synonym: "DR3LG" RELATED Gene-based [UniProtKB:O43508]
synonym: "TNFSF12" RELATED Gene-based [UniProtKB:O43508]
synonym: "hTNFSF12" EXACT PRO-short-label [PRO:DNx]
synonym: "TWEAK (human)" EXACT [UniProtKB:O43508]
synonym: "UNQ181/PRO207" RELATED Gene-based [UniProtKB:O43508]
synonym: "APO3 ligand (human)" EXACT [UniProtKB:O43508]
synonym: "TNF-related weak inducer of apoptosis (human)" EXACT [UniProtKB:O43508]
xref: Reactome:R-HSA-5667154 "PR:O43508 located_in GO:0005886"
xref: UniProtKB:O43508
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016487 ! tumor necrosis factor ligand superfamily member 12
relationship: has_gene_template HGNC:11927 ! TNFSF12 (human)

[Term]
id: PR:O43508-1
name: tumor necrosis factor ligand superfamily member 12 isoform 1 (human)
def: "A tumor necrosis factor ligand superfamily member 12 isoform 1 that is encoded in the genome of human." [PRO:DAN]
comment: Category=organism-sequence.
synonym: "hTNFSF12/iso:1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O43508-1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000038144 ! tumor necrosis factor ligand superfamily member 12 isoform 1

[Term]
id: PR:000050752
name: tumor necrosis factor ligand superfamily member 12 O-glycosylated 1 (human)
def: "A tumor necrosis factor ligand superfamily member 12 (human) that has been O-glycosylated at the residue equivalent to Thr-198 of the amino acid sequence represented by UniProtKB:O43508-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:O43508-1, Thr-198, MOD:00005~GNO:G43417UB." [GlyGen:O43508-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTNFSF12/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O43508-1, Thr-198, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:O43508 ! tumor necrosis factor ligand superfamily member 12 (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000016487
name: tumor necrosis factor ligand superfamily member 12
def: "A protein that is a translation product of the human TNFSF12 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "APO3L" RELATED Gene-based []
synonym: "DR3LG" RELATED Gene-based []
synonym: "TWEAK" EXACT []
synonym: "TNFSF12" EXACT PRO-short-label [PRO:DNx]
synonym: "APO3 ligand" EXACT []
synonym: "UNQ181/PRO207" RELATED Gene-based []
synonym: "TNF-related weak inducer of apoptosis" EXACT []
is_a: PR:000000001 ! protein