[Term]
id: PR:F1M391
name: stimulator of interferon genes protein (rat)
def: "A transmembrane protein 173 that is encoded in the genome of rat." [OMA:F1M391, PRO:DNx]
comment: Category=organism-gene.
synonym: "Sting" RELATED Gene-based [UniProtKB:F1M391]
synonym: "Sting1" RELATED Gene-based [UniProtKB:F1M391]
synonym: "rSTING" EXACT [UniProtKB:F1M391]
synonym: "Tmem173" RELATED Gene-based [UniProtKB:F1M391]
synonym: "rSTING1" EXACT PRO-short-label [PRO:DNx]
synonym: "transmembrane protein 173 (rat)" EXACT [UniProtKB:F1M391]
xref: UniProtKB:F1M391
intersection_of: only_in_taxon NCBITaxon:10116 ! Rattus norvegicus
intersection_of: PR:000016417 ! transmembrane protein 173
relationship: has_gene_template RGD:1562552 ! Tmem173 (rat)

[Term]
id: PR:Q86WV6
name: stimulator of interferon genes protein (human)
def: "A transmembrane protein 173 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q86WV6]
comment: Category=organism-gene.
synonym: "ERIS" RELATED Gene-based [UniProtKB:Q86WV6]
synonym: "MITA" RELATED Gene-based [UniProtKB:Q86WV6]
synonym: "STING" RELATED Gene-based [UniProtKB:Q86WV6]
synonym: "hMITA" EXACT [UniProtKB:Q86WV6]
synonym: "STING1" RELATED Gene-based [UniProtKB:Q86WV6]
synonym: "hSTING" EXACT [UniProtKB:Q86WV6]
synonym: "TMEM173" RELATED Gene-based [UniProtKB:Q86WV6]
synonym: "hSTING1" EXACT PRO-short-label [PRO:DNx]
synonym: "transmembrane protein 173 (human)" EXACT [UniProtKB:Q86WV6]
synonym: "mediator of IRF3 activation (human)" EXACT [UniProtKB:Q86WV6]
synonym: "endoplasmic reticulum interferon stimulator (human)" EXACT [UniProtKB:Q86WV6]
xref: UniProtKB:Q86WV6
xref: Reactome:R-HSA-1834940 "PR:Q86WV6 located_in GO:0005789"
xref: Reactome:R-HSA-6804798 "PR:Q86WV6 located_in GO:0030667"
xref: Reactome:R-HSA-6804815 "PR:Q86WV6 located_in GO:0005886"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016417 ! transmembrane protein 173
relationship: has_gene_template HGNC:27962 ! STING1 (human)

[Term]
id: PR:000049479
name: stimulator of interferon genes protein ubiquitinated 1 (human)
def: "A stimulator of interferon genes protein (human) that has been post-translationally modified to include ubiquitinated lysine at position 150 of the amino acid sequence represented by UniProtKB:Q86WV6. UniProtKB:Q86WV6, Lys-150, MOD:01148." [PRO:DNx, Reactome:R-HSA-3134805, Reactome:R-HSA-3248021]
comment: Category=organism-modification.
synonym: "hTMEM173/Ubiq:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q86WV6, Lys-150, MOD:01148" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3134805 "PR:000049479 located_in GO:0005789"
xref: Reactome:R-HSA-3248021 "PR:000049479 located_in GO:0030659"
is_a: PR:Q86WV6 ! stimulator of interferon genes protein (human)
relationship: has_part MOD:01148 ! ubiquitinylated lysine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q3TBT3
name: stimulator of interferon genes protein (mouse)
def: "A transmembrane protein 173 that is encoded in the genome of mouse." [OMA:Q3TBT3, PRO:DNx]
comment: Category=organism-gene.
synonym: "Eris" RELATED Gene-based [UniProtKB:Q3TBT3]
synonym: "Mita" RELATED Gene-based [UniProtKB:Q3TBT3]
synonym: "Mpys" RELATED Gene-based [UniProtKB:Q3TBT3]
synonym: "Sting" RELATED Gene-based [UniProtKB:Q3TBT3]
synonym: "Sting1" RELATED Gene-based [UniProtKB:Q3TBT3]
synonym: "mSTING" EXACT [UniProtKB:Q3TBT3]
synonym: "Tmem173" RELATED Gene-based [UniProtKB:Q3TBT3]
synonym: "mSTING1" EXACT PRO-short-label [PRO:DNx]
synonym: "ERIS (mouse)" EXACT [UniProtKB:Q3TBT3]
synonym: "MMITA (mouse)" EXACT [UniProtKB:Q3TBT3]
synonym: "transmembrane protein 173 (mouse)" EXACT [UniProtKB:Q3TBT3]
synonym: "mediator of IRF3 activation (mouse)" EXACT [UniProtKB:Q3TBT3]
synonym: "endoplasmic reticulum interferon stimulator (mouse)" EXACT [UniProtKB:Q3TBT3]
xref: UniProtKB:Q3TBT3
intersection_of: only_in_taxon NCBITaxon:10090 ! Mus musculus
intersection_of: PR:000016417 ! transmembrane protein 173
relationship: has_gene_template MGI:1919762 ! Sting1 (mouse)

[Term]
id: PR:E1C7U0
name: stimulator of interferon genes protein (chicken)
def: "A transmembrane protein 173 that is encoded in the genome of chicken." [OMA:E1C7U0, PRO:DNx]
comment: Category=organism-gene.
synonym: "STING" RELATED Gene-based [UniProtKB:E1C7U0]
synonym: "STING1" RELATED Gene-based [UniProtKB:E1C7U0]
synonym: "TMEM173" RELATED Gene-based [UniProtKB:E1C7U0]
synonym: "chick-STING1" EXACT PRO-short-label [PRO:DNx]
synonym: "transmembrane protein 173 (chicken)" EXACT [UniProtKB:E1C7U0]
xref: UniProtKB:E1C7U0
intersection_of: only_in_taxon NCBITaxon:9031 ! Gallus gallus
intersection_of: PR:000016417 ! transmembrane protein 173
relationship: has_gene_template NCBIGene:768990 ! STING1 (chicken)

[Term]
id: PR:Q3TBT3-2
name: stimulator of interferon genes protein isoform m2 (mouse)
def: "A stimulator of interferon genes protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3TBT3-2." [PRO:DNx, UniProtKB:Q3TBT3]
comment: Category=organism-sequence.
synonym: "mSTING1/iso:m2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q3TBT3-2
is_a: PR:Q3TBT3 ! stimulator of interferon genes protein (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q3TBT3-1
name: stimulator of interferon genes protein isoform m1 (mouse)
def: "A stimulator of interferon genes protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3TBT3-1." [PRO:DNx, UniProtKB:Q3TBT3]
comment: Category=organism-sequence.
synonym: "mSTING1/iso:m1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q3TBT3-1
is_a: PR:Q3TBT3 ! stimulator of interferon genes protein (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:Q3TBT3-3
name: stimulator of interferon genes protein isoform m3 (mouse)
def: "A stimulator of interferon genes protein (mouse) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q3TBT3-3." [PRO:DNx, UniProtKB:Q3TBT3]
comment: Category=organism-sequence.
synonym: "mSTING1/iso:m3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q3TBT3-3
is_a: PR:Q3TBT3 ! stimulator of interferon genes protein (mouse)
relationship: only_in_taxon NCBITaxon:10090 ! Mus musculus

[Term]
id: PR:000016417
name: transmembrane protein 173
def: "A protein that is a translation product of the human STING1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ERIS" RELATED Gene-based []
synonym: "MITA" RELATED Gene-based []
synonym: "Mpys" RELATED Gene-based []
synonym: "MMITA" EXACT []
synonym: "STING" RELATED Gene-based []
synonym: "STING1" EXACT PRO-short-label [PRO:DNx]
synonym: "TMEM173" RELATED Gene-based []
synonym: "mediator of IRF3 activation" EXACT []
synonym: "stimulator of interferon genes protein" EXACT []
synonym: "endoplasmic reticulum interferon stimulator" EXACT []
xref: IUPHARobj:2902
is_a: PR:000000001 ! protein