[Term]
id: PR:000016368
name: thymidine kinase 2, mitochondrial
def: "A protein that is a translation product of the human TK2 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TK2" EXACT PRO-short-label [PRO:DNx]
synonym: "mt-TK" EXACT []
synonym: "deoxycytidine kinase TK2" EXACT []
synonym: "2'-deoxyuridine kinase TK2" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:O00142-6
name: thymidine kinase 2, mitochondrial isoform h6 (human)
def: "A thymidine kinase 2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00142-6." [PRO:DNx, UniProtKB:O00142]
comment: Category=organism-sequence.
synonym: "hTK2/iso:h6" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00142-6
is_a: PR:O00142 ! thymidine kinase 2, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00142-4
name: thymidine kinase 2, mitochondrial isoform h4 (human)
def: "A thymidine kinase 2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00142-4." [PRO:DNx, UniProtKB:O00142]
comment: Category=organism-sequence.
synonym: "hTK2/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00142-4
is_a: PR:O00142 ! thymidine kinase 2, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00142-5
name: thymidine kinase 2, mitochondrial isoform h5 (human)
def: "A thymidine kinase 2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00142-5." [PRO:DNx, UniProtKB:O00142]
comment: Category=organism-sequence.
synonym: "hTK2/iso:h5" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00142-5
is_a: PR:O00142 ! thymidine kinase 2, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00142-2
name: thymidine kinase 2, mitochondrial isoform h2 (human)
def: "A thymidine kinase 2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00142-2." [PRO:DNx, UniProtKB:O00142]
comment: Category=organism-sequence.
synonym: "hTK2/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00142-2
is_a: PR:O00142 ! thymidine kinase 2, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00142-3
name: thymidine kinase 2, mitochondrial isoform h3 (human)
def: "A thymidine kinase 2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00142-3." [PRO:DNx, UniProtKB:O00142]
comment: Category=organism-sequence.
synonym: "hTK2/iso:h3" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00142-3
is_a: PR:O00142 ! thymidine kinase 2, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00142-1
name: thymidine kinase 2, mitochondrial isoform h1 (human)
def: "A thymidine kinase 2, mitochondrial (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O00142-1." [PRO:DNx, UniProtKB:O00142]
comment: Category=organism-sequence.
synonym: "hTK2/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:O00142-1
is_a: PR:O00142 ! thymidine kinase 2, mitochondrial (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049462
name: thymidine kinase 2, mitochondrial, transit peptide removed form (human)
def: "A thymidine kinase 2, mitochondrial (human) that has had the transit peptide removed. UniProtKB:O00142, 34-265." [PRO:DNx, Reactome:R-HSA-113668, Reactome:R-HSA-58100]
comment: Category=organism-modification.
synonym: "PRO_0000016842" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hTK2/TransPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:O00142, 34-265" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-58100 "PR:000049462 located_in GO:0005759"
xref: Reactome:R-HSA-113668 "PR:000049462 located_in GO:0005654"
intersection_of: PR:O00142 ! thymidine kinase 2, mitochondrial (human)
intersection_of: lacks_part SO:0000725 ! transit_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:O00142
name: thymidine kinase 2, mitochondrial (human)
def: "A thymidine kinase 2, mitochondrial that is encoded in the genome of human." [PRO:DNx, UniProtKB:O00142]
comment: Category=organism-gene.
synonym: "TK2" RELATED Gene-based [UniProtKB:O00142]
synonym: "hTK2" EXACT PRO-short-label [PRO:DNx]
synonym: "mt-TK (human)" EXACT [UniProtKB:O00142]
synonym: "deoxycytidine kinase TK2 (human)" EXACT [UniProtKB:O00142]
synonym: "2'-deoxyuridine kinase TK2 (human)" EXACT [UniProtKB:O00142]
xref: DTO:03100230
xref: UniProtKB:O00142
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016368 ! thymidine kinase 2, mitochondrial
relationship: has_gene_template HGNC:11831 ! TK2 (human)