[Term]
id: PR:000016367
name: thymidine kinase, cytosolic
def: "A protein that is a translation product of the human TK1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TK1" EXACT PRO-short-label [PRO:DNx]
synonym: "Tk-1" RELATED []
is_a: PR:000000001 ! protein

[Term]
id: PR:P04183
name: thymidine kinase, cytosolic (human)
def: "A thymidine kinase, cytosolic that is encoded in the genome of human." [PRO:DNx, UniProtKB:P04183]
comment: Category=organism-gene.
synonym: "TK1" RELATED Gene-based [UniProtKB:P04183]
synonym: "hTK1" EXACT PRO-short-label [PRO:DNx]
xref: DTO:03100229
xref: UniProtKB:P04183
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016367 ! thymidine kinase, cytosolic
relationship: has_gene_template HGNC:11830 ! TK1 (human)

[Term]
id: PR:000049461
name: thymidine kinase, cytosolic, initiator methionine removed form (human)
def: "A thymidine kinase, cytosolic (human) that has had the initiator methionine removed. UniProtKB:P04183, 2-234." [PRO:DNx, Reactome:R-HSA-73500]
comment: Category=organism-modification.
synonym: "hTK1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000174948" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P04183, 2-234" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-73500 "PR:000049461 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:P04183 ! thymidine kinase, cytosolic (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000045635
name: thymidine kinase, cytosolic phosphorylated 1 (human)
def: "A thymidine kinase, cytosolic (human) that has been phosphorylated at Ser-13. UniProtKB:P04183, Ser-13, MOD:00046." [PMID:14697231, PMID:9575153, iPTMnet:P04183]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:14697231, PMID:9575153). Status=unreviewed.
synonym: "hTK1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P04183, Ser-13, MOD:00046" EXACT PRO-proteoform-std [PRO:DNx]
is_a: PR:P04183 ! thymidine kinase, cytosolic (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens