[Term]
id: PR:Q495A1
name: T-cell immunoreceptor with Ig and ITIM domains (human)
def: "A T cell immunoreceptor with Ig and ITIM domains that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q495A1]
comment: Category=organism-gene.
synonym: "TIGIT" RELATED Gene-based [UniProtKB:Q495A1]
synonym: "VSIG9" RELATED Gene-based [UniProtKB:Q495A1]
synonym: "VSTM3" RELATED Gene-based [UniProtKB:Q495A1]
synonym: "hTIGIT" EXACT PRO-short-label [PRO:DNx]
synonym: "V-set and transmembrane domain-containing protein 3 (human)" EXACT [UniProtKB:Q495A1]
synonym: "V-set and immunoglobulin domain-containing protein 9 (human)" EXACT [UniProtKB:Q495A1]
xref: UniProtKB:Q495A1
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016338 ! T cell immunoreceptor with Ig and ITIM domains
relationship: has_gene_template HGNC:26838 ! TIGIT (human)

[Term]
id: PR:000016338
name: T cell immunoreceptor with Ig and ITIM domains
def: "A protein that is a translation product of the human TIGIT gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TIGIT" EXACT PRO-short-label [PRO:DNx]
synonym: "VSIG9" RELATED Gene-based []
synonym: "VSTM3" RELATED Gene-based []
synonym: "V-set and transmembrane domain-containing protein 3" BROAD [PRO:DNx]
synonym: "V-set and immunoglobulin domain-containing protein 9" EXACT []
xref: IUPHARobj:2941
is_a: PR:000000001 ! protein

[Term]
id: PR:Q495A1-1
name: T-cell immunoreceptor with Ig and ITIM domains isoform h1 (human)
def: "A T-cell immunoreceptor with Ig and ITIM domains (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q495A1-1." [PRO:DNx, UniProtKB:Q495A1]
comment: Category=organism-sequence.
synonym: "hTIGIT/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q495A1-1
is_a: PR:Q495A1 ! T-cell immunoreceptor with Ig and ITIM domains (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q495A1-2
name: T-cell immunoreceptor with Ig and ITIM domains isoform h2 (human)
def: "A T-cell immunoreceptor with Ig and ITIM domains (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q495A1-2." [PRO:DNx, UniProtKB:Q495A1]
comment: Category=organism-sequence.
synonym: "hTIGIT/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q495A1-2
is_a: PR:Q495A1 ! T-cell immunoreceptor with Ig and ITIM domains (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens