[Term]
id: PR:Q13009-2
name: Rho guanine nucleotide exchange factor TIAM1 isoform h2 (human)
def: "A Rho guanine nucleotide exchange factor TIAM1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13009-2." [PRO:DNx, UniProtKB:Q13009]
comment: Category=organism-sequence.
synonym: "hTIAM1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13009-2
is_a: PR:Q13009 ! Rho guanine nucleotide exchange factor TIAM1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q13009
name: Rho guanine nucleotide exchange factor TIAM1 (human)
def: "A Rho guanine nucleotide exchange factor TIAM1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q13009]
comment: Category=organism-gene.
synonym: "TIAM1" RELATED Gene-based [UniProtKB:Q13009]
synonym: "hTIAM1" EXACT PRO-short-label [PRO:DNx]
synonym: "TIAM-1 (human)" EXACT [UniProtKB:Q13009]
synonym: "T-lymphoma invasion and metastasis-inducing protein 1 (human)" EXACT [UniProtKB:Q13009]
xref: UniProtKB:Q13009
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016328 ! Rho guanine nucleotide exchange factor TIAM1
relationship: has_gene_template HGNC:11805 ! TIAM1 (human)

[Term]
id: PR:000049450
name: Rho guanine nucleotide exchange factor TIAM1, initiator methionine removed form (human)
def: "A Rho guanine nucleotide exchange factor TIAM1 (human) that has had the initiator methionine removed. UniProtKB:Q13009, 2-1591." [PRO:DNx, Reactome:R-HSA-195013]
comment: Category=organism-modification.
synonym: "PRO_0000080976" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hTIAM1/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q13009, 2-1591" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-195013 "PR:000049450 located_in GO:0005829"
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q13009 ! Rho guanine nucleotide exchange factor TIAM1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049451
name: Rho guanine nucleotide exchange factor TIAM1, initiator methionine removed phosphorylated 1 (human)
def: "A Rho guanine nucleotide exchange factor TIAM1 (human) that has had the initiator methionine removed and has been post-translationally modified to include phosphotyrosine at position 829 of the amino acid sequence represented by UniProtKB:Q13009. UniProtKB:Q13009, 2-1591, Tyr-829, MOD:00048." [PRO:DNx, Reactome:R-HSA-3928461]
comment: Category=organism-modification.
synonym: "hTIAM1/InitMet-/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000080976, Tyr-829, MOD:00048" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:Q13009, 2-1591, Tyr-829, MOD:00048" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-3928461 "PR:000049451 located_in GO:0005829"
is_a: PR:Q13009 ! Rho guanine nucleotide exchange factor TIAM1 (human)
relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens
relationship: lacks_part PR:000021937 ! initiator methionine

[Term]
id: PR:Q13009-1
name: Rho guanine nucleotide exchange factor TIAM1 isoform h1 (human)
def: "A Rho guanine nucleotide exchange factor TIAM1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q13009-1." [PRO:DNx, UniProtKB:Q13009]
comment: Category=organism-sequence.
synonym: "hTIAM1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q13009-1
is_a: PR:Q13009 ! Rho guanine nucleotide exchange factor TIAM1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000016328
name: Rho guanine nucleotide exchange factor TIAM1
def: "A protein that is a translation product of the human TIAM1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TIAM1" EXACT PRO-short-label [PRO:DNx]
synonym: "TIAM-1" EXACT []
synonym: "T-lymphoma invasion and metastasis-inducing protein 1" EXACT []
is_a: PR:000000001 ! protein