[Term] id: PR:000049445 name: thrombospondin type-1 domain-containing protein 4, signal peptide removed form (human) def: "A thrombospondin type-1 domain-containing protein 4 (human) that has had the signal peptide removed. UniProtKB:Q6ZMP0, 26-1018." [PRO:DNx, Reactome:R-HSA-5173065] comment: Category=organism-modification. synonym: "PRO_0000313583" EXACT PRO-proteoform-ftid [PRO:DNx] synonym: "hTHSD4/SigPep-" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q6ZMP0, 26-1018" EXACT PRO-proteoform-std [PRO:DNx] xref: Reactome:R-HSA-5173065 "PR:000049445 located_in GO:0005788" intersection_of: PR:Q6ZMP0 ! thrombospondin type-1 domain-containing protein 4 (human) intersection_of: lacks_part SO:0000418 ! signal_peptide relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q6ZMP0 name: thrombospondin type-1 domain-containing protein 4 (human) def: "A thrombospondin type-1 domain-containing protein 4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q6ZMP0] comment: Category=organism-gene. synonym: "THSD4" RELATED Gene-based [UniProtKB:Q6ZMP0] synonym: "hTHSD4" EXACT PRO-short-label [PRO:DNx] synonym: "UNQ9334/PRO34005" RELATED Gene-based [UniProtKB:Q6ZMP0] synonym: "ADAMTSL-6 (human)" EXACT [UniProtKB:Q6ZMP0] synonym: "ADAMTS-like protein 6 (human)" EXACT [UniProtKB:Q6ZMP0] synonym: "a disintegrin and metalloproteinase with thrombospondin motifs-like protein 6 (human)" EXACT [UniProtKB:Q6ZMP0] xref: UniProtKB:Q6ZMP0 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000016323 ! thrombospondin type-1 domain-containing protein 4 relationship: has_gene_template HGNC:25835 ! THSD4 (human) [Term] id: PR:Q6ZMP0-4 name: thrombospondin type-1 domain-containing protein 4 isoform h4 (human) def: "A thrombospondin type-1 domain-containing protein 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZMP0-4." [PRO:DNx, UniProtKB:Q6ZMP0] comment: Category=organism-sequence. synonym: "hTHSD4/iso:h4" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6ZMP0-4 is_a: PR:Q6ZMP0 ! thrombospondin type-1 domain-containing protein 4 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q6ZMP0-2 name: thrombospondin type-1 domain-containing protein 4 isoform h2 (human) def: "A thrombospondin type-1 domain-containing protein 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZMP0-2." [PRO:DNx, UniProtKB:Q6ZMP0] comment: Category=organism-sequence. synonym: "hTHSD4/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6ZMP0-2 is_a: PR:Q6ZMP0 ! thrombospondin type-1 domain-containing protein 4 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q6ZMP0-3 name: thrombospondin type-1 domain-containing protein 4 isoform h3 (human) def: "A thrombospondin type-1 domain-containing protein 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZMP0-3." [PRO:DNx, UniProtKB:Q6ZMP0] comment: Category=organism-sequence. synonym: "hTHSD4/iso:h3" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6ZMP0-3 is_a: PR:Q6ZMP0 ! thrombospondin type-1 domain-containing protein 4 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:Q6ZMP0-1 name: thrombospondin type-1 domain-containing protein 4 isoform h1 (human) def: "A thrombospondin type-1 domain-containing protein 4 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q6ZMP0-1." [PRO:DNx, UniProtKB:Q6ZMP0] comment: Category=organism-sequence. synonym: "hTHSD4/iso:h1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:Q6ZMP0-1 is_a: PR:Q6ZMP0 ! thrombospondin type-1 domain-containing protein 4 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000016323 name: thrombospondin type-1 domain-containing protein 4 def: "A protein that is a translation product of the human THSD4 gene or a 1:1 ortholog thereof." [PRO:DNx] comment: Category=gene. synonym: "THSD4" EXACT PRO-short-label [PRO:DNx] synonym: "ADAMTSL-4" RELATED [] synonym: "ADAMTSL-6" EXACT [] synonym: "UNQ9334/PRO34005" RELATED Gene-based [] synonym: "ADAMTS-like protein 6" EXACT [] synonym: "a disintegrin and metalloproteinase with thrombospondin motifs-like protein 6" EXACT [] is_a: PR:000000001 ! protein [Term] id: PR:000057501 name: thrombospondin type-1 domain-containing protein 4 O-glycosylated 1 (human) def: "A thrombospondin type-1 domain-containing protein 4 (human) that has been O-glycosylated at the residue equivalent to Ser-583 of the amino acid sequence represented by UniProtKB:Q6ZMP0-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q6ZMP0-1, Ser-583, MOD:00002~GNO:G43417UB." [GlyGen:Q6ZMP0-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hTHSD4/OGlyco:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q6ZMP0-1, Ser-583, MOD:00002~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q6ZMP0 ! thrombospondin type-1 domain-containing protein 4 (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00002 ! O-glycosyl-L-serine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000057503 name: thrombospondin type-1 domain-containing protein 4 O-glycosylated 3 (human) def: "A thrombospondin type-1 domain-containing protein 4 (human) that has been O-glycosylated at the residue equivalent to Thr-582 of the amino acid sequence represented by UniProtKB:Q6ZMP0-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q6ZMP0-1, Thr-582, MOD:00005~GNO:G43417UB." [GlyGen:Q6ZMP0-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hTHSD4/OGlyco:3" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q6ZMP0-1, Thr-582, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q6ZMP0 ! thrombospondin type-1 domain-containing protein 4 (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000057502 name: thrombospondin type-1 domain-containing protein 4 O-glycosylated 2 (human) def: "A thrombospondin type-1 domain-containing protein 4 (human) that has been O-glycosylated at the residue equivalent to Thr-277 of the amino acid sequence represented by UniProtKB:Q6ZMP0-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:Q6ZMP0-1, Thr-277, MOD:00005~GNO:G43417UB." [GlyGen:Q6ZMP0-1, PMID:30459171, PRO:DNx] comment: Category=organism-modification. Requested by=GlyGen. synonym: "hTHSD4/OGlyco:2" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:Q6ZMP0-1, Thr-277, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:Q6ZMP0 ! thrombospondin type-1 domain-containing protein 4 (human) relationship: has_part GNO:G43417UB ! G43417UB relationship: has_part MOD:00005 ! O-glycosyl-L-threonine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens