[Term]
id: PR:000056511
name: thrombopoietin N-glycosylated 12 (human)
def: "A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G94531EZ. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G94531EZ." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTHPO/NGlyco:12" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G94531EZ" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~UniCarbKB:1199" NARROW [PRO:DNx]
is_a: PR:P40225 ! thrombopoietin (human)
relationship: has_part GNO:G94531EZ ! G94531EZ
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049443
name: thrombopoietin, signal peptide removed form (human)
def: "A thrombopoietin (human) that has had the signal peptide removed. UniProtKB:P40225, 22-353." [PRO:DNx, Reactome:R-HSA-443917]
comment: Category=organism-modification.
synonym: "hTHPO/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000008411" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P40225, 22-353" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-443917 "PR:000049443 located_in GO:0005576"
intersection_of: PR:P40225 ! thrombopoietin (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P40225-2
name: thrombopoietin isoform h2 (human)
def: "A thrombopoietin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40225-2." [PRO:DNx, UniProtKB:P40225]
comment: Category=organism-sequence.
synonym: "hTHPO/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "thrombopoietin isoform TPO-2 (human)" EXACT [UniProtKB:P40225]
xref: UniProtKB:P40225-2
is_a: PR:P40225 ! thrombopoietin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056510
name: thrombopoietin N-glycosylated 11 (human)
def: "A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G90352XZ. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G90352XZ." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTHPO/NGlyco:11" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G90352XZ" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~UniCarbKB:7150" NARROW [PRO:DNx]
is_a: PR:P40225 ! thrombopoietin (human)
relationship: has_part GNO:G90352XZ ! G90352XZ
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P40225
name: thrombopoietin (human)
def: "A thrombopoietin that is encoded in the genome of human." [PRO:DNx, UniProtKB:P40225]
comment: Category=organism-gene.
synonym: "MGDF" RELATED Gene-based [UniProtKB:P40225]
synonym: "THPO" RELATED Gene-based [UniProtKB:P40225]
synonym: "hTHPO" EXACT PRO-short-label [PRO:DNx]
synonym: "ML (human)" EXACT [UniProtKB:P40225]
synonym: "C-mpl ligand (human)" EXACT [UniProtKB:P40225]
synonym: "megakaryocyte colony-stimulating factor (human)" EXACT [UniProtKB:P40225]
synonym: "megakaryocyte growth and development factor (human)" EXACT [UniProtKB:P40225]
synonym: "myeloproliferative leukemia virus oncogene ligand (human)" EXACT [UniProtKB:P40225]
xref: UniProtKB:P40225
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016318 ! thrombopoietin
relationship: has_gene_template HGNC:11795 ! THPO (human)

[Term]
id: PR:P40225-1
name: thrombopoietin isoform h1 (human)
def: "A thrombopoietin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40225-1." [PRO:DNx, UniProtKB:P40225]
comment: Category=organism-sequence.
synonym: "hTHPO/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P40225-1
is_a: PR:P40225 ! thrombopoietin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P40225-3
name: thrombopoietin isoform h3 (human)
def: "A thrombopoietin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P40225-3." [PRO:DNx, UniProtKB:P40225]
comment: Category=organism-sequence.
synonym: "hTHPO/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "thrombopoietin isoform Truncated (human)" EXACT [UniProtKB:P40225]
xref: UniProtKB:P40225-3
is_a: PR:P40225 ! thrombopoietin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056506
name: thrombopoietin N-glycosylated 7 (human)
def: "A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G44444MB. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G44444MB." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTHPO/NGlyco:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G44444MB" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~UniCarbKB:3055" NARROW [PRO:DNx]
is_a: PR:P40225 ! thrombopoietin (human)
relationship: has_part GNO:G44444MB ! G44444MB
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056507
name: thrombopoietin N-glycosylated 8 (human)
def: "A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G47058MH. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G47058MH." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTHPO/NGlyco:8" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G47058MH" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~UniCarbKB:5360" NARROW [PRO:DNx]
is_a: PR:P40225 ! thrombopoietin (human)
relationship: has_part GNO:G47058MH ! G47058MH
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056504
name: thrombopoietin N-glycosylated 5 (human)
def: "A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G16265MV. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G16265MV." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTHPO/NGlyco:5" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G16265MV" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~UniCarbKB:7148" NARROW [PRO:DNx]
is_a: PR:P40225 ! thrombopoietin (human)
relationship: has_part GNO:G16265MV ! G16265MV
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056505
name: thrombopoietin N-glycosylated 6 (human)
def: "A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G17689DH. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G17689DH." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTHPO/NGlyco:6" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G17689DH" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~UniCarbKB:1189" NARROW [PRO:DNx]
is_a: PR:P40225 ! thrombopoietin (human)
relationship: has_part GNO:G17689DH ! G17689DH
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056502
name: thrombopoietin N-glycosylated 3 (human)
def: "A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G01817YC. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G01817YC." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTHPO/NGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G01817YC" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~UniCarbKB:7152" NARROW [PRO:DNx]
is_a: PR:P40225 ! thrombopoietin (human)
relationship: has_part GNO:G01817YC ! G01817YC
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056503
name: thrombopoietin N-glycosylated 4 (human)
def: "A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G14389GM. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G14389GM." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTHPO/NGlyco:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G14389GM" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~UniCarbKB:3423" NARROW [PRO:DNx]
is_a: PR:P40225 ! thrombopoietin (human)
relationship: has_part GNO:G14389GM ! G14389GM
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056500
name: thrombopoietin N-glycosylated 1 (human)
def: "A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G00227RN. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G00227RN." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTHPO/NGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G00227RN" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~UniCarbKB:7149" NARROW [PRO:DNx]
is_a: PR:P40225 ! thrombopoietin (human)
relationship: has_part GNO:G00227RN ! G00227RN
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056501
name: thrombopoietin N-glycosylated 2 (human)
def: "A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G00800WJ. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G00800WJ." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTHPO/NGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G00800WJ" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~UniCarbKB:7151" NARROW [PRO:DNx]
is_a: PR:P40225 ! thrombopoietin (human)
relationship: has_part GNO:G00800WJ ! G00800WJ
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056509
name: thrombopoietin N-glycosylated 10 (human)
def: "A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G57789QC. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G57789QC." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTHPO/NGlyco:10" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G57789QC" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~UniCarbKB:2149" NARROW [PRO:DNx]
is_a: PR:P40225 ! thrombopoietin (human)
relationship: has_part GNO:G57789QC ! G57789QC
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000056508
name: thrombopoietin N-glycosylated 9 (human)
def: "A thrombopoietin (human) that has been N-glycosylated at the residue equivalent to Asn-197 of the amino acid sequence represented by UniProtKB:P40225-1, in which the glycan structure is represented by GlyTouCan:G56501FP. Example: UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G56501FP." [GlyGen:P40225-1, PMID:8942648, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hTHPO/NGlyco:9" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~GNO:G56501FP" NARROW PRO-proteoform-std [PRO:DNx]
synonym: "UniProtKB:P40225-1, Asn-197, MOD:00160~UniCarbKB:7153" NARROW [PRO:DNx]
is_a: PR:P40225 ! thrombopoietin (human)
relationship: has_part GNO:G56501FP ! G56501FP
relationship: has_part MOD:00160 ! N4-glycosyl-L-asparagine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000016318
name: thrombopoietin
def: "A protein that is a translation product of the human THPO gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ML" EXACT []
synonym: "MGDF" RELATED Gene-based []
synonym: "THPO" EXACT PRO-short-label [PRO:DNx]
synonym: "C-mpl ligand" EXACT []
synonym: "megakaryocyte colony-stimulating factor" EXACT []
synonym: "megakaryocyte growth and development factor" EXACT []
synonym: "myeloproliferative leukemia virus oncogene ligand" EXACT []
is_a: PR:000000001 ! protein