[Term]
id: PR:000046327
name: THO complex subunit 4, initiator methionine removed form (human)
def: "A THO complex subunit 4 (human) that has had the initiator methionine removed. UniProtKB:Q86V81, 2-257." [PRO:DNx, Reactome:R-HSA-156649, Reactome:R-HSA-158482]
comment: Category=organism-modification.
synonym: "PRO_0000081974" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "hALYREF/InitMet-" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q86V81, 2-257" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-156649 "PR:000046327 located_in GO:0005654"
xref: Reactome:R-HSA-158482 "PR:000046327 located_in GO:0005829"
xref: TDR:4300
intersection_of: lacks_part PR:000021937 ! initiator methionine
intersection_of: PR:Q86V81 ! THO complex subunit 4 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000016313
name: THO complex subunit 4
def: "A protein that is a translation product of the human ALYREF gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "ALY" RELATED Gene-based []
synonym: "BEF" RELATED Gene-based []
synonym: "Ref1" RELATED Gene-based []
synonym: "tho4" EXACT []
synonym: "THOC4" RELATED Gene-based []
synonym: "ALYREF" EXACT PRO-short-label [PRO:DNx]
synonym: "REF1-I" EXACT []
synonym: "Refbp1" RELATED Gene-based []
synonym: "Aly/REF export factor" EXACT []
synonym: "Ally of AML-1 and LEF-1" EXACT []
synonym: "bZIP-enhancing factor BEF" EXACT []
synonym: "transcriptional coactivator Aly/REF" EXACT []
synonym: "RNA and export factor-binding protein 1" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:Q86V81
name: THO complex subunit 4 (human)
def: "A THO complex subunit 4 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q86V81]
comment: Category=organism-gene.
synonym: "ALY" RELATED Gene-based [UniProtKB:Q86V81]
synonym: "BEF" RELATED Gene-based [UniProtKB:Q86V81]
synonym: "THOC4" RELATED Gene-based [UniProtKB:Q86V81]
synonym: "ALYREF" RELATED Gene-based [UniProtKB:Q86V81]
synonym: "hALYREF" EXACT PRO-short-label [PRO:DNx]
synonym: "Tho4 (human)" EXACT [UniProtKB:Q86V81]
synonym: "Aly/REF export factor (human)" EXACT [UniProtKB:Q86V81]
synonym: "Ally of AML-1 and LEF-1 (human)" EXACT [UniProtKB:Q86V81]
synonym: "bZIP-enhancing factor BEF (human)" EXACT [UniProtKB:Q86V81]
synonym: "transcriptional coactivator Aly/REF (human)" EXACT [UniProtKB:Q86V81]
xref: UniProtKB:Q86V81
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016313 ! THO complex subunit 4
relationship: has_gene_template HGNC:19071 ! ALYREF (human)