[Term]
id: PR:Q9NUW8-1
name: tyrosyl-DNA phosphodiesterase 1 isoform h1 (human)
def: "A tyrosyl-DNA phosphodiesterase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NUW8-1." [PRO:DNx, UniProtKB:Q9NUW8]
comment: Category=organism-sequence.
synonym: "hTDP1/iso:h1" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NUW8-1
is_a: PR:Q9NUW8 ! tyrosyl-DNA phosphodiesterase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9NUW8-2
name: tyrosyl-DNA phosphodiesterase 1 isoform h2 (human)
def: "A tyrosyl-DNA phosphodiesterase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:Q9NUW8-2." [PRO:DNx, UniProtKB:Q9NUW8]
comment: Category=organism-sequence.
synonym: "hTDP1/iso:h2" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:Q9NUW8-2
is_a: PR:Q9NUW8 ! tyrosyl-DNA phosphodiesterase 1 (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000046073
name: tyrosyl-DNA phosphodiesterase 1 phosphorylated 1 (human)
def: "A tyrosyl-DNA phosphodiesterase 1 (human) that has been phosphorylated at the position equivalent to Ser-81 of the amino acid sequence represented by UniProtKB:Q9NUW8-1. Example: UniProtKB:Q9NUW8-1, Ser-81, MOD:00046." [PMID:19851285, iPTMnet:Q9NUW8]
comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:19851285). Status=unreviewed.
synonym: "hTDP1/Phos:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:Q9NUW8-1, Ser-81, MOD:00046" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:Q9NUW8 ! tyrosyl-DNA phosphodiesterase 1 (human)
relationship: has_part MOD:00046 ! O-phospho-L-serine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:Q9NUW8
name: tyrosyl-DNA phosphodiesterase 1 (human)
def: "A tyrosyl-DNA phosphodiesterase 1 that is encoded in the genome of human." [PRO:DNx, UniProtKB:Q9NUW8]
comment: Category=organism-gene.
synonym: "TDP1" RELATED Gene-based [UniProtKB:Q9NUW8]
synonym: "hTDP1" EXACT PRO-short-label [PRO:DNx]
synonym: "Tyr-DNA phosphodiesterase 1 (human)" EXACT [UniProtKB:Q9NUW8]
xref: UniProtKB:Q9NUW8
xref: Reactome:R-HSA-175593 "PR:Q9NUW8 located_in GO:0005654"
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000016215 ! tyrosyl-DNA phosphodiesterase 1
relationship: has_gene_template HGNC:18884 ! TDP1 (human)

[Term]
id: PR:000016215
name: tyrosyl-DNA phosphodiesterase 1
def: "A protein that is a translation product of the human TDP1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "TDP1" EXACT PRO-short-label [PRO:DNx]
synonym: "Tyr-DNA phosphodiesterase 1" EXACT []
is_a: PR:000000001 ! protein