[Term] id: PR:O15269-2 name: serine palmitoyltransferase 1 isoform h2 (human) def: "A serine palmitoyltransferase 1 (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:O15269-2." [PRO:DNx, UniProtKB:O15269] comment: Category=organism-sequence. synonym: "hSPTLC1/iso:h2" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O15269-2 is_a: PR:O15269 ! serine palmitoyltransferase 1 (human) relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens [Term] id: PR:000015596 name: serine palmitoyltransferase 1 def: "A eukaryotic serine palmitoyltransferase that is a translation product of the human SPTLC1 gene or a 1:1 ortholog thereof." [PRO:CNA] comment: Category=gene. synonym: "LCB1" RELATED Gene-based [] synonym: "SPT1" EXACT [] synonym: "LCB 1" EXACT [] synonym: "SPT 1" EXACT [] synonym: "SPTLC1" EXACT PRO-short-label [PRO:DNx] synonym: "serine-palmitoyl-CoA transferase 1" EXACT [] synonym: "long chain base biosynthesis protein 1" EXACT [] xref: IUPHARobj:2509 is_a: PR:000026126 ! eukaryotic serine palmitoyltransferase [Term] id: PR:O15269 name: serine palmitoyltransferase 1 (human) def: "A serine palmitoyltransferase 1 that is encoded in the genome of human." [PRO:CNA] comment: Category=organism-gene. synonym: "LCB1" RELATED Gene-based [UniProtKB:O15269] synonym: "SPTLC1" RELATED Gene-based [UniProtKB:O15269] synonym: "hSPTLC1" EXACT PRO-short-label [PRO:DNx] synonym: "SPT1 (human)" EXACT [UniProtKB:O15269] synonym: "LCB 1 (human)" EXACT [UniProtKB:O15269] synonym: "SPT 1 (human)" EXACT [UniProtKB:O15269] synonym: "serine-palmitoyl-CoA transferase 1 (human)" EXACT [UniProtKB:O15269] synonym: "long chain base biosynthesis protein 1 (human)" EXACT [UniProtKB:O15269] xref: UniProtKB:O15269 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000015596 ! serine palmitoyltransferase 1 relationship: has_gene_template HGNC:11277 ! SPTLC1 (human) [Term] id: PR:O15269-1 name: serine palmitoyltransferase 1 isoform 1 (human) def: "A serine palmitoyltransferase 1 isoform 1 that is encoded in the genome of human." [PRO:HJD] comment: Category=organism-sequence. synonym: "hSPTLC1/iso:1" EXACT PRO-short-label [PRO:DNx] xref: UniProtKB:O15269-1 intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens intersection_of: PR:000022019 ! serine palmitoyltransferase 1 isoform 1 [Term] id: PR:000045580 name: serine palmitoyltransferase 1 phosphorylated 1 (human) def: "A serine palmitoyltransferase 1 (human) that has been phosphorylated at the position equivalent to Tyr-164 of the amino acid sequence represented by UniProtKB:O15269-1. Example: UniProtKB:O15269-1, Tyr-164, MOD:00048." [PMID:23629659, iPTMnet:O15269] comment: Category=organism-modification. Evidence=(ECO:0000006, based on PMID:23629659). Status=unreviewed. synonym: "hSPTLC1/Phos:1" EXACT PRO-short-label [PRO:DNx] synonym: "UniProtKB:O15269-1, Tyr-164, MOD:00048" NARROW PRO-proteoform-std [PRO:DNx] is_a: PR:O15269 ! serine palmitoyltransferase 1 (human) relationship: has_part MOD:00048 ! O4'-phospho-L-tyrosine relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens