[Term]
id: PR:P10451-5
name: osteopontin isoform h2 (human)
def: "An osteopontin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10451-5." [PRO:DNx, UniProtKB:P10451]
comment: Category=organism-sequence.
synonym: "hSPP1/iso:h2" EXACT PRO-short-label [PRO:DNx]
synonym: "osteopontin isoform OP1A (human)" EXACT [UniProtKB:P10451]
synonym: "osteopontin isoform OPN-b (human)" EXACT [UniProtKB:P10451]
xref: UniProtKB:P10451-5
is_a: PR:P10451 ! osteopontin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P10451-4
name: osteopontin isoform h4 (human)
def: "An osteopontin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10451-4." [PRO:DNx, UniProtKB:P10451]
comment: Category=organism-sequence.
synonym: "hSPP1/iso:h4" EXACT PRO-short-label [PRO:DNx]
xref: UniProtKB:P10451-4
is_a: PR:P10451 ! osteopontin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P10451-3
name: osteopontin isoform h3 (human)
def: "An osteopontin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10451-3." [PRO:DNx, UniProtKB:P10451]
comment: Category=organism-sequence.
synonym: "hSPP1/iso:h3" EXACT PRO-short-label [PRO:DNx]
synonym: "osteopontin isoform OPN-c (human)" EXACT [UniProtKB:P10451]
xref: UniProtKB:P10451-3
is_a: PR:P10451 ! osteopontin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P10451-1
name: osteopontin isoform h1 (human)
def: "An osteopontin (human) that is a translation product of some mRNA whose exon structure and start site selection renders it capable of giving rise to a protein with the amino acid sequence represented by UniProtKB:P10451-1." [PRO:DNx, UniProtKB:P10451]
comment: Category=organism-sequence.
synonym: "hSPP1/iso:h1" EXACT PRO-short-label [PRO:DNx]
synonym: "osteopontin isoform OP1B (human)" EXACT [UniProtKB:P10451]
synonym: "osteopontin isoform OPN-a (human)" EXACT [UniProtKB:P10451]
xref: UniProtKB:P10451-1
is_a: PR:P10451 ! osteopontin (human)
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000015561
name: osteopontin
def: "A protein that is a translation product of the human SPP1 gene or a 1:1 ortholog thereof." [PRO:DNx]
comment: Category=gene.
synonym: "Op" RELATED Gene-based []
synonym: "2AR" EXACT []
synonym: "OPN" RELATED Gene-based []
synonym: "BNSP" RELATED Gene-based []
synonym: "SPP1" EXACT PRO-short-label [PRO:DNx]
synonym: "Eta-1" RELATED Gene-based []
synonym: "SPP-1" EXACT []
synonym: "PSEC0156" RELATED Gene-based []
synonym: "uropontin" EXACT []
synonym: "minopontin" EXACT []
synonym: "nephropontin" EXACT []
synonym: "bone sialoprotein 1" EXACT []
synonym: "urinary stone protein" EXACT []
synonym: "secreted phosphoprotein 1" EXACT []
synonym: "early T-lymphocyte activation 1 protein" EXACT []
synonym: "calcium oxalate crystal growth inhibitor protein" EXACT []
is_a: PR:000000001 ! protein

[Term]
id: PR:000054756
name: osteopontin O-glycosylated 8 (human)
def: "An osteopontin (human) that has been O-glycosylated at the residue equivalent to Thr-152 of the amino acid sequence represented by UniProtKB:P10451-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P10451-1, Thr-152, MOD:00005~GNO:G43417UB." [GlyGen:P10451-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hSPP1/OGlyco:8" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10451-1, Thr-152, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P10451 ! osteopontin (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000049332
name: osteopontin, signal peptide removed form (human)
def: "An osteopontin (human) that has had the signal peptide removed. UniProtKB:P10451, 17-314." [PRO:DNx, Reactome:R-HSA-215967]
comment: Category=organism-modification.
synonym: "hSPP1/SigPep-" EXACT PRO-short-label [PRO:DNx]
synonym: "PRO_0000020321" EXACT PRO-proteoform-ftid [PRO:DNx]
synonym: "UniProtKB:P10451, 17-314" EXACT PRO-proteoform-std [PRO:DNx]
xref: Reactome:R-HSA-215967 "PR:000049332 located_in GO:0005576"
xref: Reactome:R-HSA-8956713 "PR:000049332 located_in GO:0005788"
intersection_of: PR:P10451 ! osteopontin (human)
intersection_of: lacks_part SO:0000418 ! signal_peptide
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054755
name: osteopontin O-glycosylated 7 (human)
def: "An osteopontin (human) that has been O-glycosylated at the residue equivalent to Thr-147 of the amino acid sequence represented by UniProtKB:P10451-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P10451-1, Thr-147, MOD:00005~GNO:G58001LT." [GlyGen:P10451-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hSPP1/OGlyco:7" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10451-1, Thr-147, MOD:00005~GNO:G58001LT" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P10451 ! osteopontin (human)
relationship: has_part GNO:G58001LT ! G58001LT
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054754
name: osteopontin O-glycosylated 6 (human)
def: "An osteopontin (human) that has been O-glycosylated at the residue equivalent to Thr-147 of the amino acid sequence represented by UniProtKB:P10451-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P10451-1, Thr-147, MOD:00005~GNO:G43417UB." [GlyGen:P10451-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hSPP1/OGlyco:6" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10451-1, Thr-147, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P10451 ! osteopontin (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054757
name: osteopontin O-glycosylated 9 (human)
def: "An osteopontin (human) that has been O-glycosylated at the residue equivalent to Thr-42 of the amino acid sequence represented by UniProtKB:P10451-1, in which the glycan composition is represented by GlyTouCan:G43417UB. Example: UniProtKB:P10451-1, Thr-42, MOD:00005~GNO:G43417UB." [GlyGen:P10451-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hSPP1/OGlyco:9" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10451-1, Thr-42, MOD:00005~GNO:G43417UB" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P10451 ! osteopontin (human)
relationship: has_part GNO:G43417UB ! G43417UB
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054749
name: osteopontin O-glycosylated 1 (human)
def: "An osteopontin (human) that has been O-glycosylated at the residue equivalent to Thr-143 of the amino acid sequence represented by UniProtKB:P10451-1, in which the glycan composition is represented by GlyTouCan:G40740AD. Example: UniProtKB:P10451-1, Thr-143, MOD:00005~GNO:G40740AD." [GlyGen:P10451-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hSPP1/OGlyco:1" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10451-1, Thr-143, MOD:00005~GNO:G40740AD" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P10451 ! osteopontin (human)
relationship: has_part GNO:G40740AD ! G40740AD
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054751
name: osteopontin O-glycosylated 3 (human)
def: "An osteopontin (human) that has been O-glycosylated at the residue equivalent to Thr-143 of the amino acid sequence represented by UniProtKB:P10451-1, in which the glycan composition is represented by GlyTouCan:G88713AC. Example: UniProtKB:P10451-1, Thr-143, MOD:00005~GNO:G88713AC." [GlyGen:P10451-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hSPP1/OGlyco:3" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10451-1, Thr-143, MOD:00005~GNO:G88713AC" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P10451 ! osteopontin (human)
relationship: has_part GNO:G88713AC ! G88713AC
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054750
name: osteopontin O-glycosylated 2 (human)
def: "An osteopontin (human) that has been O-glycosylated at the residue equivalent to Thr-143 of the amino acid sequence represented by UniProtKB:P10451-1, in which the glycan composition is represented by GlyTouCan:G58001LT. Example: UniProtKB:P10451-1, Thr-143, MOD:00005~GNO:G58001LT." [GlyGen:P10451-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hSPP1/OGlyco:2" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10451-1, Thr-143, MOD:00005~GNO:G58001LT" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P10451 ! osteopontin (human)
relationship: has_part GNO:G58001LT ! G58001LT
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054753
name: osteopontin O-glycosylated 5 (human)
def: "An osteopontin (human) that has been O-glycosylated at the residue equivalent to Thr-147 of the amino acid sequence represented by UniProtKB:P10451-1, in which the glycan composition is represented by GlyTouCan:G29068FM. Example: UniProtKB:P10451-1, Thr-147, MOD:00005~GNO:G29068FM." [GlyGen:P10451-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hSPP1/OGlyco:5" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10451-1, Thr-147, MOD:00005~GNO:G29068FM" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P10451 ! osteopontin (human)
relationship: has_part GNO:G29068FM ! G29068FM
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:000054752
name: osteopontin O-glycosylated 4 (human)
def: "An osteopontin (human) that has been O-glycosylated at the residue equivalent to Thr-147 of the amino acid sequence represented by UniProtKB:P10451-1, in which the glycan composition is represented by GlyTouCan:G27391WQ. Example: UniProtKB:P10451-1, Thr-147, MOD:00005~GNO:G27391WQ." [GlyGen:P10451-1, PMID:30459171, PRO:DNx]
comment: Category=organism-modification. Requested by=GlyGen.
synonym: "hSPP1/OGlyco:4" EXACT PRO-short-label [PRO:DNx]
synonym: "UniProtKB:P10451-1, Thr-147, MOD:00005~GNO:G27391WQ" NARROW PRO-proteoform-std [PRO:DNx]
is_a: PR:P10451 ! osteopontin (human)
relationship: has_part GNO:G27391WQ ! G27391WQ
relationship: has_part MOD:00005 ! O-glycosyl-L-threonine
relationship: only_in_taxon NCBITaxon:9606 ! Homo sapiens

[Term]
id: PR:P10451
name: osteopontin (human)
def: "An osteopontin that is encoded in the genome of human." [PRO:DNx, UniProtKB:P10451]
comment: Category=organism-gene.
synonym: "OPN" RELATED Gene-based [UniProtKB:P10451]
synonym: "BNSP" RELATED Gene-based [UniProtKB:P10451]
synonym: "SPP1" RELATED Gene-based [UniProtKB:P10451]
synonym: "hSPP1" EXACT PRO-short-label [PRO:DNx]
synonym: "PSEC0156" RELATED Gene-based [UniProtKB:P10451]
synonym: "SPP-1 (human)" BROAD [UniProtKB:P10451]
synonym: "uropontin (human)" EXACT [UniProtKB:P10451]
synonym: "nephropontin (human)" EXACT [UniProtKB:P10451]
synonym: "bone sialoprotein 1 (human)" EXACT [UniProtKB:P10451]
synonym: "urinary stone protein (human)" EXACT [UniProtKB:P10451]
synonym: "secreted phosphoprotein 1 (human)" EXACT [UniProtKB:P10451]
xref: Reactome:R-HSA-4093349 "PR:P10451 located_in GO:0005576"
xref: UniProtKB:P10451
intersection_of: only_in_taxon NCBITaxon:9606 ! Homo sapiens
intersection_of: PR:000015561 ! osteopontin
relationship: has_gene_template HGNC:11255 ! SPP1 (human)